Adma Biologics (ADMA) Operating Margin (2011 - 2025)

Adma Biologics (ADMA) reported Operating Margin of 45.09% for Q4 2025, up 1249.0% on a YoY basis from 3.34% in Q4 2024, and up 18.65% quarter-over-quarter from 38.01% in Q3 2025.

Adma Biologics (ADMA) Operating Margin (2011 - 2025) Analysis & Trends

Adma Biologics has reported Operating Margin for 13 years, with the latest figure at 45.09% in Q4 2025.

  • For the quarter ending Q4 2025, Operating Margin rose 1249.0% year-over-year to 45.09%; the trailing twelve-month figure through Dec 2025 stood at 37.52% (up 493.0% YoY), and the FY2025 full-year result was 37.53%, up 493.0% from the prior year.
  • Operating Margin for Q4 2025 stood at 45.09%, up from 38.01% in the prior quarter.
  • The five-year high for Operating Margin was 45.09% in Q4 2025, with the low at 94.49% in Q1 2021.
  • Historically, Operating Margin has averaged 3.56% across 5 years, with a median of 3.55% in 2023.
  • Annual changes were most pronounced in 2021 — Operating Margin surged 13250 bps — and 2025, when it plunged 149 bps.
  • Adma Biologics' Operating Margin stood at 23.98% in 2021, then soared by 49 bps to 12.12% in 2022, then surged by 259 bps to 19.26% in 2023, then soared by 69 bps to 32.6% in 2024, then soared by 38 bps to 45.09% in 2025.
  • The last three Operating Margin figures came in at 45.09% (Q4 2025), 38.01% (Q3 2025), and 35.08% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Adma Biologics 1.98 Bn 1.89 Bn 88.82 Mn 45.09%

Historic Data

Download Data
DateValue
Dec 31, 2025 45.09%
Sep 30, 2025 38.01%
Jun 30, 2025 35.08%
Mar 31, 2025 30.38%
Dec 31, 2024 32.60%
Sep 30, 2024 33.08%
Jun 30, 2024 36.57%
Mar 31, 2024 26.65%
Dec 31, 2023 19.26%
Sep 30, 2023 7.90%
Jun 30, 2023 -0.79%
Mar 31, 2023 -1.43%
Dec 31, 2022 -12.12%
Sep 30, 2022 -22.67%
Jun 30, 2022 -12.23%
Mar 31, 2022 -50.91%
Dec 31, 2021 -23.98%
Sep 30, 2021 -69.81%
Jun 30, 2021 -87.38%
Mar 31, 2021 -94.49%