Growth Metrics

Invivyd (IVVD) Operating Margin (2024 - 2025)

Invivyd posted quarterly Operating Margin of 72.96% for Q4 2025, up 6617.0% year-on-year from 1.09% in Q4 2024, and up 13.1% on a QoQ basis from 83.96% in Q3 2025.

Invivyd (IVVD) has 2 years of Operating Margin data on file, last reported at 72.96% in Q4 2025.

  • For the quarter ending Q4 2025, Operating Margin rose 6617.0% year-over-year to 72.96%; the trailing twelve-month figure through Dec 2025 stood at 103.99% (up 59281.0% YoY), and the FY2025 full-year result was 103.99%, up 59281.0% from the prior year.
  • Operating Margin for Q4 2025 stood at 72.96%, up from 83.96% in the prior quarter.
  • Across five years, Operating Margin topped out at 72.96% in Q4 2025 and bottomed at 2175.22% in Q2 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Invivyd 208.38 Mn -18.31 Mn - -72.96%

Historic Data

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DateValue
Dec 31, 2025 -72.96%
Sep 30, 2025 -83.96%
Jun 30, 2025 -127.78%
Mar 31, 2025 -149.70%
Dec 31, 2024 -139.14%
Sep 30, 2024 -670.01%
Jun 30, 2024 -2,175.22%