Cue Biopharma (CUE) Operating Margin (2018 - 2026)
Cue Biopharma (CUE) recorded Operating Margin of -1113.30% in Q2 2026, down 820.99 percentage points from -292.32% a year earlier.
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Analysis
Cue Biopharma (CUE) Operating Margin (2018 - 2026) Analysis & Trends
On a TTM basis, Cue Biopharma's Operating Margin came in at -291.93% as of Jun 30, 2026, up 183.30 percentage points year-over-year; for FY2025, it was -96.67%, up 350.19 percentage points from FY2024.
- Annual Operating Margin has increased for three straight years, with a five-year change of +1331.29 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -446.86% in FY2024 (+503.03 pp), -949.89% in FY2023 (+3325.21 pp), -4275.10% in FY2022 (-3982.54 pp) and -292.56% in FY2021 (+1135.41 pp).
- The Q2 2026 figure is the lowest quarterly Operating Margin since Q1 2025.
- On a year-over-year basis, Operating Margin rose in four of the last seven quarters, with an average year-over-year change of -278.19 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 49368.08 percentage points in Q2 2023, against a drop of 49969.99 percentage points in Q2 2022 at the low end.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 28.37% |
| 10 | Cue Biopharma | 121.14 Mn | 30.41 Mn | - | -1,113.30% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,113.30% |
| Dec 31, 2025 | 9.01% |
| Sep 30, 2025 | -353.42% |
| Jun 30, 2025 | -292.32% |
| Mar 31, 2025 | -2,921.38% |
| Dec 31, 2024 | -611.23% |
| Sep 30, 2024 | -264.24% |
| Jun 30, 2024 | -390.63% |
| Mar 31, 2024 | -737.80% |
| Dec 31, 2023 | -759.58% |
| Sep 30, 2023 | -543.76% |
| Jun 30, 2023 | -978.08% |
| Mar 31, 2023 | -7,155.08% |
| Dec 31, 2022 | -9,845.03% |
| Sep 30, 2022 | -16,222.06% |
| Jun 30, 2022 | -50,346.15% |
| Mar 31, 2022 | -1,423.80% |
| Dec 31, 2021 | -95.62% |
| Sep 30, 2021 | -543.55% |
| Jun 30, 2021 | -376.16% |
API Access
Cue Biopharma Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CUE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CUE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CUE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();