Dianthus Therapeutics (DNTH) Operating Margin (2022 - 2025)
Dianthus Therapeutics' Operating Margin came in at -10173.74% for Q3 2025, down 8797.13 percentage points from -1376.61% a year earlier but up 7923.15 percentage points from the prior quarter.
Dianthus Therapeutics (DNTH) Operating Margin (2022 - 2025) Analysis & Trends
Over the trailing twelve months to Sep 30, 2025, Dianthus Therapeutics reported Operating Margin of -4558.41%, down 3013.43 percentage points year-over-year; for FY2024, it came in at -1633.74%, up 70.93 percentage points from FY2023.
- Going back by year, Operating Margin was -1704.67% in FY2023 (-1472.91 pp) and -231.76% in FY2022.
- The five-year range for quarterly Operating Margin is -18096.89% (Q2 2025) to -141.16% (Q4 2022).
- Year-over-year, Operating Margin has declined for three consecutive quarters, with an average year-over-year change of -3787.29 percentage points over the last eight quarters.
- The fastest year-over-year change in Operating Margin over five years came in Q4 2024 (a gain of 428.07 percentage points), and the weakest in Q2 2025 (a drop of 16905.05 percentage points).
- Business Quant data shows DNTH's Operating Margin at -18096.89% (Q2 2025), -2852.71% (Q1 2025) and -2406.94% (Q4 2024) in the three quarters before Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Dianthus Therapeutics | 3.76 Bn | 3.71 Bn | - | - |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -10,173.74% |
| Jun 30, 2025 | -18,096.89% |
| Mar 31, 2025 | -2,852.71% |
| Dec 31, 2024 | -2,406.94% |
| Sep 30, 2024 | -1,376.61% |
| Jun 30, 2024 | -1,191.84% |
| Mar 31, 2024 | -2,041.65% |
| Dec 31, 2023 | -2,835.01% |
| Sep 30, 2023 | -1,705.52% |
| Jun 30, 2023 | -598.07% |
| Mar 31, 2023 | -787.19% |
| Dec 31, 2022 | -141.16% |
| Sep 30, 2022 | -703.67% |
Dianthus Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=DNTH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "DNTH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=DNTH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();