Altimmune (ALT) Operating Margin (2010 - 2025)
Altimmune's Operating Margin was -111126.92% in Q4 2025, up 386193.08 percentage points from -497320.00% a year earlier and up 306053.08 percentage points from the prior quarter.
Powered by 
Analysis
Altimmune (ALT) Operating Margin (2010 - 2025) Analysis & Trends
For FY2025, Operating Margin at Altimmune came in at -230460.98%, up 285399.02 percentage points from FY2024.
- Operating Margin shows a five-year change of -229791.48 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -515860.00% in FY2024 (-493341.46 pp), -22518.54% in FY2023 (+106510.87 pp), -129029.41% in FY2022 (-126831.82 pp) and -2197.60% in FY2021 (-1528.10 pp).
- The Q4 2025 figure marks the highest quarterly Operating Margin since Q4 2023.
- Compared with a year earlier, Operating Margin has increased for four straight quarters, with an average year-over-year change of -115277.06 percentage points over the last eight quarters.
- The best year-over-year quarter for Operating Margin over five years was Q3 2023 (a gain of 1231373.48 percentage points); the worst was Q3 2022 (a drop of 1216584.81 percentage points).
- Per Business Quant data, ALT's Operating Margin in the three quarters before Q4 2025 was -417180.00% (Q3 2025), -458440.00% (Q2 2025) and -436300.00% (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Altimmune | 577.59 Mn | 577.59 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -111,126.92% |
| Sep 30, 2025 | -417,180.00% |
| Jun 30, 2025 | -458,440.00% |
| Mar 31, 2025 | -436,300.00% |
| Dec 31, 2024 | -497,320.00% |
| Sep 30, 2024 | -495,340.00% |
| Jun 30, 2024 | -534,900.00% |
| Mar 31, 2024 | -535,880.00% |
| Dec 31, 2023 | -90,872.97% |
| Sep 30, 2023 | -6,226.52% |
| Jun 30, 2023 | -300,116.67% |
| Mar 31, 2023 | -103,614.29% |
| Dec 31, 2022 | -88,823.08% |
| Sep 30, 2022 | -1,237,600.00% |
| Jun 30, 2022 | -254,937.50% |
| Mar 31, 2022 | -60,934.38% |
| Dec 31, 2021 | -731.92% |
| Sep 30, 2021 | -21,015.19% |
| Jun 30, 2021 | -18,148.91% |
| Mar 31, 2021 | -1,773.39% |
API Access
Altimmune Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ALT&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ALT", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ALT&period=max&api_key=YOUR_API_KEY");
const data = await res.json();