Korro Bio (KRRO) Operating Margin (2019 - 2025)
Korro Bio's (KRRO) quarterly Operating Margin came in at 3900.62% in Q4 2025, down 288609.0% YoY from N/an in Q4 2024, and down 121.02% on a QoQ basis from 1764.86% in Q3 2025.
Korro Bio (KRRO) Operating Margin (2019 - 2025) Analysis & Trends
Korro Bio (KRRO) has 5 years of Operating Margin data on file, last reported at 3900.62% in Q4 2025.
- Quarterly Operating Margin fell 288609.0% year-over-year to 3900.62% in Q4 2025, while the trailing twelve-month figure through Mar 2026 was 3052.34% (down 107190.0% YoY) and the FY2025 annual result came in at 1906.37%, up 214075.0% from the prior year.
- Operating Margin retreated to 3900.62% in Q4 2025, from 1764.86% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 185.65% in Q2 2021 to a low of 3900.62% in Q4 2025.
- A 3-year average of 1449.18% and a median of 1014.53% in 2024 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2021 — Operating Margin plunged 11291 bps — and 2025, when it sank 288609 bps.
- Tracing KRRO's Operating Margin over 3 years: stood at 185.65% in 2021, then slumped by 446 bps to 1014.53% in 2024, then slumped by 284 bps to 3900.62% in 2025.
- The last three Operating Margin figures came in at 3900.62% (Q4 2025), 1764.86% (Q3 2025), and 1863.15% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 140.29 Bn | 132.43 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 86.58 Bn | 78.58 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 65.26 Bn | 60.08 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 61.87 Bn | 56.73 Bn | 52.00 Mn | -562.07% |
| 5 | BeOne Medicines | 42.18 Bn | 37.08 Bn | 1.53 Bn | 19.06% |
| 6 | Alnylam Pharmaceuticals | 31.51 Bn | 28.20 Bn | 992.69 Mn | 17.93% |
| 7 | BioNTech SE | 28.90 Bn | 10.51 Bn | 668.28 Mn | -35.57% |
| 8 | Insmed | 27.46 Bn | 26.30 Bn | 358.27 Mn | -0.36% |
| 9 | Royalty Pharma | 27.24 Bn | 26.41 Bn | - | 19.75% |
| 10 | Korro Bio | 230.63 Mn | 115.59 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3,900.62% |
| Sep 30, 2025 | -1,764.86% |
| Jun 30, 2025 | -1,863.15% |
| Mar 31, 2025 | -981.18% |
| Dec 31, 2024 | -1,014.53% |
| Jun 30, 2021 | -185.65% |
| Mar 31, 2021 | -434.29% |
| Dec 31, 2020 | -103.29% |
| Sep 30, 2020 | -48.17% |
| Jun 30, 2020 | -72.74% |
| Mar 31, 2020 | -77.85% |
| Dec 31, 2019 | -137.78% |
| Sep 30, 2019 | -5.17% |