Ardelyx (ARDX) Operating Margin (2013 - 2026)
Ardelyx (ARDX) reported Operating Margin of 34.71% for Q1 2026, up 1433.0% on a YoY basis from 2.26% in Q1 2025, and down 952.4% quarter-over-quarter from 4.07% in Q4 2025.
Ardelyx (ARDX) Operating Margin (2013 - 2026) Analysis & Trends
Ardelyx has reported Operating Margin for 12 years, with the latest figure at 34.71% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin rose 1433.0% year-over-year to 34.71%; the trailing twelve-month figure through Mar 2026 stood at 11.67% (down 71.0% YoY), and the FY2025 full-year result was 10.06%, down 168.0% from the prior year.
- Operating Margin for Q1 2026 stood at 34.71%, down from 4.07% in the prior quarter.
- The five-year high for Operating Margin was 137.29% in Q3 2025, with the low at 5941.67% in Q1 2022.
- Historically, Operating Margin has averaged 457.82% across 5 years, with a median of 34.71% in 2026.
- Annual changes were most pronounced in 2022 — Operating Margin tumbled 545542 bps — and 2023, when it jumped 571241 bps.
- Ardelyx's Operating Margin stood at 27.49% in 2022, then plunged by 396 bps to 81.44% in 2023, then jumped by 109 bps to 7.0% in 2024, then slumped by 42 bps to 4.07% in 2025, then plunged by 952 bps to 34.71% in 2026.
- The last three Operating Margin figures came in at 34.71% (Q1 2026), 4.07% (Q4 2025), and 137.29% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Ardelyx | 1.49 Bn | 1.25 Bn | 89.66 Mn | -34.71% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -34.71% |
| Dec 31, 2025 | 4.07% |
| Sep 30, 2025 | 137.29% |
| Jun 30, 2025 | -14.74% |
| Mar 31, 2025 | -49.04% |
| Dec 31, 2024 | 7.00% |
| Sep 30, 2024 | 2.27% |
| Jun 30, 2024 | -18.61% |
| Mar 31, 2024 | -53.62% |
| Dec 31, 2023 | -81.44% |
| Sep 30, 2023 | 13.12% |
| Jun 30, 2023 | -74.44% |
| Mar 31, 2023 | -229.25% |
| Dec 31, 2022 | 27.49% |
| Sep 30, 2022 | -438.83% |
| Jun 30, 2022 | -1,037.81% |
| Mar 31, 2022 | -5,941.67% |
| Dec 31, 2021 | -3,427.89% |
| Sep 30, 2021 | -3,600.68% |
| Jun 30, 2021 | -3,414.47% |