Immatics (IMTX) Operating Margin (2019 - 2025)
Immatics' (IMTX) quarterly Operating Margin came in at 196.76% in Q4 2025, down 19948.0% year-on-year from N/an in Q4 2024, and up 81.32% quarter-over-quarter from 1053.27% in Q3 2025.
Immatics (IMTX) Operating Margin (2019 - 2025) Analysis & Trends
Immatics has disclosed Operating Margin across 7 years of filings, most recently posting 196.76% for Q4 2025.
- Operating Margin for Q4 2025 came in at 196.76%, down 19948.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 382.54% (down 34514.0% YoY), and the FY2025 annual result was 377.11%, down 35233.0% from the prior year.
- Operating Margin came in at 196.76% for Q4 2025 at Immatics, up from 1053.27% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 66.56% in Q1 2022 to a low of 1121.53% in Q2 2025.
- The 5-year median for Operating Margin is 159.83% (2022), against an average of 260.99%.
- Across the five-year window, Operating Margin surged 56382 bps in 2024 and slumped 105572 bps in 2025, its largest moves.
- Immatics' Operating Margin stood at 102.12% in 2021, then jumped by 100 bps to 0.12% in 2022, then tumbled by 145732 bps to 174.07% in 2023, then jumped by 102 bps to 2.73% in 2024, then tumbled by 7312 bps to 196.76% in 2025.
- The last three Operating Margin figures came in at 196.76% (Q4 2025), 1053.27% (Q3 2025), and 1121.53% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Immatics | 14.67 Bn | 14.67 Bn | - | -196.76% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -196.76% |
| Sep 30, 2025 | -1,053.27% |
| Jun 30, 2025 | -1,121.53% |
| Mar 31, 2025 | -190.37% |
| Dec 31, 2024 | 2.73% |
| Sep 30, 2024 | 2.45% |
| Jun 30, 2024 | -141.64% |
| Mar 31, 2024 | -44.50% |
| Dec 31, 2023 | -174.07% |
| Sep 30, 2023 | -561.37% |
| Jun 30, 2023 | -64.04% |
| Mar 31, 2023 | -269.80% |
| Dec 31, 2022 | 0.12% |
| Sep 30, 2022 | -145.58% |
| Jun 30, 2022 | -96.76% |
| Mar 31, 2022 | 66.56% |
| Dec 31, 2021 | -102.12% |
| Sep 30, 2021 | -356.99% |
| Jun 30, 2021 | -450.88% |
| Mar 31, 2021 | -322.00% |