Caribou Biosciences (CRBU) Operating Margin (2020 - 2026)
Caribou Biosciences (CRBU) recorded Operating Margin of -1690.39% in Q2 2026, up 93.56 percentage points from -1783.95% a year earlier but down 594.02 percentage points from the prior quarter.
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Analysis
Caribou Biosciences (CRBU) Operating Margin (2020 - 2026) Analysis & Trends
On a TTM basis, Caribou Biosciences' Operating Margin came in at -1090.90% as of Jun 30, 2026, up 746.66 percentage points year-over-year; for FY2025, it came in at -1329.37%, up 337.79 percentage points from FY2024.
- Annual Operating Margin has a five-year change of -1037.12 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -1667.16% in FY2024 (-1330.53 pp), -336.63% in FY2023 (+431.54 pp), -768.17% in FY2022 (-70.33 pp) and -697.84% in FY2021 (-405.60 pp).
- Quarterly Operating Margin has ranged from -1893.87% in Q1 2024 to -61.84% in Q3 2023 over the past five years.
- On a year-over-year basis, Operating Margin has increased for four consecutive quarters, with an average year-over-year change of -72.81 percentage points over the last eight quarters.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 1149.72 percentage points in Q4 2025, against a drop of 1827.39 percentage points in Q3 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -1096.37% (Q1 2026), -721.97% (Q4 2025) and -1337.58% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Caribou Biosciences | 130.37 Mn | -386.16 Mn | - | -1,690.39% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,690.39% |
| Mar 31, 2026 | -1,096.37% |
| Dec 31, 2025 | -721.97% |
| Sep 30, 2025 | -1,337.58% |
| Jun 30, 2025 | -1,783.95% |
| Mar 31, 2025 | -1,823.76% |
| Dec 31, 2024 | -1,871.69% |
| Sep 30, 2024 | -1,889.23% |
| Jun 30, 2024 | -1,255.80% |
| Mar 31, 2024 | -1,893.87% |
| Dec 31, 2023 | -1,052.33% |
| Sep 30, 2023 | -61.84% |
| Jun 30, 2023 | -875.31% |
| Mar 31, 2023 | -888.52% |
| Dec 31, 2022 | -828.22% |
| Sep 30, 2022 | -803.42% |
| Jun 30, 2022 | -678.22% |
| Mar 31, 2022 | -782.77% |
| Dec 31, 2021 | -797.38% |
| Sep 30, 2021 | -468.09% |
API Access
Caribou Biosciences Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CRBU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();