Growth Metrics

Cue Biopharma (CUE) Operating Margin (2018 - 2025)

Cue Biopharma (CUE) has disclosed Operating Margin for 8 consecutive years, with 242.62% as the latest value for Q4 2025.

  • Quarterly Operating Margin fell 123746.0% to 242.62% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 36.47% through Dec 2025, up 5548.0% year-over-year, with the annual reading at 19.96% for FY2025, 7201.0% up from the prior year.
  • Operating Margin hit 242.62% in Q4 2025 for Cue Biopharma, up from 353.42% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 1480.08% in Q4 2024 to a low of 50346.15% in Q2 2022.
  • Historically, Operating Margin has averaged 4616.6% across 5 years, with a median of 640.78% in 2023.
  • Biggest five-year swings in Operating Margin: crashed -4996999bps in 2022 and later skyrocketed 4936808bps in 2023.
  • Year by year, Operating Margin stood at 95.62% in 2021, then tumbled by -10196bps to 9845.03% in 2022, then surged by 92bps to 759.58% in 2023, then skyrocketed by 295bps to 1480.08% in 2024, then tumbled by -84bps to 242.62% in 2025.
  • Business Quant data shows Operating Margin for CUE at 242.62% in Q4 2025, 353.42% in Q3 2025, and 292.32% in Q2 2025.