Crinetics Pharmaceuticals, Inc. (CRNX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

94,215,000Shares Outstanding

106,955,026Shares held by institutions

$4,002,257,073Value of institutional holdings

113.52%Institutional ownership %

-0.99%Shares Changed QoQ

232No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) showed up in the 13F filings of 232 institutional investors as of December 2025.

These investors held 112.9% of outstanding shares in December 2025, down from 122.4% in September 2025.
They decreased total shares held in Crinetics Pharmaceuticals by -1.16% from last quarter, and the number of investors in CRNX decreased 5.31% annually.
Among the 232 funds, 138 bought more Crinetics Pharmaceuticals shares, 74 sold down, and 20 held their ground.
In total, institutional investors held 106.38Mn shares in Crinetics Pharmaceuticals as of December 2025, down by 1.25Mn shares quarter on quarter, and up 5.49Mn shares year over year.
Pictet Asset Management Holding SA is the top holder of Crinetics Pharmaceuticals as of December 31, 2025, with 1.88Mn shares representing 2.0% of outstanding stock.
The most significant purchases of CRNX for the quarter ending December 2025 came from BRAUN STACEY ASSOCIATES INC (324.81K), Pictet Asset Management Holding SA (323.98K), MOODY ALDRICH PARTNERS LLC (73.02K), SANDERS MORRIS HARRIS LLC (21.1K), OPPENHEIMER ASSET MANAGEMENT INC. (3.94K).
Top sellers of CRNX stock for the quarter ending December 2025 included SG Americas Securities, LLC (12.22K), STRS OHIO (1.8K), PSP Research LLC (316), Farther Finance Advisors, LLC (305), GAMMA Investing LLC (58).
Per Business Quant data, the top 10 holders of Crinetics Pharmaceuticals for the quarter ending December 2025 are Pictet Asset Management Holding SA (1.88Mn), BRAUN STACEY ASSOCIATES INC (324.81K), MOODY ALDRICH PARTNERS LLC (183.44K), Lewis Asset Management, LLC (26.16K), OPPENHEIMER ASSET MANAGEMENT INC. (21.73K), SANDERS MORRIS HARRIS LLC (21.1K), PSP Research LLC (11.0K), SG Americas Securities, LLC (9.57K), PARK AVENUE SECURITIES LLC (7.05K), STRS OHIO (3.5K).

232 Institutional Holders

106,955,026 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	14,293,775	106,277	0.75%	$665,375,245.00
VANGUARD GROUP INC	31 Dec, 2025	9,135,504	-34,625	-0.38%	$425,257,712.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	8,037,889	-344,102	-4.11%	$374,163,733.00
BlackRock, Inc.	31 Dec, 2025	7,988,548	401,951	5.30%	$371,866,926.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,933,098	-4,607,098	-39.92%	$322,735,712.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,387,740	-93,873	-1.45%	$297,349,297.00
Janus Henderson Group Plc	31 Dec, 2025	4,440,691	581,900	15.08%	$206,603,847.00
EcoR1 Capital, LLC	31 Dec, 2025	4,288,120	0	0.00%	$199,611,986.00
Point72 Asset Management, L.P.	31 Dec, 2025	2,337,034	333,701	16.66%	$108,788,933.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,242,631	-36,199	-1.59%	$104,411,409.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	2,210,774	-340,000	-13.33%	$102,911,530.00
State Street Corp	31 Dec, 2025	2,161,378	-46,329	-2.10%	$100,612,146.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	1,648,869	1,368,869	488.88%	$76,754,852.00
Novo Holdings A/S	31 Dec, 2025	1,625,000	0	0.00%	$75,643,750.00
Pictet Asset Management Holding SA	31 Dec, 2025	1,560,300	95,038	6.49%	$72,631,965.00
Siren, L.L.C.	31 Dec, 2025	1,507,636	-180,975	-10.72%	$70,180,456.00
GW&K Investment Management, LLC	31 Dec, 2025	1,476,325	625,779	73.57%	$68,723.00
RTW INVESTMENTS, LP	31 Dec, 2025	1,351,326	478,939	54.90%	$62,904,225.00
BNP Paribas Asset Management Holding S.A.	31 Dec, 2025	1,327,382	493,351	59.15%	$61,789.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	1,281,601	-763,133	-37.32%	$59,658,525.00

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