Crinetics Pharmaceuticals (CRNX) Operating Margin (2017 - 2026)
Crinetics Pharmaceuticals (CRNX) recorded quarterly Operating Margin of 1307.79% in Q1 2026, up 39.72% quarter-over-quarter from 2169.55% in Q4 2025, and up 2955232.0% on a YoY basis from N/an in Q1 2025.
Crinetics Pharmaceuticals (CRNX) Operating Margin (2017 - 2026) Analysis & Trends
Crinetics Pharmaceuticals' Operating Margin history runs 10 years deep, the most recent figure standing at 1307.79% for Q1 2026.
- In Q1 2026, Operating Margin rose 2955232.0% year-over-year to 1307.79%; the TTM figure through Mar 2026 stood at 3020.32% (up 4654941.0% YoY), while the FY2025 annual figure was 6714.77%, up 2589870.0% from the prior year.
- Operating Margin was 1307.79% for Q1 2026 at Crinetics Pharmaceuticals, up from 2169.55% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 1080.39% in Q1 2022 to a low of 99710.49% in Q3 2025.
- Historically, Operating Margin has averaged 16434.89% across 5 years, with a median of 9646.51% in 2022.
- The sharpest annual moves came in 2025 and 2026: Operating Margin sank 1937120 bps in 2025, then jumped 2955232 bps in 2026.
- A 5-year view of Operating Margin shows it stood at 6707.48% in 2022, then plunged by 154 bps to 17045.38% in 2023, then slipped by 22 bps to 20747.62% in 2024, then surged by 90 bps to 2169.55% in 2025, then surged by 40 bps to 1307.79% in 2026.
- The last three Operating Margin figures came in at 1307.79% (Q1 2026), 2169.55% (Q4 2025), and 99710.49% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | - |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -6.43% |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | - |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | - |
| 10 | Crinetics Pharmaceuticals | 3.58 Bn | 3.58 Bn | 10.53 Mn | -1,307.79% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,307.79% |
| Dec 31, 2025 | -2,169.55% |
| Sep 30, 2025 | -99,710.49% |
| Jun 30, 2025 | -12,522.99% |
| Mar 31, 2025 | -30,860.11% |
| Jun 30, 2024 | -20,747.62% |
| Mar 31, 2024 | -11,488.91% |
| Sep 30, 2023 | -17,045.38% |
| Jun 30, 2023 | -5,363.87% |
| Mar 31, 2023 | -1,790.89% |
| Dec 31, 2022 | -6,707.48% |
| Sep 30, 2022 | -9,487.77% |
| Jun 30, 2022 | -9,805.24% |
| Mar 31, 2022 | -1,080.39% |
| Dec 31, 2021 | -2,865.31% |
| Dec 31, 2020 | 30,691.55% |
| Mar 31, 2020 | -25,045.07% |
| Dec 31, 2019 | -4,739.56% |
| Sep 30, 2019 | -3,015.64% |
| Mar 31, 2019 | -2,736.78% |