Immunome (IMNM) Operating Margin (2023 - 2025)

Immunome (IMNM) posted Operating Margin of 1157.61% for Q2 2025, up 24.12% on a QoQ basis from 1525.5% in Q1 2025, and up 53482.0% year-over-year from N/an in Q2 2024.

Immunome (IMNM) Operating Margin (2023 - 2025) Analysis & Trends

Immunome's Operating Margin history runs 3 years deep, the most recent figure standing at 1157.61% for Q2 2025.

  • Quarterly Operating Margin rose 53482.0% year-over-year to 1157.61% in Q2 2025, while the trailing twelve-month figure through Mar 2026 was 5947.9% (down 395359.0% YoY) and the FY2025 annual result came in at 3228.83%, up 15354.0% from the prior year.
  • Operating Margin was 1157.61% for Q2 2025 at Immunome, up from 1525.5% in the prior quarter.
  • Across five years, Operating Margin topped out at 129.96% in Q3 2023 and bottomed at 12857.05% in Q1 2024.
  • A 3-year average of 2492.75% and a median of 1608.96% in 2025 frame the typical range for Operating Margin.
  • Annual changes were most pronounced in 2024 — Operating Margin tumbled 1266792 bps — and 2025, when it surged 1133155 bps.
  • Immunome's Operating Margin stood at 2473.94% in 2023, then dropped by 22 bps to 3030.31% in 2024, then surged by 62 bps to 1157.61% in 2025.
  • Business Quant data shows IMNM's Operating Margin at 1157.61% in Q2 2025, 1525.5% in Q1 2025, and 3030.31% in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 17.83%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 30.35%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Immunome 2.51 Bn 1.93 Bn - -

Historic Data

Download Data
DateValue
Jun 30, 2025 -1,157.61%
Mar 31, 2025 -1,525.50%
Dec 31, 2024 -3,030.31%
Sep 30, 2024 -1,736.15%
Jun 30, 2024 -1,692.43%
Mar 31, 2024 -12,857.05%
Dec 31, 2023 -2,473.94%
Sep 30, 2023 -129.96%
Jun 30, 2023 -135.42%
Mar 31, 2023 -189.13%