Biocryst Pharmaceuticals (BCRX) Operating Margin (2010 - 2026)

Biocryst Pharmaceuticals (BCRX) reported Operating Margin of 448.55% for Q1 2026, down 46314.0% on a YoY basis from N/an in Q1 2025, and down 101.22% quarter-over-quarter from 36777.54% in Q4 2025.

Biocryst Pharmaceuticals (BCRX) Operating Margin (2010 - 2026) Analysis & Trends

Biocryst Pharmaceuticals has reported Operating Margin for 17 years, with the latest figure at 448.55% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin fell 46314.0% year-over-year to 448.55%; the trailing twelve-month figure through Mar 2026 stood at 79.57% (down 8616.0% YoY), and the FY2025 full-year result was 38.98%, up 3954.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 448.55%, down from 36777.54% in the prior quarter.
  • The five-year high for Operating Margin was 36777.54% in Q4 2025, with the low at 448.55% in Q1 2026.
  • Historically, Operating Margin has averaged 2118.58% across 5 years, with a median of 15.62% in 2024.
  • Annual changes were most pronounced in 2025 — Operating Margin soared 3678097 bps — and 2026, when it sank 46314 bps.
  • Biocryst Pharmaceuticals' Operating Margin stood at 58.22% in 2022, then climbed by 22 bps to 45.68% in 2023, then soared by 92 bps to 3.43% in 2024, then jumped by 1073192 bps to 36777.54% in 2025, then tumbled by 101 bps to 448.55% in 2026.
  • The last three Operating Margin figures came in at 448.55% (Q1 2026), 36777.54% (Q4 2025), and 18.56% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Teva Pharmaceutical Industries 38.34 Bn 34.60 Bn 1.97 Bn 16.37%
2 Zoetis 33.27 Bn 31.33 Bn 1.62 Bn 36.83%
3 United Therapeutics 23.75 Bn 21.60 Bn 648.10 Mn 41.69%
4 Aurora Cannabis 17.11 Bn 17.03 Bn 33.43 Mn 20.77%
5 Neurocrine Biosciences 16.37 Bn 15.05 Bn 800.70 Mn 23.74%
6 Elanco Animal Health 11.78 Bn 11.35 Bn 785.00 Mn 22.39%
7 Alkermes 7.05 Bn 6.54 Bn -116.06 Mn -122.23%
8 Lantheus Holdings 6.49 Bn 5.99 Bn 230.92 Mn 21.55%
9 Hims & Hers Health 6.19 Bn 5.44 Bn 396.79 Mn -12.88%
10 Biocryst Pharmaceuticals 2.04 Bn 1.81 Bn 151.04 Mn -448.55%

Historic Data

Download Data
DateValue
Mar 31, 2026 -448.55%
Dec 31, 2025 36,777.54%
Sep 30, 2025 18.56%
Jun 30, 2025 18.23%
Mar 31, 2025 14.59%
Dec 31, 2024 -3.43%
Sep 30, 2024 6.57%
Jun 30, 2024 8.01%
Mar 31, 2024 -15.62%
Dec 31, 2023 -45.68%
Sep 30, 2023 -13.74%
Jun 30, 2023 -25.10%
Mar 31, 2023 -41.31%
Dec 31, 2022 -58.22%
Sep 30, 2022 -23.01%
Jun 30, 2022 -52.98%
Mar 31, 2022 -100.07%
Dec 31, 2021 -110.64%
Sep 30, 2021 -108.76%
Jun 30, 2021 -59.21%