Xencor (XNCR) Operating Income (2013 - 2026)

Xencor (XNCR) reported Operating Income of -$77.9 million for Q1 2026, down 80.31% year-over-year from -$395.4 million in Q1 2025, and down 45.19% quarter-over-quarter from -$53.6 million in Q4 2025.

Xencor (XNCR) Operating Income (2013 - 2026) Analysis & Trends

Xencor (XNCR) has 14 years of Operating Income data on file, last reported at -$77.9 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$77.9 million, down 80.31% year-over-year; the trailing twelve-month figure through Mar 2026 was -$212.2 million (down 27.11% YoY), and the FY2025 annual result was -$177.5 million, up 0.51% from the prior year.
  • Operating Income fell to -$77.9 million in Q1 2026 per XNCR's latest filing, from -$53.6 million in the prior quarter.
  • Over five years, Operating Income peaked at $26.5 million in Q1 2022 and troughed at -$77.9 million in Q1 2026.
  • A 5-year average of -$38.2 million and a median of -$42.6 million in 2022 frame the typical range for Operating Income.
  • On a YoY basis, Operating Income climbed as much as 268.87% in 2022 and fell as far as 408.13% in 2022.
  • A 5-year view of Operating Income shows it stood at -$42.6 million in 2022, then soared by 35.79% to -$27.4 million in 2023, then jumped by 51.82% to -$13.2 million in 2024, then tumbled by 306.95% to -$53.6 million in 2025, then plunged by 45.19% to -$77.9 million in 2026.
  • Business Quant data shows XNCR's Operating Income at -$77.9 million in Q1 2026, -$53.6 million in Q4 2025, and -$47.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Xencor 953.38 Mn 878.64 Mn - -77.86 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -77.86 Mn
Dec 31, 2025 -53.63 Mn
Sep 30, 2025 -47.52 Mn
Jun 30, 2025 -33.17 Mn
Mar 31, 2025 -43.18 Mn
Dec 31, 2024 -13.18 Mn
Sep 30, 2024 -55.20 Mn
Jun 30, 2024 -55.37 Mn
Mar 31, 2024 -54.66 Mn
Dec 31, 2023 -27.35 Mn
Sep 30, 2023 -18.27 Mn
Jun 30, 2023 -26.00 Mn
Mar 31, 2023 -60.74 Mn
Dec 31, 2022 -42.59 Mn
Sep 30, 2022 -38.35 Mn
Jun 30, 2022 -28.00 Mn
Mar 31, 2022 26.47 Mn
Dec 31, 2021 91.65 Mn
Sep 30, 2021 -41.30 Mn
Jun 30, 2021 9.09 Mn