Korro Bio (KRRO) Operating Margin (2019 - 2025)
Korro Bio (KRRO) posted Operating Margin of 3900.62% for Q4 2025, down 121.02% on a QoQ basis from 1764.86% in Q3 2025, and down 288609.0% year-over-year from N/an in Q4 2024.
Korro Bio (KRRO) Operating Margin (2019 - 2025) Analysis & Trends
Korro Bio's Operating Margin history runs 5 years deep, the most recent figure standing at 3900.62% for Q4 2025.
- Quarterly Operating Margin fell 288609.0% year-over-year to 3900.62% in Q4 2025, while the trailing twelve-month figure through Mar 2026 was 3052.34% (down 107190.0% YoY) and the FY2025 annual result came in at 1906.37%, up 214075.0% from the prior year.
- Operating Margin was 3900.62% for Q4 2025 at Korro Bio, down from 1764.86% in the prior quarter.
- Across five years, Operating Margin topped out at 185.65% in Q2 2021 and bottomed at 3900.62% in Q4 2025.
- A 3-year average of 1449.18% and a median of 1014.53% in 2024 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2021 — Operating Margin tumbled 11291 bps — and 2025, when it plunged 288609 bps.
- Korro Bio's Operating Margin stood at 185.65% in 2021, then plunged by 446 bps to 1014.53% in 2024, then plunged by 284 bps to 3900.62% in 2025.
- Business Quant data shows KRRO's Operating Margin at 3900.62% in Q4 2025, 1764.86% in Q3 2025, and 1863.15% in Q2 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,831.58 Bn | 66,831.30 Bn | - | - |
| 2 | Nanobiotix | 1,916.61 Bn | 1,916.55 Bn | - | - |
| 3 | Akari Therapeutics | 976.78 Bn | 976.78 Bn | - | - |
| 4 | BeOne Medicines | 471.48 Bn | 466.69 Bn | 1.35 Bn | 16.51% |
| 5 | Vertex Pharmaceuticals | 121.78 Bn | 114.53 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 69.87 Bn | 61.12 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 63.06 Bn | 63.06 Bn | - | - |
| 8 | Argenx Se | 55.78 Bn | 50.60 Bn | 1.41 Bn | 31.68% |
| 9 | Alnylam Pharmaceuticals | 37.54 Bn | 34.53 Bn | 959.66 Mn | 23.02% |
| 10 | Korro Bio | 123.47 Mn | 9.50 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3,900.62% |
| Sep 30, 2025 | -1,764.86% |
| Jun 30, 2025 | -1,863.15% |
| Mar 31, 2025 | -981.18% |
| Dec 31, 2024 | -1,014.53% |
| Jun 30, 2021 | -185.65% |
| Mar 31, 2021 | -434.29% |
| Dec 31, 2020 | -103.29% |
| Sep 30, 2020 | -48.17% |
| Jun 30, 2020 | -72.74% |
| Mar 31, 2020 | -77.85% |
| Dec 31, 2019 | -137.78% |
| Sep 30, 2019 | -5.17% |