CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026)
CRISPR Therapeutics AG (CRSP) recorded Operating Margin of -1151.84% in Q2 2026, up 24557.13 percentage points from -25708.97% a year earlier and up 7781.49 percentage points from the prior quarter.
CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026) Analysis & Trends
On a TTM basis, CRISPR Therapeutics AG's Operating Margin came in at -3989.99% as of Jun 30, 2026, down 2538.05 percentage points year-over-year; for FY2025, it was -18933.65%, down 17683.27 percentage points from FY2024.
- Annual Operating Margin has a five-year change of +30361.90 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -1250.38% in FY2024 (-1190.43 pp), -59.95% in FY2023 (+56130.45 pp), -56190.40% in FY2022 (-56231.23 pp) and 40.82% in FY2021 (+49336.37 pp).
- The Q2 2026 figure is the highest quarterly Operating Margin since Q4 2024.
- On a year-over-year basis, Operating Margin rose in five of the last seven quarters, with an average year-over-year change of +4651.21 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 2192384.58 percentage points in Q4 2023, against a drop of 2191220.47 percentage points in Q4 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -8933.33% (Q1 2026), -17912.50% (Q4 2025) and -14854.78% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | CRISPR Therapeutics AG | 5.23 Bn | 5.23 Bn | - | -1,151.84% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,151.84% |
| Mar 31, 2026 | -8,933.33% |
| Dec 31, 2025 | -17,912.50% |
| Sep 30, 2025 | -14,854.78% |
| Jun 30, 2025 | -25,708.97% |
| Mar 31, 2025 | -17,158.84% |
| Dec 31, 2024 | -180.96% |
| Sep 30, 2024 | -18,294.02% |
| Jun 30, 2024 | -29,257.25% |
| Mar 31, 2024 | -27,894.25% |
| Dec 31, 2023 | 34.58% |
| Jun 30, 2023 | -136.03% |
| Mar 31, 2023 | -64.49% |
| Dec 31, 2022 | -2,192,350.00% |
| Sep 30, 2022 | -194,029.79% |
| Jun 30, 2022 | -115,987.34% |
| Mar 31, 2022 | -18,720.43% |
| Dec 31, 2021 | -1,129.53% |
| Sep 30, 2021 | -15,637.01% |
| Jun 30, 2021 | 84.67% |
CRISPR Therapeutics AG Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CRSP&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CRSP", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CRSP&period=max&api_key=YOUR_API_KEY");
const data = await res.json();