Bicycle Therapeutics (BCYC) Operating Margin (2018 - 2026)
Bicycle Therapeutics' Operating Margin was -8673.93% in Q2 2026, down 5708.10 percentage points from -2965.82% a year earlier and down 1291.51 percentage points from the prior quarter.
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Analysis
Bicycle Therapeutics (BCYC) Operating Margin (2018 - 2026) Analysis & Trends
On a trailing twelve-month basis, Bicycle Therapeutics' Operating Margin was -343.60% through Jun 30, 2026, up 1151.73 percentage points year-over-year; for FY2025, it was -340.38%, up 254.58 percentage points from FY2024.
- Operating Margin has now increased for three consecutive years, with a five-year change of +159.72 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -594.96% in FY2024 (+109.17 pp), -704.13% in FY2023 (+102.43 pp), -806.56% in FY2022 (-245.58 pp) and -560.98% in FY2021 (-60.89 pp).
- The Q2 2026 figure marks the lowest quarterly Operating Margin in data going back to Q2 2018.
- Compared with a year earlier, Operating Margin was higher in two of the last eight quarters, with an average year-over-year change of -1754.92 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q3 2025 (a gain of 1827.23 percentage points); the worst was Q1 2026 (a drop of 6678.75 percentage points).
- Per Business Quant data, BCYC's Operating Margin in the three quarters before Q2 2026 was -7382.41% (Q1 2026), -51.52% (Q4 2025) and -558.64% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Bicycle Therapeutics | 259.01 Mn | 259.01 Mn | - | -8,673.93% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -8,673.93% |
| Mar 31, 2026 | -7,382.41% |
| Dec 31, 2025 | -51.52% |
| Sep 30, 2025 | -558.64% |
| Jun 30, 2025 | -2,965.82% |
| Mar 31, 2025 | -703.66% |
| Dec 31, 2024 | -1,824.78% |
| Sep 30, 2024 | -2,385.87% |
| Jun 30, 2024 | -498.31% |
| Mar 31, 2024 | -162.40% |
| Dec 31, 2023 | -1,017.35% |
| Sep 30, 2023 | -949.12% |
| Jun 30, 2023 | -378.27% |
| Mar 31, 2023 | -853.82% |
| Dec 31, 2022 | -1,011.33% |
| Sep 30, 2022 | -978.91% |
| Jun 30, 2022 | -623.57% |
| Mar 31, 2022 | -709.40% |
| Dec 31, 2021 | -477.96% |
| Sep 30, 2021 | -329.89% |
API Access
Bicycle Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=BCYC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "BCYC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=BCYC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();