Adma Biologics (ADMA) Operating Margin (2011 - 2025)
Adma Biologics (ADMA) reported Operating Margin of 45.09% for Q4 2025, up 1249.0% on a YoY basis from 3.34% in Q4 2024, and up 18.65% quarter-over-quarter from 38.01% in Q3 2025.
Adma Biologics (ADMA) Operating Margin (2011 - 2025) Analysis & Trends
Adma Biologics has reported Operating Margin for 13 years, with the latest figure at 45.09% in Q4 2025.
- For the quarter ending Q4 2025, Operating Margin rose 1249.0% year-over-year to 45.09%; the trailing twelve-month figure through Dec 2025 stood at 37.52% (up 493.0% YoY), and the FY2025 full-year result was 37.53%, up 493.0% from the prior year.
- Operating Margin for Q4 2025 stood at 45.09%, up from 38.01% in the prior quarter.
- The five-year high for Operating Margin was 45.09% in Q4 2025, with the low at 94.49% in Q1 2021.
- Historically, Operating Margin has averaged 3.56% across 5 years, with a median of 3.55% in 2023.
- Annual changes were most pronounced in 2021 — Operating Margin surged 13250 bps — and 2025, when it plunged 149 bps.
- Adma Biologics' Operating Margin stood at 23.98% in 2021, then soared by 49 bps to 12.12% in 2022, then surged by 259 bps to 19.26% in 2023, then soared by 69 bps to 32.6% in 2024, then soared by 38 bps to 45.09% in 2025.
- The last three Operating Margin figures came in at 45.09% (Q4 2025), 38.01% (Q3 2025), and 35.08% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Adma Biologics | 1.98 Bn | 1.89 Bn | 88.82 Mn | 45.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 45.09% |
| Sep 30, 2025 | 38.01% |
| Jun 30, 2025 | 35.08% |
| Mar 31, 2025 | 30.38% |
| Dec 31, 2024 | 32.60% |
| Sep 30, 2024 | 33.08% |
| Jun 30, 2024 | 36.57% |
| Mar 31, 2024 | 26.65% |
| Dec 31, 2023 | 19.26% |
| Sep 30, 2023 | 7.90% |
| Jun 30, 2023 | -0.79% |
| Mar 31, 2023 | -1.43% |
| Dec 31, 2022 | -12.12% |
| Sep 30, 2022 | -22.67% |
| Jun 30, 2022 | -12.23% |
| Mar 31, 2022 | -50.91% |
| Dec 31, 2021 | -23.98% |
| Sep 30, 2021 | -69.81% |
| Jun 30, 2021 | -87.38% |
| Mar 31, 2021 | -94.49% |