Xencor (XNCR) Net Margin (2013 - 2026)
Xencor (XNCR) posted quarterly Net Margin of 2855.09% for Q1 2026, down 270642.0% year-over-year from N/an in Q1 2025, and down 12017.73% quarter-over-quarter from 23.56% in Q4 2025.
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Xencor (XNCR) Net Margin (2013 - 2026) Analysis & Trends
Xencor (XNCR) has reported Net Margin for 14 consecutive years, with 2855.09% the latest figure, recorded in Q1 2026.
- In Q1 2026, Net Margin fell 270642.0% year-over-year to 2855.09%; the TTM figure through Mar 2026 stood at 177.12% (down 1120.0% YoY), while the FY2025 annual figure was 73.37%, up 14071.0% from the prior year.
- Net Margin eased to 2855.09% in Q1 2026 per XNCR's latest filing, from 23.56% in the prior quarter.
- Across five years, Net Margin topped out at 27.6% in Q1 2022 and bottomed at 2855.09% in Q1 2026.
- Historically, Net Margin has averaged 297.03% across 5 years, with a median of 112.5% in 2022.
- Annual changes were most pronounced in 2025 — Net Margin surged 31463 bps — and 2026, when it sank 270642 bps.
- Xencor's Net Margin stood at 55.72% in 2022, then grew by 7 bps to 51.57% in 2023, then slumped by 70 bps to 87.51% in 2024, then soared by 73 bps to 23.56% in 2025, then sank by 12018 bps to 2855.09% in 2026.
- Business Quant data shows XNCR's Net Margin at 2855.09% in Q1 2026, 23.56% in Q4 2025, and 28.7% in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 31.16% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -539.31% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 13.90% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 12.74% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 12.09% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -3.12% |
| 10 | Xencor | 2.02 Bn | 1.65 Bn | - | -42.40% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -42.40% |
| Mar 31, 2026 | -2,855.09% |
| Dec 31, 2025 | -23.56% |
| Sep 30, 2025 | -28.70% |
| Jun 30, 2025 | -70.57% |
| Mar 31, 2025 | -148.68% |
| Dec 31, 2024 | -87.51% |
| Sep 30, 2024 | -266.59% |
| Jun 30, 2024 | -287.71% |
| Mar 31, 2024 | -463.31% |
| Dec 31, 2023 | -51.62% |
| Sep 30, 2023 | -40.99% |
| Jun 30, 2023 | -57.12% |
| Mar 31, 2023 | -304.48% |
| Dec 31, 2022 | -55.82% |
| Sep 30, 2022 | -120.00% |
| Jun 30, 2022 | -112.50% |
| Mar 31, 2022 | 27.60% |
| Dec 31, 2021 | 47.44% |
| Sep 30, 2021 | -204.02% |