CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026)
CRISPR Therapeutics AG's (CRSP) quarterly Operating Margin came in at 8933.33% in Q1 2026, up 822551.0% year-on-year from N/an in Q1 2025, and up 50.13% quarter-over-quarter from 17912.5% in Q4 2025.
CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026) Analysis & Trends
CRISPR Therapeutics AG has disclosed Operating Margin across 11 years of filings, most recently posting 8933.33% for Q1 2026.
- Operating Margin for Q1 2026 came in at 8933.33%, up 822551.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 15754.2% (down 1449501.0% YoY), and the FY2025 annual result was 18933.65%, down 1768327.0% from the prior year.
- Operating Margin came in at 8933.33% for Q1 2026 at CRISPR Therapeutics AG, up from 17912.5% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 34.58% in Q4 2023 to a low of 2192350.0% in Q4 2022.
- The 5-year median for Operating Margin is 18103.26% (2024), against an average of 167590.53%.
- Across the five-year window, Operating Margin slumped 219122047 bps in 2022 and jumped 219238458 bps in 2023, its largest moves.
- CRISPR Therapeutics AG's Operating Margin stood at 2192350.0% in 2022, then surged by 100 bps to 34.58% in 2023, then slumped by 623 bps to 180.96% in 2024, then tumbled by 9798 bps to 17912.5% in 2025, then jumped by 50 bps to 8933.33% in 2026.
- The last three Operating Margin figures came in at 8933.33% (Q1 2026), 17912.5% (Q4 2025), and 14854.78% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | CRISPR Therapeutics AG | 5.21 Bn | 2.76 Bn | - | -8,933.33% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -8,933.33% |
| Dec 31, 2025 | -17,912.50% |
| Sep 30, 2025 | -14,854.78% |
| Jun 30, 2025 | -25,708.97% |
| Mar 31, 2025 | -17,158.84% |
| Dec 31, 2024 | -180.96% |
| Sep 30, 2024 | -18,294.02% |
| Jun 30, 2024 | -29,257.25% |
| Mar 31, 2024 | -27,894.25% |
| Dec 31, 2023 | 34.58% |
| Jun 30, 2023 | -136.03% |
| Mar 31, 2023 | -64.49% |
| Dec 31, 2022 | -2,192,350.00% |
| Sep 30, 2022 | -194,029.79% |
| Jun 30, 2022 | -115,987.34% |
| Mar 31, 2022 | -18,720.43% |
| Dec 31, 2021 | -1,129.53% |
| Sep 30, 2021 | -15,637.01% |
| Jun 30, 2021 | 84.67% |
| Mar 31, 2021 | -21,251.02% |