Xencor (XNCR) Net Margin (2013 - 2026)
Xencor's Net Margin was -42.42% in Q2 2026, up 28.26 percentage points from -70.69% a year earlier and up 2812.23 percentage points from the prior quarter.
Xencor (XNCR) Net Margin (2013 - 2026) Analysis & Trends
On a trailing twelve-month basis, Xencor's Net Margin was -155.59% through Jun 30, 2026, down 39.15 percentage points year-over-year; for FY2025, it came in at -73.20%, up 137.33 percentage points from FY2024.
- Net Margin shows a five-year change of -16.69 percentage points (FY2020 to FY2025).
- In earlier years, Net Margin was -210.53% in FY2024 (-134.28 pp), -76.24% in FY2023 (-42.72 pp), -33.52% in FY2022 (-63.56 pp) and 30.04% in FY2021 (+86.54 pp).
- Quarterly Net Margin has moved between -2854.65% (Q1 2026) and 47.44% (Q4 2021) over five years.
- Compared with a year earlier, Net Margin was higher in five of the last eight quarters, with an average year-over-year change of -264.54 percentage points.
- The best year-over-year quarter for Net Margin over five years was Q1 2025 (a gain of 311.16 percentage points); the worst was Q1 2026 (a drop of 2706.73 percentage points).
- Per Business Quant data, XNCR's Net Margin in the three quarters before Q2 2026 was -2854.65% (Q1 2026), -23.56% (Q4 2025) and -28.70% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 32.99% |
| 10 | Xencor | 1.86 Bn | 274.02 Mn | - | -42.42% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -42.42% |
| Mar 31, 2026 | -2,854.65% |
| Dec 31, 2025 | -23.56% |
| Sep 30, 2025 | -28.70% |
| Jun 30, 2025 | -70.69% |
| Mar 31, 2025 | -147.92% |
| Dec 31, 2024 | -86.29% |
| Sep 30, 2024 | -260.10% |
| Jun 30, 2024 | -281.66% |
| Mar 31, 2024 | -459.09% |
| Dec 31, 2023 | -51.30% |
| Sep 30, 2023 | -40.99% |
| Jun 30, 2023 | -48.23% |
| Mar 31, 2023 | -319.81% |
| Dec 31, 2022 | -55.75% |
| Sep 30, 2022 | -120.00% |
| Jun 30, 2022 | -112.50% |
| Mar 31, 2022 | 27.60% |
| Dec 31, 2021 | 47.44% |
| Sep 30, 2021 | -204.02% |
Xencor Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=XNCR&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "XNCR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=XNCR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();