CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026)

CRISPR Therapeutics AG's (CRSP) quarterly Operating Margin came in at 8933.33% in Q1 2026, up 822551.0% year-on-year from N/an in Q1 2025, and up 50.13% quarter-over-quarter from 17912.5% in Q4 2025.

CRISPR Therapeutics AG (CRSP) Operating Margin (2016 - 2026) Analysis & Trends

CRISPR Therapeutics AG has disclosed Operating Margin across 11 years of filings, most recently posting 8933.33% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 8933.33%, up 822551.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 15754.2% (down 1449501.0% YoY), and the FY2025 annual result was 18933.65%, down 1768327.0% from the prior year.
  • Operating Margin came in at 8933.33% for Q1 2026 at CRISPR Therapeutics AG, up from 17912.5% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 34.58% in Q4 2023 to a low of 2192350.0% in Q4 2022.
  • The 5-year median for Operating Margin is 18103.26% (2024), against an average of 167590.53%.
  • Across the five-year window, Operating Margin slumped 219122047 bps in 2022 and jumped 219238458 bps in 2023, its largest moves.
  • CRISPR Therapeutics AG's Operating Margin stood at 2192350.0% in 2022, then surged by 100 bps to 34.58% in 2023, then slumped by 623 bps to 180.96% in 2024, then tumbled by 9798 bps to 17912.5% in 2025, then jumped by 50 bps to 8933.33% in 2026.
  • The last three Operating Margin figures came in at 8933.33% (Q1 2026), 17912.5% (Q4 2025), and 14854.78% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 CRISPR Therapeutics AG 5.21 Bn 2.76 Bn - -8,933.33%

Historic Data

Download Data
DateValue
Mar 31, 2026 -8,933.33%
Dec 31, 2025 -17,912.50%
Sep 30, 2025 -14,854.78%
Jun 30, 2025 -25,708.97%
Mar 31, 2025 -17,158.84%
Dec 31, 2024 -180.96%
Sep 30, 2024 -18,294.02%
Jun 30, 2024 -29,257.25%
Mar 31, 2024 -27,894.25%
Dec 31, 2023 34.58%
Jun 30, 2023 -136.03%
Mar 31, 2023 -64.49%
Dec 31, 2022 -2,192,350.00%
Sep 30, 2022 -194,029.79%
Jun 30, 2022 -115,987.34%
Mar 31, 2022 -18,720.43%
Dec 31, 2021 -1,129.53%
Sep 30, 2021 -15,637.01%
Jun 30, 2021 84.67%
Mar 31, 2021 -21,251.02%