Korro Bio (KRRO) Operating Margin (2019 - 2025)
Korro Bio's Operating Margin came in at -3900.62% for Q4 2025, down 2886.09 percentage points from -1014.53% a year earlier and down 2135.76 percentage points from the prior quarter.
Powered by 
Analysis
Korro Bio (KRRO) Operating Margin (2019 - 2025) Analysis & Trends
For FY2025, Korro Bio's Operating Margin was -1906.37%, up 2140.75 percentage points from FY2024.
- Operating Margin carries a five-year change of -1831.88 percentage points (FY2020 to FY2025).
- Going back by year, Operating Margin was -4047.12% in FY2024 and -597.32% in FY2021 (-522.83 pp).
- The Q4 2025 figure represents the lowest quarterly Operating Margin in data going back to Q3 2019.
- Business Quant data shows KRRO's Operating Margin at -1764.86% (Q3 2025), -1863.15% (Q2 2025) and -981.18% (Q1 2025) in the three quarters before Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 37.40% |
| 10 | Korro Bio | 145.73 Mn | -250.91 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -3,900.62% |
| Sep 30, 2025 | -1,764.86% |
| Jun 30, 2025 | -1,863.15% |
| Mar 31, 2025 | -981.18% |
| Dec 31, 2024 | -1,014.53% |
| Jun 30, 2021 | -185.65% |
| Mar 31, 2021 | -434.29% |
| Dec 31, 2020 | -103.29% |
| Sep 30, 2020 | -48.17% |
| Jun 30, 2020 | -72.74% |
| Mar 31, 2020 | -77.85% |
| Dec 31, 2019 | -137.78% |
| Sep 30, 2019 | -5.17% |
API Access
Korro Bio Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=KRRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "KRRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=KRRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();