Harmony Biosciences Holdings (HRMY) Operating Margin (2020 - 2026)
Harmony Biosciences Holdings' (HRMY) quarterly Operating Margin came in at 3.87% in Q1 2026, down 2658.0% year-on-year from 0.15% in Q1 2025, and up 107.56% quarter-over-quarter from 51.17% in Q4 2025.
Harmony Biosciences Holdings (HRMY) Operating Margin (2020 - 2026) Analysis & Trends
Harmony Biosciences Holdings has disclosed Operating Margin across 7 years of filings, most recently posting 3.87% for Q1 2026.
- Operating Margin for Q1 2026 came in at 3.87%, down 2658.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.31% (down 2649.0% YoY), and the FY2025 annual result was 5.2%, down 2150.0% from the prior year.
- Operating Margin came in at 3.87% for Q1 2026 at Harmony Biosciences Holdings, up from 51.17% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 40.25% in Q3 2023 to a low of 51.17% in Q4 2025.
- The 5-year median for Operating Margin is 30.45% (2025), against an average of 22.64%.
- Across the five-year window, Operating Margin soared 3010 bps in 2023 and sank 7886 bps in 2025, its largest moves.
- Harmony Biosciences Holdings' Operating Margin stood at 37.11% in 2022, then sank by 36 bps to 23.87% in 2023, then advanced by 16 bps to 27.69% in 2024, then slumped by 285 bps to 51.17% in 2025, then soared by 108 bps to 3.87% in 2026.
- The last three Operating Margin figures came in at 3.87% (Q1 2026), 51.17% (Q4 2025), and 27.35% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Harmony Biosciences Holdings | 1.92 Bn | 1.28 Bn | 170.88 Mn | 3.87% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 3.87% |
| Dec 31, 2025 | -51.17% |
| Sep 30, 2025 | 27.35% |
| Jun 30, 2025 | 24.03% |
| Mar 31, 2025 | 30.45% |
| Dec 31, 2024 | 27.69% |
| Sep 30, 2024 | 33.17% |
| Jun 30, 2024 | 12.36% |
| Mar 31, 2024 | 33.65% |
| Dec 31, 2023 | 23.87% |
| Sep 30, 2023 | 40.25% |
| Jun 30, 2023 | 34.95% |
| Mar 31, 2023 | 33.93% |
| Dec 31, 2022 | 37.11% |
| Sep 30, 2022 | 10.15% |
| Jun 30, 2022 | 30.94% |
| Mar 31, 2022 | 32.30% |
| Dec 31, 2021 | 31.39% |
| Sep 30, 2021 | 26.08% |
| Jun 30, 2021 | 31.58% |