Agenus (AGEN) Operating Margin (2010 - 2026)
Agenus' (AGEN) quarterly Operating Margin came in at 44.62% in Q1 2026, up 9993.0% year-on-year from N/an in Q1 2025, and up 6.01% quarter-over-quarter from 42.09% in Q4 2025.
Agenus (AGEN) Operating Margin (2010 - 2026) Analysis & Trends
Agenus' Operating Margin history runs 17 years deep, the most recent figure standing at 44.62% for Q1 2026.
- On a quarterly basis, Operating Margin rose 9993.0% year-over-year to 44.62% in Q1 2026; TTM through Mar 2026 was 6.62%, a 10800.0% increase from a year earlier, with the FY2025 full-year figure at 17.66%, up 9878.0% from the prior year.
- Operating Margin advanced to 44.62% in Q1 2026 per AGEN's latest filing, from 42.09% in the prior quarter.
- Across five years, Operating Margin topped out at 130.27% in Q4 2022 and bottomed at 237.28% in Q1 2023.
- The 5-year median for Operating Margin is 117.41% (2024), against an average of 92.22%.
- Biggest YoY gain for Operating Margin was 40581 bps in 2022; the steepest drop was 25702 bps in 2022.
- Year by year, Operating Margin stood at 130.27% in 2022, then tumbled by 104 bps to 5.01% in 2023, then slumped by 1825 bps to 96.49% in 2024, then surged by 144 bps to 42.09% in 2025, then advanced by 6 bps to 44.62% in 2026.
- Per Business Quant, the three latest AGEN Operating Margin figures stand at 44.62% (Q1 2026), 42.09% (Q4 2025), and 15.03% (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Agenus | 184.05 Mn | 177.29 Mn | 33.74 Mn | 44.62% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 44.62% |
| Dec 31, 2025 | 42.09% |
| Sep 30, 2025 | -15.03% |
| Jun 30, 2025 | -65.05% |
| Mar 31, 2025 | -55.31% |
| Dec 31, 2024 | -96.49% |
| Sep 30, 2024 | -125.45% |
| Jun 30, 2024 | -128.43% |
| Mar 31, 2024 | -117.41% |
| Dec 31, 2023 | -5.01% |
| Sep 30, 2023 | -190.59% |
| Jun 30, 2023 | -216.11% |
| Mar 31, 2023 | -237.28% |
| Dec 31, 2022 | 130.27% |
| Sep 30, 2022 | -182.88% |
| Jun 30, 2022 | -212.96% |
| Mar 31, 2022 | -136.70% |
| Dec 31, 2021 | -266.66% |
| Sep 30, 2021 | 74.14% |
| Jun 30, 2021 | -618.78% |