AC Immune (ACIU) Operating Margin (2015 - 2026)
AC Immune (ACIU) posted quarterly Operating Margin of 1321.54% for Q1 2026, up 63503.0% year-over-year from N/an in Q1 2025, and up 68.97% quarter-over-quarter from 4258.58% in Q4 2025.
AC Immune (ACIU) Operating Margin (2015 - 2026) Analysis & Trends
AC Immune (ACIU) has reported Operating Margin for 10 consecutive years, with 1321.54% the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Margin rose 63503.0% year-over-year to 1321.54%; the TTM figure through Mar 2026 stood at 1749.24% (down 157246.0% YoY), while the FY2025 annual figure was 1940.05%, down 174825.0% from the prior year.
- Operating Margin grew to 1321.54% in Q1 2026 per ACIU's latest filing, from 4258.58% in the prior quarter.
- Across five years, Operating Margin topped out at 28.52% in Q3 2024 and bottomed at 53420.0% in Q4 2022.
- Historically, Operating Margin has averaged 6916.81% across 4 years, with a median of 1679.54% in 2024.
- On a YoY basis, Operating Margin climbed as much as 156656 bps in 2025 and fell as far as 262111 bps in 2025.
- AC Immune's Operating Margin stood at 53420.0% in 2022, then jumped by 97 bps to 1637.47% in 2024, then slumped by 160 bps to 4258.58% in 2025, then soared by 69 bps to 1321.54% in 2026.
- Business Quant data shows ACIU's Operating Margin at 1321.54% in Q1 2026, 4258.58% in Q4 2025, and 1721.62% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 31.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 19.06% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -105.20% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 19.75% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 17.93% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -0.36% |
| 10 | AC Immune | 253.89 Mn | 253.89 Mn | - | 7.89% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 7.89% |
| Mar 31, 2026 | -1,321.54% |
| Dec 31, 2025 | -4,258.58% |
| Sep 30, 2025 | -1,721.62% |
| Jun 30, 2025 | -1,484.53% |
| Mar 31, 2025 | -1,956.57% |
| Dec 31, 2024 | -1,637.47% |
| Sep 30, 2024 | 28.52% |
| Jun 30, 2024 | -3,051.09% |
| Dec 31, 2022 | -53,420.00% |
| Sep 30, 2022 | -345.21% |
| Dec 31, 2020 | -2,061.97% |
| Sep 30, 2020 | -1,674.53% |
| Jun 30, 2020 | -1,448.48% |
| Mar 31, 2020 | -59.46% |
| Dec 31, 2019 | -2,188.72% |
| Sep 30, 2019 | 817.14% |
| Jun 30, 2019 | -977.76% |
| Mar 31, 2019 | 80.16% |
| Dec 31, 2018 | -1,292.42% |