Keros Therapeutics (KROS) Operating Margin (2019 - 2025)
Keros Therapeutics' Operating Margin came in at -7602.60% for Q4 2025, down 5851.97 percentage points from -1750.62% a year earlier and down 7494.73 percentage points from the prior quarter.
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Analysis
Keros Therapeutics (KROS) Operating Margin (2019 - 2025) Analysis & Trends
For FY2025, Keros Therapeutics' Operating Margin was 27.69%, up 5966.64 percentage points from FY2024.
- Operating Margin carries a four-year change of +308.15 percentage points (FY2021 to FY2025).
- Going back by year, Operating Margin was -5938.96% in FY2024 (+106604.75 pp), -112543.71% in FY2023 and -280.46% in FY2021.
- The Q4 2025 figure represents the lowest quarterly Operating Margin since Q3 2024.
- Year-over-year, Operating Margin increased in five of the last six quarters, with an average year-over-year change of +126727.21 percentage points.
- Business Quant data shows KROS's Operating Margin at -107.87% (Q3 2025), -219.16% (Q2 2025) and 71.97% (Q1 2025) in the three quarters before Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,134.17 Bn | 1,102.76 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 615.84 Bn | 534.36 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 500.69 Bn | 473.80 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 367.34 Bn | 321.72 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 297.61 Bn | 261.60 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 261.07 Bn | 234.75 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 235.51 Bn | 190.91 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 190.60 Bn | 164.80 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 169.37 Bn | 116.02 Bn | 10.94 Bn | 28.37% |
| 10 | Keros Therapeutics | 221.37 Mn | -1.71 Bn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -7,602.60% |
| Sep 30, 2025 | -107.87% |
| Jun 30, 2025 | -219.16% |
| Mar 31, 2025 | 71.97% |
| Dec 31, 2024 | -1,750.62% |
| Sep 30, 2024 | -15,117.78% |
| Jun 30, 2024 | -136,321.62% |
| Mar 31, 2024 | -58,413.25% |
| Dec 31, 2023 | -32,486.01% |
| Sep 30, 2023 | -541,000.00% |
| Mar 31, 2022 | -134.03% |
| Dec 31, 2021 | -24.33% |
| Jun 30, 2021 | -15,541.00% |
| Dec 31, 2019 | -109.12% |
| Sep 30, 2019 | -93.04% |
| Jun 30, 2019 | -106.04% |
| Mar 31, 2019 | -114.32% |
API Access
Keros Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=KROS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "KROS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=KROS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();