Coya Therapeutics (COYA) Operating Margin (2023 - 2026)
Coya Therapeutics (COYA) reported Operating Margin of 3042.13% for Q1 2026, down 6524.0% on a YoY basis from 47.36% in Q1 2025, and down 1897.52% sequentially from 152.3% in Q4 2025.
Coya Therapeutics (COYA) Operating Margin (2023 - 2026) Analysis & Trends
Coya Therapeutics (COYA) has 4 years of Operating Margin data on file, last reported at 3042.13% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin fell 6524.0% year-over-year to 3042.13%; the trailing twelve-month figure through Mar 2026 stood at 283.64% (up 24398.0% YoY), and the FY2025 full-year result was 283.87%, up 20149.0% from the prior year.
- Operating Margin fell to 3042.13% in Q1 2026, from 152.3% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 30.24% in Q4 2023 to a low of 209031.51% in Q4 2024.
- A 4-year average of 24842.07% and a median of 2976.89% in 2025 frame the typical range for Operating Margin.
- Across the five-year window, Operating Margin sank 20906175 bps in 2024 and soared 20887921 bps in 2025, its largest moves.
- Tracing COYA's Operating Margin over 4 years: stood at 30.24% in 2023, then tumbled by 691308 bps to 209031.51% in 2024, then jumped by 100 bps to 152.3% in 2025, then tumbled by 1898 bps to 3042.13% in 2026.
- Business Quant data shows COYA's Operating Margin at 3042.13% in Q1 2026, 152.3% in Q4 2025, and 68.26% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | - |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | 16.51% |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | - |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | - |
| 10 | Coya Therapeutics | 97.14 Mn | 46.42 Mn | - | -3,042.13% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -3,042.13% |
| Dec 31, 2025 | -152.30% |
| Sep 30, 2025 | -68.26% |
| Jun 30, 2025 | -3,920.47% |
| Mar 31, 2025 | -2,976.89% |
| Dec 31, 2024 | -209,031.51% |
| Jun 30, 2024 | -94.48% |
| Mar 31, 2024 | -4,322.84% |
| Dec 31, 2023 | 30.24% |