Cellectis (CLLS) Operating Margin (2015 - 2026)
Cellectis' Operating Margin was -449.82% in Q2 2026, down 392.50 percentage points from -57.32% a year earlier and down 14.18 percentage points from the prior quarter.
Cellectis (CLLS) Operating Margin (2015 - 2026) Analysis & Trends
On a trailing twelve-month basis, Cellectis' Operating Margin was -98.48% through Jun 30, 2026, down 18.17 percentage points year-over-year; for FY2025, it was -45.34%, up 98.15 percentage points from FY2024.
- Operating Margin shows a five-year change of +143.05 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -143.49% in FY2024 (+12744.20 pp), -12887.68% in FY2023 (-12419.97 pp), -467.72% in FY2022 (-126.72 pp) and -340.99% in FY2021 (-152.60 pp).
- The Q2 2026 figure marks the lowest quarterly Operating Margin since Q1 2024.
- Compared with a year earlier, Operating Margin has declined for three straight quarters, with an average year-over-year change of +2933.00 percentage points over the last eight quarters.
- The best year-over-year quarter for Operating Margin over five years was Q1 2024 (a gain of 16395.39 percentage points); the worst was Q3 2022 (a drop of 15120.56 percentage points).
- Per Business Quant data, CLLS's Operating Margin in the three quarters before Q2 2026 was -435.64% (Q1 2026), -136.46% (Q4 2025) and 22.86% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Cellectis | 111.38 Mn | -642.02 Mn | - | -449.82% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -449.82% |
| Mar 31, 2026 | -435.64% |
| Dec 31, 2025 | -136.46% |
| Sep 30, 2025 | 22.86% |
| Jun 30, 2025 | -57.32% |
| Mar 31, 2025 | -133.07% |
| Dec 31, 2024 | -83.99% |
| Sep 30, 2024 | -66.48% |
| Jun 30, 2024 | -213.51% |
| Mar 31, 2024 | -461.44% |
| Dec 31, 2023 | -10,451.94% |
| Sep 30, 2023 | -13,336.13% |
| Jun 30, 2023 | -13,270.22% |
| Mar 31, 2023 | -16,856.83% |
| Dec 31, 2022 | -35.32% |
| Sep 30, 2022 | -15,630.29% |
| Jun 30, 2022 | -2,089.75% |
| Mar 31, 2022 | -1,755.44% |
| Dec 31, 2021 | -239.33% |
| Sep 30, 2021 | -509.72% |
Cellectis Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CLLS&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CLLS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CLLS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();