Agenus (AGEN) Operating Margin (2010 - 2026)
Agenus (AGEN) posted quarterly Operating Margin of 44.62% for Q1 2026, up 9993.0% year-over-year from N/an in Q1 2025, and up 6.01% quarter-over-quarter from 42.09% in Q4 2025.
Analysis
Agenus (AGEN) Operating Margin (2010 - 2026) Analysis & Trends
Agenus' Operating Margin history runs 17 years deep, the most recent figure standing at 44.62% for Q1 2026.
- In Q1 2026, Operating Margin rose 9993.0% year-over-year to 44.62%; the TTM figure through Mar 2026 stood at 6.62% (up 10800.0% YoY), while the FY2025 annual figure was 17.66%, up 9878.0% from the prior year.
- Operating Margin for Q1 2026 stood at 44.62%, up from 42.09% in the prior quarter.
- The five-year high for Operating Margin was 130.27% in Q4 2022, with the low at 237.28% in Q1 2023.
- The 5-year median for Operating Margin is 117.41% (2024), against an average of 92.22%.
- Peak annual rise in Operating Margin reached 40581 bps in 2022, while the deepest fall reached 25702 bps in 2022.
- Agenus' Operating Margin stood at 130.27% in 2022, then plunged by 104 bps to 5.01% in 2023, then tumbled by 1825 bps to 96.49% in 2024, then jumped by 144 bps to 42.09% in 2025, then gained by 6 bps to 44.62% in 2026.
- Business Quant data shows AGEN's Operating Margin at 44.62% in Q1 2026, 42.09% in Q4 2025, and 15.03% in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.27 Bn | 131.42 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.55 Bn | 77.56 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 63.45 Bn | 58.27 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 57.73 Bn | 52.59 Bn | 52.00 Mn | -562.07% |
| 5 | Revolution Medicines | 44.08 Bn | 44.08 Bn | - | - |
| 6 | BeOne Medicines | 39.95 Bn | 34.85 Bn | 1.53 Bn | 19.06% |
| 7 | Alnylam Pharmaceuticals | 35.14 Bn | 31.84 Bn | 992.69 Mn | 17.93% |
| 8 | Royalty Pharma | 28.44 Bn | 27.60 Bn | - | 19.75% |
| 9 | Insmed | 27.32 Bn | 26.16 Bn | 358.27 Mn | -0.36% |
| 10 | Agenus | 343.11 Mn | 343.11 Mn | 34.52 Mn | 32.72% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 32.72% |
| Mar 31, 2026 | 44.62% |
| Dec 31, 2025 | 42.09% |
| Sep 30, 2025 | -15.03% |
| Jun 30, 2025 | -65.05% |
| Mar 31, 2025 | -55.31% |
| Dec 31, 2024 | -96.49% |
| Sep 30, 2024 | -125.45% |
| Jun 30, 2024 | -128.43% |
| Mar 31, 2024 | -117.41% |
| Dec 31, 2023 | -5.01% |
| Sep 30, 2023 | -190.59% |
| Jun 30, 2023 | -216.11% |
| Mar 31, 2023 | -237.28% |
| Dec 31, 2022 | -203.47% |
| Sep 30, 2022 | -182.88% |
| Jun 30, 2022 | -212.96% |
| Mar 31, 2022 | -136.70% |
| Dec 31, 2021 | -266.66% |
| Sep 30, 2021 | 74.14% |