Altimmune (ALT) Operating Margin (2010 - 2025)
Altimmune's (ALT) quarterly Operating Margin came in at 111126.92% in Q4 2025, up 38619308.0% year-on-year from N/an in Q4 2024, and up 73.36% on a QoQ basis from 417180.0% in Q3 2025.
Altimmune (ALT) Operating Margin (2010 - 2025) Analysis & Trends
Altimmune (ALT) has 16 years of Operating Margin data on file, last reported at 111126.92% in Q4 2025.
- On a quarterly basis, Operating Margin rose 38619308.0% year-over-year to 111126.92% in Q4 2025; TTM through Dec 2025 was 230460.98%, a 28539902.0% increase from a year earlier, with the FY2025 full-year figure at 230460.98%, up 28539902.0% from the prior year.
- Operating Margin for Q4 2025 stood at 111126.92%, up from 417180.0% in the prior quarter.
- Over the last five years, Operating Margin for ALT reached as high as 731.92% in Q4 2021 and fell as low as 1237600.0% in Q3 2022.
- Historically, Operating Margin has averaged 283564.09% across 5 years, with a median of 183032.21% in 2025.
- Across the five-year window, Operating Margin tumbled 121658481 bps in 2022 and jumped 123137348 bps in 2023, its largest moves.
- Year by year, Operating Margin stood at 731.92% in 2021, then tumbled by 12036 bps to 88823.08% in 2022, then declined by 2 bps to 90872.97% in 2023, then plunged by 447 bps to 497320.0% in 2024, then jumped by 78 bps to 111126.92% in 2025.
- Per Business Quant data, the three most recent Operating Margin figures were 111126.92% in Q4 2025, 417180.0% in Q3 2025, and 458440.0% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Altimmune | 7.96 Mn | 7.96 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -111,126.92% |
| Sep 30, 2025 | -417,180.00% |
| Jun 30, 2025 | -458,440.00% |
| Mar 31, 2025 | -436,300.00% |
| Dec 31, 2024 | -497,320.00% |
| Sep 30, 2024 | -495,340.00% |
| Jun 30, 2024 | -534,900.00% |
| Mar 31, 2024 | -535,880.00% |
| Dec 31, 2023 | -90,872.97% |
| Sep 30, 2023 | -6,226.52% |
| Jun 30, 2023 | -300,116.67% |
| Mar 31, 2023 | -103,614.29% |
| Dec 31, 2022 | -88,823.08% |
| Sep 30, 2022 | -1,237,600.00% |
| Jun 30, 2022 | -254,937.50% |
| Mar 31, 2022 | -60,934.38% |
| Dec 31, 2021 | -731.92% |
| Sep 30, 2021 | -21,015.19% |
| Jun 30, 2021 | -18,148.91% |
| Mar 31, 2021 | -1,773.39% |