Crinetics Pharmaceuticals, Inc. (CRNX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

93,605,531Shares Outstanding

6,307,708Shares held by institutions

$275,520,685Value of institutional holdings

113.20%Institutional ownership %

5.71%Shares Changed QoQ

231No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) includes 231 filers as of the latest reporting cycle ending December 2025.

Crinetics Pharmaceuticals saw its institutional ownership percentage fell to 113.2% in December 2025 from 115.4% in September 2025.
The company experienced a 5.71% quarterly change in institutional shares held, alongside a decrease of 5.71% in total owners annually.
A review of institutional activity for Crinetics Pharmaceuticals shows 139 of 231 filers increasing their positions, while 71 reduced their stake, and 21 remained unchanged.
This class of investors increased its holdings in Crinetics Pharmaceuticals to 105.96Mn shares for the 13F-cycle ending December 2025, up by 5.72Mn shares quarter on quarter, and up 6.54Mn shares year over year.
As of December 31, 2025, FMR LLC held Crinetics Pharmaceuticals's largest shareholding position with over 14.29Mn shares, representing 15.27% of total outstanding shares.
Among the most significant buyers of Crinetics Pharmaceuticals during December 2025 were BAKER BROS. ADVISORS LP (1.37Mn), FARALLON CAPITAL MANAGEMENT LLC (1.16Mn), GW&K Investment Management, LLC (625.78K), JANUS HENDERSON GROUP PLC (581.90K), UBS Group AG (500.47K).
Leading sellers of Crinetics Pharmaceuticals stock in December 2025 included JENNISON ASSOCIATES LLC (763.13K), CITADEL ADVISORS LLC (629.79K), WELLINGTON MANAGEMENT GROUP LLP (344.10K), Paradigm Biocapital Advisors LP (340.00K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (223.99K).
The top 10 institutional holders of Crinetics Pharmaceuticals for the quarter ending December 2025 included FMR LLC (14.29Mn), VANGUARD GROUP INC (9.14Mn), WELLINGTON MANAGEMENT GROUP LLP (8.04Mn), BlackRock, Inc. (7.99Mn), FARALLON CAPITAL MANAGEMENT LLC (6.93Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (6.39Mn), JANUS HENDERSON GROUP PLC (4.44Mn), EcoR1 Capital, LLC (4.29Mn), Point72 Asset Management, L.P. (2.34Mn), GEODE CAPITAL MANAGEMENT, LLC (2.24Mn).

231 Institutional Holders

6,307,708 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	14,293,775	106,277	0.75%	$665,375,245.00
VANGUARD GROUP INC	31 Dec, 2025	9,135,504	-34,625	-0.38%	$425,257,712.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	8,037,889	-344,102	-4.11%	$374,163,733.00
BlackRock, Inc.	31 Dec, 2025	7,988,548	401,951	5.30%	$371,866,926.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,933,098	1,163,000	20.16%	$322,735,712.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	6,387,740	-93,873	-1.45%	$297,349,297.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	4,440,691	581,900	15.08%	$206,603,847.00
EcoR1 Capital, LLC	31 Dec, 2025	4,288,120	0	0.00%	$199,611,986.00
Point72 Asset Management, L.P.	31 Dec, 2025	2,337,034	333,701	16.66%	$108,788,933.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,242,631	-36,199	-1.59%	$104,411,409.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	2,210,774	-340,000	-13.33%	$102,911,530.00
STATE STREET CORP	31 Dec, 2025	2,161,378	-46,329	-2.10%	$100,612,146.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	1,648,869	1,368,869	488.88%	$76,754,852.00
Novo Holdings A/S	31 Dec, 2025	1,625,000	0	0.00%	$75,643,750.00
Pictet Asset Management Holding SA	31 Dec, 2025	1,560,300	95,038	6.49%	$72,631,965.00
Siren, L.L.C.	31 Dec, 2025	1,507,636	-180,975	-10.72%	$70,180,456.00
GW&K Investment Management, LLC	31 Dec, 2025	1,476,325	625,779	73.57%	$68,723.00
RTW INVESTMENTS, LP	31 Dec, 2025	1,351,326	478,939	54.90%	$62,904,225.00
BNP Paribas Asset Management Holding S.A.	31 Dec, 2025	1,327,382	493,351	59.15%	$61,789.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	1,281,601	-763,133	-37.32%	$59,658,525.00

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