Janux Therapeutics (JANX) Operating Margin (2021 - 2026)
Janux Therapeutics (JANX) reported Operating Margin of 916.5% for Q1 2026, down 159.99% on a QoQ basis from 352.51% in Q3 2025.
Janux Therapeutics (JANX) has 6 years of Operating Margin data on file, last reported at 916.5% in Q1 2026.
- Quarterly Operating Margin changed N/A year-over-year to 916.5% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 1143.11% (up 7351.0% YoY) and the FY2025 annual result came in at 1576.67%, down 64309.0% from the prior year.
- Operating Margin retreated to 916.5% in Q1 2026 per JANX's latest filing, from 352.51% in the prior quarter.
- Across five years, Operating Margin topped out at 155.36% in Q2 2024 and bottomed at 8164.46% in Q3 2024.
- The 5-year median for Operating Margin is 852.23% (2022), against an average of 1434.96%.
- The widest annual swing landed in 2024, when Operating Margin sank 753622 bps; it then jumped 781195 bps in 2025.
- Tracing JANX's Operating Margin over 5 years: stood at 642.04% in 2022, then fell by 2 bps to 655.71% in 2023, then tumbled by 1145 bps to 8164.46% in 2024, then soared by 96 bps to 352.51% in 2025, then tumbled by 160 bps to 916.5% in 2026.
- Per Business Quant, the three latest JANX Operating Margin figures stand at 916.5% (Q1 2026), 352.51% (Q3 2025), and 8164.46% (Q3 2024).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 17.83% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 23.02% |
| 10 | Janux Therapeutics | 914.29 Mn | 914.29 Mn | - | -916.50% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -916.50% |
| Sep 30, 2025 | -352.51% |
| Sep 30, 2024 | -8,164.46% |
| Jun 30, 2024 | -155.36% |
| Mar 31, 2024 | -1,610.30% |
| Dec 31, 2023 | -655.71% |
| Sep 30, 2023 | -628.25% |
| Jun 30, 2023 | -1,962.91% |
| Mar 31, 2023 | -990.28% |
| Dec 31, 2022 | -642.04% |
| Sep 30, 2022 | -994.04% |
| Jun 30, 2022 | -729.85% |
| Mar 31, 2022 | -852.23% |
| Dec 31, 2021 | -834.78% |
| Sep 30, 2021 | -940.72% |
| Jun 30, 2021 | -1,297.10% |
| Mar 31, 2021 | -601.05% |