Janux Therapeutics JANX
NASDAQ JANX
$20.24 +0.44 (+2.22%)
As of: Sep 4, 2026 · 3:59 PM EDT

Janux Therapeutics (JANX) Operating Margin (2021 - 2026)

Janux Therapeutics (JANX) posted quarterly Operating Margin of 916.5% for Q1 2026, down 159.99% quarter-over-quarter from 352.51% in Q3 2025.

Analysis

Janux Therapeutics (JANX) Operating Margin (2021 - 2026) Analysis & Trends

Janux Therapeutics (JANX) has reported Operating Margin for 6 consecutive years, with 916.5% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Margin changed N/A year-over-year to 916.5%; the TTM figure through Mar 2026 stood at 1143.11% (up 7351.0% YoY), while the FY2025 annual figure was 1576.67%, down 64309.0% from the prior year.
  • Operating Margin eased to 916.5% in Q1 2026 per JANX's latest filing, from 352.51% in the prior quarter.
  • Across five years, Operating Margin topped out at 155.36% in Q2 2024 and bottomed at 8164.46% in Q3 2024.
  • Historically, Operating Margin has averaged 1434.96% across 5 years, with a median of 852.23% in 2022.
  • Annual changes were most pronounced in 2024 — Operating Margin tumbled 753622 bps — and 2025, when it soared 781195 bps.
  • Janux Therapeutics' Operating Margin stood at 642.04% in 2022, then slipped by 2 bps to 655.71% in 2023, then slumped by 1145 bps to 8164.46% in 2024, then soared by 96 bps to 352.51% in 2025, then slumped by 160 bps to 916.5% in 2026.
  • Business Quant data shows JANX's Operating Margin at 916.5% in Q1 2026, 352.51% in Q3 2025, and 8164.46% in Q3 2024.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 30.15%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 32.54%
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -562.07%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 19.06%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 17.93%
8 Royalty Pharma 28.45 Bn 27.61 Bn - 19.75%
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -0.36%
10 Janux Therapeutics 1.27 Bn 1.27 Bn - -308.66%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -308.66%
Mar 31, 2026 -916.50%
Sep 30, 2025 -352.51%
Sep 30, 2024 -8,164.46%
Jun 30, 2024 -155.36%
Mar 31, 2024 -1,610.30%
Dec 31, 2023 -655.71%
Sep 30, 2023 -628.25%
Jun 30, 2023 -1,962.91%
Mar 31, 2023 -990.28%
Dec 31, 2022 -642.04%
Sep 30, 2022 -994.04%
Jun 30, 2022 -729.85%
Mar 31, 2022 -852.23%
Dec 31, 2021 -834.78%
Sep 30, 2021 -940.72%
Jun 30, 2021 -1,297.10%
Mar 31, 2021 -601.05%