Avalo Therapeutics (AVTX) Operating Margin (2016 - 2025)
Avalo Therapeutics (AVTX) reported Operating Margin of -33461.02% for Q4 2025, down 26528.20 percentage points from -6932.81% a year earlier.
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Analysis
Avalo Therapeutics (AVTX) Operating Margin (2016 - 2025) Analysis & Trends
For FY2025, Avalo Therapeutics posted Operating Margin of -123601.69%, down 108066.09 percentage points from FY2024.
- Operating Margin has declined for three consecutive years, with a five-year change of -122514.32 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -15535.60% in FY2024 (-14114.03 pp), -1421.57% in FY2023 (-1214.16 pp), -207.41% in FY2022 (+1314.15 pp) and -1521.56% in FY2021 (-434.19 pp).
- The Q4 2025 figure ranks as the lowest quarterly Operating Margin in data going back to Q3 2016.
- The high point for year-over-year Operating Margin in five years was Q4 2022 (a gain of 7214.00 percentage points); the low point was Q4 2025 (a drop of 26528.20 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Avalo Therapeutics | 657.52 Mn | 657.52 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -33,461.02% |
| Dec 31, 2024 | -6,932.81% |
| Sep 30, 2024 | -5,165.06% |
| Dec 31, 2023 | -1,341.16% |
| Sep 30, 2023 | -1,588.98% |
| Jun 30, 2023 | -1,111.98% |
| Mar 31, 2023 | -1,850.95% |
| Dec 31, 2022 | -988.28% |
| Sep 30, 2022 | 27.39% |
| Jun 30, 2022 | -1,145.01% |
| Mar 31, 2022 | -1,777.75% |
| Dec 31, 2021 | -8,202.28% |
| Sep 30, 2021 | -1,219.48% |
| Jun 30, 2021 | -510.55% |
| Mar 31, 2021 | -6,465.12% |
| Dec 31, 2020 | -1,091.45% |
| Sep 30, 2020 | -1,195.05% |
| Jun 30, 2020 | -883.03% |
| Mar 31, 2020 | -1,140.63% |
| Dec 31, 2019 | -985.32% |
API Access
Avalo Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=AVTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "AVTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=AVTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();