CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026)

CRISPR Therapeutics AG (CRSP) reported Operating Margin of 8933.33% for Q1 2026, up 822551.0% on a YoY basis from N/an in Q1 2025, and up 50.13% sequentially from 17912.5% in Q4 2025.

CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026) Analysis & Trends

CRISPR Therapeutics AG (CRSP) has 11 years of Operating Margin data on file, last reported at 8933.33% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin rose 822551.0% year-over-year to 8933.33%; the trailing twelve-month figure through Mar 2026 stood at 15754.2% (down 1449501.0% YoY), and the FY2025 full-year result was 18933.65%, down 1768327.0% from the prior year.
  • Operating Margin advanced to 8933.33% in Q1 2026, from 17912.5% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 34.58% in Q4 2023 to a low of 2192350.0% in Q4 2022.
  • A 5-year average of 167590.53% and a median of 18103.26% in 2024 frame the typical range for Operating Margin.
  • Across the five-year window, Operating Margin plunged 219122047 bps in 2022 and jumped 219238458 bps in 2023, its largest moves.
  • Tracing CRSP's Operating Margin over 5 years: stood at 2192350.0% in 2022, then jumped by 100 bps to 34.58% in 2023, then tumbled by 623 bps to 180.96% in 2024, then plunged by 9798 bps to 17912.5% in 2025, then soared by 50 bps to 8933.33% in 2026.
  • Business Quant data shows CRSP's Operating Margin at 8933.33% in Q1 2026, 17912.5% in Q4 2025, and 14854.78% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 CRISPR Therapeutics AG 4.57 Bn 2.12 Bn - -8,933.33%

Historic Data

Download Data
DateValue
Mar 31, 2026 -8,933.33%
Dec 31, 2025 -17,912.50%
Sep 30, 2025 -14,854.78%
Jun 30, 2025 -25,708.97%
Mar 31, 2025 -17,158.84%
Dec 31, 2024 -180.96%
Sep 30, 2024 -18,294.02%
Jun 30, 2024 -29,257.25%
Mar 31, 2024 -27,894.25%
Dec 31, 2023 34.58%
Jun 30, 2023 -136.03%
Mar 31, 2023 -64.49%
Dec 31, 2022 -2,192,350.00%
Sep 30, 2022 -194,029.79%
Jun 30, 2022 -115,987.34%
Mar 31, 2022 -18,720.43%
Dec 31, 2021 -1,129.53%
Sep 30, 2021 -15,637.01%
Jun 30, 2021 84.67%
Mar 31, 2021 -21,251.02%