Ascendis Pharma A (ASND) Operating Margin (2014 - 2026)
Ascendis Pharma A (ASND) reported Operating Margin of 64.98% for the quarter ended Jun 30, 2026, up 98.48 percentage points from -33.50% a year earlier and up 54.92 percentage points from the prior quarter.
Ascendis Pharma A (ASND) Operating Margin (2014 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Ascendis Pharma A's Operating Margin came in at 25.36%, up 76.89 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -18.92%, up 49.78 percentage points from the prior year.
- Operating Margin has increased for four consecutive years, with a five-year change of +4736.15 percentage points (years ended Dec 2020 to Dec 2025).
- By year, Operating Margin came in at -68.70% in the year ended Dec 31, 2024 (+102.10 pp), -170.79% in the year ended Dec 31, 2023 (+927.06 pp), -1097.85% in the year ended Dec 31, 2022 (+4710.74 pp) and -5808.59% in the year ended Dec 31, 2021 (-1053.52 pp).
- The figure for the quarter ended Jun 30, 2026 ranks as the highest quarterly Operating Margin in data going back to the quarter ended Mar 31, 2014.
- Year over year, Operating Margin has now increased in each of the last five quarters, with an average year-over-year change of +99.69 percentage points over the last eight quarters.
- The high point for year-over-year Operating Margin in five years was the quarter ended Mar 31, 2022 (a gain of 14834.06 percentage points); the low point was the quarter ended Sep 30, 2021 (a drop of 5849.99 percentage points).
- Per Business Quant data, the three quarters before the quarter ended Jun 30, 2026 came in at 10.06% (quarter ended Mar 31, 2026), 4.00% (quarter ended Dec 31, 2025) and 5.15% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Ascendis Pharma A | 14.26 Bn | 10.50 Bn | 362.22 Mn | 64.98% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 64.98% |
| Mar 31, 2026 | 10.06% |
| Dec 31, 2025 | 4.00% |
| Sep 30, 2025 | 5.15% |
| Jun 30, 2025 | -33.50% |
| Mar 31, 2025 | -103.23% |
| Dec 31, 2024 | 0.22% |
| Sep 30, 2024 | -167.28% |
| Jun 30, 2024 | -370.18% |
| Mar 31, 2024 | -51.25% |
| Dec 31, 2023 | -12.09% |
| Sep 30, 2023 | -279.82% |
| Jun 30, 2023 | -297.17% |
| Mar 31, 2023 | -427.77% |
| Dec 31, 2022 | -643.75% |
| Sep 30, 2022 | -945.09% |
| Jun 30, 2022 | -2,303.46% |
| Mar 31, 2022 | -1,875.06% |
| Dec 31, 2021 | -130.71% |
| Sep 30, 2021 | -8,709.07% |
Ascendis Pharma A Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ASND&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ASND", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ASND&period=max&api_key=YOUR_API_KEY");
const data = await res.json();