Precision Biosciences (DTIL) Operating Margin (2018 - 2026)

Precision Biosciences' (DTIL) quarterly Operating Margin came in at 83.73% in Q1 2026, up 7616454.0% year-on-year from N/an in Q1 2025, and down 328.97% on a QoQ basis from 36.57% in Q4 2025.

Precision Biosciences (DTIL) Operating Margin (2018 - 2026) Analysis & Trends

Precision Biosciences (DTIL) has 9 years of Operating Margin data on file, last reported at 83.73% in Q1 2026.

  • On a quarterly basis, Operating Margin rose 7616454.0% year-over-year to 83.73% in Q1 2026; TTM through Mar 2026 was 86.77%, a 57.0% decrease from a year earlier, with the FY2025 full-year figure at 152.19%, down 11411.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 83.73%, down from 36.57% in the prior quarter.
  • Over the last five years, Operating Margin for DTIL reached as high as 48.39% in Q2 2024 and fell as low as 158976.92% in Q3 2025.
  • Historically, Operating Margin has averaged 21574.1% across 5 years, with a median of 199.32% in 2022.
  • Across the five-year window, Operating Margin tumbled 15528335 bps in 2025 and jumped 7616454 bps in 2026, its largest moves.
  • Year by year, Operating Margin stood at 114.26% in 2022, then tumbled by 85 bps to 211.57% in 2023, then plunged by 1741 bps to 3894.36% in 2024, then soared by 101 bps to 36.57% in 2025, then plunged by 329 bps to 83.73% in 2026.
  • Per Business Quant data, the three most recent Operating Margin figures were 83.73% in Q1 2026, 36.57% in Q4 2025, and 158976.92% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 65,899.61 Bn 65,899.33 Bn - -
2 Nanobiotix 1,933.82 Bn 1,933.76 Bn - -
3 Akari Therapeutics 1,022.34 Bn 1,022.34 Bn - -
4 BeOne Medicines 472.68 Bn 467.89 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 122.24 Bn 114.99 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 70.08 Bn 61.33 Bn 3.31 Bn 17.83%
7 Belite Bio 62.46 Bn 62.46 Bn - -
8 Argenx Se 55.93 Bn 50.75 Bn 1.41 Bn 31.68%
9 Alnylam Pharmaceuticals 37.59 Bn 34.58 Bn 959.66 Mn 23.02%
10 Precision Biosciences 185.13 Mn 156.84 Mn - -83.73%

Historic Data

Download Data
DateValue
Mar 31, 2026 -83.73%
Dec 31, 2025 36.57%
Sep 30, 2025 -158,976.92%
Jun 30, 2025 -121,538.89%
Mar 31, 2025 -76,248.28%
Dec 31, 2024 -3,894.36%
Sep 30, 2024 -3,693.58%
Jun 30, 2024 48.39%
Mar 31, 2024 -23.81%
Dec 31, 2023 -211.57%
Sep 30, 2023 -94.23%
Jun 30, 2023 -15.81%
Mar 31, 2023 -152.10%
Dec 31, 2022 -114.26%
Sep 30, 2022 -199.32%
Jun 30, 2022 -773.66%
Mar 31, 2022 -824.09%
Dec 31, 2021 -484.68%
Sep 30, 2021 -48.02%
Jun 30, 2021 31.44%