Janux Therapeutics (JANX) Operating Margin (2021 - 2026)

Janux Therapeutics' (JANX) quarterly Operating Margin came in at 916.5% in Q1 2026, down 159.99% on a QoQ basis from 352.51% in Q3 2025.

Janux Therapeutics (JANX) Operating Margin (2021 - 2026) Analysis & Trends

Janux Therapeutics (JANX) has 6 years of Operating Margin data on file, last reported at 916.5% in Q1 2026.

  • On a quarterly basis, Operating Margin changed N/A year-over-year to 916.5% in Q1 2026; TTM through Mar 2026 was 1143.11%, a 7351.0% increase from a year earlier, with the FY2025 full-year figure at 1576.67%, down 64309.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 916.5%, down from 352.51% in the prior quarter.
  • Over the last five years, Operating Margin for JANX reached as high as 155.36% in Q2 2024 and fell as low as 8164.46% in Q3 2024.
  • Historically, Operating Margin has averaged 1434.96% across 5 years, with a median of 852.23% in 2022.
  • Across the five-year window, Operating Margin sank 753622 bps in 2024 and jumped 781195 bps in 2025, its largest moves.
  • Year by year, Operating Margin stood at 642.04% in 2022, then declined by 2 bps to 655.71% in 2023, then slumped by 1145 bps to 8164.46% in 2024, then surged by 96 bps to 352.51% in 2025, then slumped by 160 bps to 916.5% in 2026.
  • Per Business Quant data, the three most recent Operating Margin figures were 916.5% in Q1 2026, 352.51% in Q3 2025, and 8164.46% in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Janux Therapeutics 985.11 Mn 985.11 Mn - -916.50%

Historic Data

Download Data
DateValue
Mar 31, 2026 -916.50%
Sep 30, 2025 -352.51%
Sep 30, 2024 -8,164.46%
Jun 30, 2024 -155.36%
Mar 31, 2024 -1,610.30%
Dec 31, 2023 -655.71%
Sep 30, 2023 -628.25%
Jun 30, 2023 -1,962.91%
Mar 31, 2023 -990.28%
Dec 31, 2022 -642.04%
Sep 30, 2022 -994.04%
Jun 30, 2022 -729.85%
Mar 31, 2022 -852.23%
Dec 31, 2021 -834.78%
Sep 30, 2021 -940.72%
Jun 30, 2021 -1,297.10%
Mar 31, 2021 -601.05%