Precision Biosciences (DTIL) Operating Margin (2018 - 2026)

Precision Biosciences (DTIL) reported Operating Margin of 83.73% for Q1 2026, up 7616454.0% year-over-year from N/an in Q1 2025, and down 328.97% quarter-over-quarter from 36.57% in Q4 2025.

Precision Biosciences (DTIL) Operating Margin (2018 - 2026) Analysis & Trends

Precision Biosciences (DTIL) has 9 years of Operating Margin data on file, last reported at 83.73% in Q1 2026.

  • Operating Margin for Q1 2026 came in at 83.73%, up 7616454.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 86.77% (down 57.0% YoY), and the FY2025 annual result was 152.19%, down 11411.0% from the prior year.
  • Operating Margin retreated to 83.73% in Q1 2026 per DTIL's latest filing, from 36.57% in the prior quarter.
  • Over five years, Operating Margin peaked at 48.39% in Q2 2024 and troughed at 158976.92% in Q3 2025.
  • A 5-year average of 21574.1% and a median of 199.32% in 2022 frame the typical range for Operating Margin.
  • The sharpest annual moves came in 2025 and 2026: Operating Margin sank 15528335 bps in 2025, then soared 7616454 bps in 2026.
  • A 5-year view of Operating Margin shows it stood at 114.26% in 2022, then slumped by 85 bps to 211.57% in 2023, then tumbled by 1741 bps to 3894.36% in 2024, then soared by 101 bps to 36.57% in 2025, then tumbled by 329 bps to 83.73% in 2026.
  • Business Quant data shows DTIL's Operating Margin at 83.73% in Q1 2026, 36.57% in Q4 2025, and 158976.92% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Precision Biosciences 168.99 Mn 67.81 Mn - -83.73%

Historic Data

Download Data
DateValue
Mar 31, 2026 -83.73%
Dec 31, 2025 36.57%
Sep 30, 2025 -158,976.92%
Jun 30, 2025 -121,538.89%
Mar 31, 2025 -76,248.28%
Dec 31, 2024 -3,894.36%
Sep 30, 2024 -3,693.58%
Jun 30, 2024 48.39%
Mar 31, 2024 -23.81%
Dec 31, 2023 -211.57%
Sep 30, 2023 -94.23%
Jun 30, 2023 -15.81%
Mar 31, 2023 -152.10%
Dec 31, 2022 -114.26%
Sep 30, 2022 -199.32%
Jun 30, 2022 -773.66%
Mar 31, 2022 -824.09%
Dec 31, 2021 -484.68%
Sep 30, 2021 -48.02%
Jun 30, 2021 31.44%