Gyre Therapeutics (GYRE) Operating Margin (2010 - 2026)
Gyre Therapeutics' Operating Margin was -49.35% in Q2 2026, down 41.82 percentage points from -7.53% a year earlier and down 7.81 percentage points from the prior quarter.
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Analysis
Gyre Therapeutics (GYRE) Operating Margin (2010 - 2026) Analysis & Trends
On a trailing twelve-month basis, Gyre Therapeutics' Operating Margin was -13.97% through Jun 30, 2026, down 18.66 percentage points year-over-year; for FY2025, it came in at 9.85%, down 5.43 percentage points from FY2024.
- Operating Margin shows a five-year change of +283.72 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was 15.28% in FY2024 (+74.54 pp), -59.26% in FY2023 (-68.26 pp), 9.00% in FY2022 (+1206.79 pp) and -1197.79% in FY2021 (-923.92 pp).
- The Q2 2026 figure marks the lowest quarterly Operating Margin since Q4 2023.
- Compared with a year earlier, Operating Margin has declined for three straight quarters, with an average year-over-year change of +23.43 percentage points over the last eight quarters.
- The best year-over-year quarter for Operating Margin over five years was Q1 2023 (a gain of 1878.24 percentage points); the worst was Q1 2022 (a drop of 322.00 percentage points).
- Per Business Quant data, GYRE's Operating Margin in the three quarters before Q2 2026 was -41.54% (Q1 2026), 0.32% (Q4 2025) and 22.66% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 37.40% |
| 10 | Gyre Therapeutics | 777.23 Mn | 579.94 Mn | 26.90 Mn | -49.35% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -49.35% |
| Mar 31, 2026 | -41.54% |
| Dec 31, 2025 | 0.32% |
| Sep 30, 2025 | 22.66% |
| Jun 30, 2025 | -7.53% |
| Mar 31, 2025 | 10.30% |
| Dec 31, 2024 | 2.39% |
| Sep 30, 2024 | 16.61% |
| Jun 30, 2024 | 12.66% |
| Mar 31, 2024 | 29.70% |
| Dec 31, 2023 | -337.53% |
| Sep 30, 2023 | 39.84% |
| Jun 30, 2023 | 16.96% |
| Mar 31, 2023 | 26.73% |
| Dec 31, 2022 | -22.13% |
| Mar 31, 2022 | -1,851.51% |
| Dec 31, 2021 | -832.50% |
| Sep 30, 2021 | -1,097.39% |
| Jun 30, 2021 | -1,759.19% |
| Mar 31, 2021 | -1,529.52% |
API Access
Gyre Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=GYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "GYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=GYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();