AC Immune (ACIU) Operating Margin (2015 - 2026)
AC Immune's (ACIU) quarterly Operating Margin came in at 1321.54% in Q1 2026, up 63503.0% year-on-year from N/an in Q1 2025, and up 68.97% on a QoQ basis from 4258.58% in Q4 2025.
AC Immune (ACIU) Operating Margin (2015 - 2026) Analysis & Trends
AC Immune (ACIU) has 10 years of Operating Margin data on file, last reported at 1321.54% in Q1 2026.
- On a quarterly basis, Operating Margin rose 63503.0% year-over-year to 1321.54% in Q1 2026; TTM through Mar 2026 was 1749.24%, a 157246.0% decrease from a year earlier, with the FY2025 full-year figure at 1940.05%, down 174825.0% from the prior year.
- Operating Margin for Q1 2026 stood at 1321.54%, up from 4258.58% in the prior quarter.
- Over the last five years, Operating Margin for ACIU reached as high as 28.52% in Q3 2024 and fell as low as 4258.58% in Q4 2025.
- Historically, Operating Margin has averaged 1749.79% across 4 years, with a median of 1637.47% in 2024.
- On a YoY basis, Operating Margin climbed as much as 156656 bps in 2025 and fell as far as 262111 bps in 2025.
- Year by year, Operating Margin stood at 345.21% in 2022, then plunged by 374 bps to 1637.47% in 2024, then slumped by 160 bps to 4258.58% in 2025, then surged by 69 bps to 1321.54% in 2026.
- Per Business Quant data, the three most recent Operating Margin figures were 1321.54% in Q1 2026, 4258.58% in Q4 2025, and 1721.62% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | AC Immune | 225.68 Mn | 225.68 Mn | - | -1,321.54% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,321.54% |
| Dec 31, 2025 | -4,258.58% |
| Sep 30, 2025 | -1,721.62% |
| Jun 30, 2025 | -1,484.53% |
| Mar 31, 2025 | -1,956.57% |
| Dec 31, 2024 | -1,637.47% |
| Sep 30, 2024 | 28.52% |
| Jun 30, 2024 | -3,051.09% |
| Sep 30, 2022 | -345.21% |
| Dec 31, 2020 | -2,061.97% |
| Sep 30, 2020 | -1,674.53% |
| Jun 30, 2020 | -1,448.48% |
| Mar 31, 2020 | -59.46% |
| Dec 31, 2019 | -2,188.72% |
| Sep 30, 2019 | 817.14% |
| Jun 30, 2019 | -977.76% |
| Mar 31, 2019 | 80.16% |
| Dec 31, 2018 | -1,292.42% |
| Sep 30, 2018 | -528.03% |
| Jun 30, 2018 | -570.51% |