AC Immune (ACIU) Operating Margin (2015 - 2026)
AC Immune (ACIU) reported Operating Margin of 7.89% for the quarter ended Jun 30, 2026, up 1492.43 percentage points from -1484.53% a year earlier and up 1329.43 percentage points from the prior quarter.
AC Immune (ACIU) Operating Margin (2015 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, AC Immune's Operating Margin came in at -251.02%, down 77.84 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -1940.05%, down 1748.25 percentage points from the prior year.
- Operating Margin has a five-year change of -1543.06 percentage points (years ended Dec 2020 to Dec 2025).
- By year, Operating Margin came in at -191.80% in the year ended Dec 31, 2024 (+170.50 pp), -362.30% in the year ended Dec 31, 2023 (+1438.13 pp) and -1800.43% in the year ended Dec 31, 2022.
- The figure for the quarter ended Jun 30, 2026 ranks as the highest quarterly Operating Margin since the quarter ended Sep 30, 2024.
- Year over year, Operating Margin gained in three of the last five quarters, with an average year-over-year change of -135.45 percentage points.
- Per Business Quant data, the three quarters before the quarter ended Jun 30, 2026 came in at -1321.54% (quarter ended Mar 31, 2026), -4258.58% (quarter ended Dec 31, 2025) and -1721.62% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | AC Immune | 265.55 Mn | 265.55 Mn | - | 7.89% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 7.89% |
| Mar 31, 2026 | -1,321.54% |
| Dec 31, 2025 | -4,258.58% |
| Sep 30, 2025 | -1,721.62% |
| Jun 30, 2025 | -1,484.53% |
| Mar 31, 2025 | -1,956.57% |
| Dec 31, 2024 | -1,637.47% |
| Sep 30, 2024 | 28.52% |
| Jun 30, 2024 | -3,051.09% |
| Dec 31, 2022 | -1,869,700.00% |
| Sep 30, 2022 | -342.22% |
| Dec 31, 2020 | -2,061.97% |
| Sep 30, 2020 | -1,674.53% |
| Jun 30, 2020 | -1,448.48% |
| Mar 31, 2020 | -59.46% |
| Dec 31, 2019 | -2,188.72% |
| Sep 30, 2019 | 53.81% |
| Jun 30, 2019 | -977.76% |
| Mar 31, 2019 | 80.16% |
| Dec 31, 2018 | -88.22% |
AC Immune Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ACIU&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ACIU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ACIU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();