Ascendis Pharma A (ASND) Operating Margin (2014 - 2026)

Ascendis Pharma A (ASND) reported Operating Margin of 10.06% for Q1 2026, up 11329.0% on a YoY basis from N/an in Q1 2025, and up 323.42% sequentially from 2.38% in Q4 2025.

Ascendis Pharma A (ASND) Operating Margin (2014 - 2026) Analysis & Trends

Ascendis Pharma A (ASND) has 13 years of Operating Margin data on file, last reported at 10.06% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin rose 11329.0% year-over-year to 10.06%; the trailing twelve-month figure through Mar 2026 stood at 0.54% (down 7576475.0% YoY), and the FY2025 full-year result was 18.92%, up 4978.0% from the prior year.
  • Operating Margin improved to 10.06% in Q1 2026, from 2.38% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 123555.16% in Q4 2024 to a low of 2303.46% in Q2 2022.
  • A 5-year average of 6827.24% and a median of 167.28% in 2024 frame the typical range for Operating Margin.
  • Across the five-year window, Operating Margin surged 12356726 bps in 2024 and slumped 12355279 bps in 2025, its largest moves.
  • Tracing ASND's Operating Margin over 5 years: stood at 643.75% in 2022, then soared by 98 bps to 12.09% in 2023, then surged by 1021723 bps to 123555.16% in 2024, then slumped by 100 bps to 2.38% in 2025, then surged by 323 bps to 10.06% in 2026.
  • Business Quant data shows ASND's Operating Margin at 10.06% in Q1 2026, 2.38% in Q4 2025, and 5.15% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 17.83%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 30.35%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Ascendis Pharma A 15.35 Bn 14.68 Bn 268.20 Mn 10.06%

Historic Data

Download Data
DateValue
Mar 31, 2026 10.06%
Dec 31, 2025 2.38%
Sep 30, 2025 5.15%
Jun 30, 2025 -33.50%
Mar 31, 2025 -103.23%
Dec 31, 2024 123,555.16%
Sep 30, 2024 -167.28%
Jun 30, 2024 -370.18%
Mar 31, 2024 -51.25%
Dec 31, 2023 -12.09%
Sep 30, 2023 -279.82%
Jun 30, 2023 -297.17%
Mar 31, 2023 -427.77%
Dec 31, 2022 -643.75%
Sep 30, 2022 -945.09%
Jun 30, 2022 -2,303.46%
Mar 31, 2022 -1,875.06%
Dec 31, 2021 -130.71%
Sep 30, 2021 -8,709.07%
Jun 30, 2021 -11,509.69%