Ligand Pharmaceuticals (LGND) Operating Margin (2010 - 2026)

Ligand Pharmaceuticals' (LGND) quarterly Operating Margin came in at 33.58% in Q1 2026, up 11347.0% year-on-year from N/an in Q1 2025, and up 44.73% quarter-over-quarter from 23.2% in Q4 2025.

Ligand Pharmaceuticals (LGND) Operating Margin (2010 - 2026) Analysis & Trends

Ligand Pharmaceuticals has disclosed Operating Margin across 17 years of filings, most recently posting 33.58% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 33.58%, up 11347.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 34.46% (up 6852.0% YoY), and the FY2025 annual result was 15.29%, up 2882.0% from the prior year.
  • Operating Margin came in at 33.58% for Q1 2026 at Ligand Pharmaceuticals, up from 23.2% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 47.58% in Q3 2025 to a low of 79.89% in Q1 2025.
  • The 5-year median for Operating Margin is 9.36% (2023), against an average of 0.92%.
  • Across the five-year window, Operating Margin tumbled 10671 bps in 2022 and soared 11347 bps in 2026, its largest moves.
  • Ligand Pharmaceuticals' Operating Margin stood at 39.89% in 2022, then jumped by 70 bps to 11.95% in 2023, then plunged by 88 bps to 22.51% in 2024, then soared by 203 bps to 23.2% in 2025, then jumped by 45 bps to 33.58% in 2026.
  • The last three Operating Margin figures came in at 33.58% (Q1 2026), 23.2% (Q4 2025), and 47.58% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Ligand Pharmaceuticals 5.47 Bn 4.69 Bn 48.45 Mn 33.58%

Historic Data

Download Data
DateValue
Mar 31, 2026 33.58%
Dec 31, 2025 23.20%
Sep 30, 2025 47.58%
Jun 30, 2025 17.73%
Mar 31, 2025 -79.89%
Dec 31, 2024 -22.51%
Sep 30, 2024 6.07%
Jun 30, 2024 -45.99%
Mar 31, 2024 9.65%
Dec 31, 2023 -11.95%
Sep 30, 2023 9.36%
Jun 30, 2023 -7.52%
Mar 31, 2023 32.30%
Dec 31, 2022 -39.89%
Sep 30, 2022 20.84%
Jun 30, 2022 17.28%
Mar 31, 2022 5.84%
Dec 31, 2021 66.82%
Sep 30, 2021 26.31%
Jun 30, 2021 58.00%