Harmony Biosciences Holdings (HRMY) Operating Margin (2020 - 2026)

Harmony Biosciences Holdings' (HRMY) quarterly Operating Margin came in at 3.87% in Q1 2026, down 2658.0% year-on-year from 0.15% in Q1 2025, and up 107.56% quarter-over-quarter from 51.17% in Q4 2025.

Harmony Biosciences Holdings (HRMY) Operating Margin (2020 - 2026) Analysis & Trends

Harmony Biosciences Holdings has disclosed Operating Margin across 7 years of filings, most recently posting 3.87% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 3.87%, down 2658.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.31% (down 2649.0% YoY), and the FY2025 annual result was 5.2%, down 2150.0% from the prior year.
  • Operating Margin came in at 3.87% for Q1 2026 at Harmony Biosciences Holdings, up from 51.17% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 40.25% in Q3 2023 to a low of 51.17% in Q4 2025.
  • The 5-year median for Operating Margin is 30.45% (2025), against an average of 22.64%.
  • Across the five-year window, Operating Margin soared 3010 bps in 2023 and sank 7886 bps in 2025, its largest moves.
  • Harmony Biosciences Holdings' Operating Margin stood at 37.11% in 2022, then sank by 36 bps to 23.87% in 2023, then advanced by 16 bps to 27.69% in 2024, then slumped by 285 bps to 51.17% in 2025, then soared by 108 bps to 3.87% in 2026.
  • The last three Operating Margin figures came in at 3.87% (Q1 2026), 51.17% (Q4 2025), and 27.35% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Harmony Biosciences Holdings 1.92 Bn 1.28 Bn 170.88 Mn 3.87%

Historic Data

Download Data
DateValue
Mar 31, 2026 3.87%
Dec 31, 2025 -51.17%
Sep 30, 2025 27.35%
Jun 30, 2025 24.03%
Mar 31, 2025 30.45%
Dec 31, 2024 27.69%
Sep 30, 2024 33.17%
Jun 30, 2024 12.36%
Mar 31, 2024 33.65%
Dec 31, 2023 23.87%
Sep 30, 2023 40.25%
Jun 30, 2023 34.95%
Mar 31, 2023 33.93%
Dec 31, 2022 37.11%
Sep 30, 2022 10.15%
Jun 30, 2022 30.94%
Mar 31, 2022 32.30%
Dec 31, 2021 31.39%
Sep 30, 2021 26.08%
Jun 30, 2021 31.58%