Xencor (XNCR) Operating Income (2013 - 2026)
Xencor (XNCR) reported Operating Income of -$77.9 million for Q1 2026, down 80.31% year-over-year from -$395.4 million in Q1 2025, and down 45.19% quarter-over-quarter from -$53.6 million in Q4 2025.
Xencor (XNCR) Operating Income (2013 - 2026) Analysis & Trends
Xencor (XNCR) has 14 years of Operating Income data on file, last reported at -$77.9 million in Q1 2026.
- Operating Income for Q1 2026 came in at -$77.9 million, down 80.31% year-over-year; the trailing twelve-month figure through Mar 2026 was -$212.2 million (down 27.11% YoY), and the FY2025 annual result was -$177.5 million, up 0.51% from the prior year.
- Operating Income fell to -$77.9 million in Q1 2026 per XNCR's latest filing, from -$53.6 million in the prior quarter.
- Over five years, Operating Income peaked at $26.5 million in Q1 2022 and troughed at -$77.9 million in Q1 2026.
- A 5-year average of -$38.2 million and a median of -$42.6 million in 2022 frame the typical range for Operating Income.
- On a YoY basis, Operating Income climbed as much as 268.87% in 2022 and fell as far as 408.13% in 2022.
- A 5-year view of Operating Income shows it stood at -$42.6 million in 2022, then soared by 35.79% to -$27.4 million in 2023, then jumped by 51.82% to -$13.2 million in 2024, then tumbled by 306.95% to -$53.6 million in 2025, then plunged by 45.19% to -$77.9 million in 2026.
- Business Quant data shows XNCR's Operating Income at -$77.9 million in Q1 2026, -$53.6 million in Q4 2025, and -$47.5 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Xencor | 953.38 Mn | 878.64 Mn | - | -77.86 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -77.86 Mn |
| Dec 31, 2025 | -53.63 Mn |
| Sep 30, 2025 | -47.52 Mn |
| Jun 30, 2025 | -33.17 Mn |
| Mar 31, 2025 | -43.18 Mn |
| Dec 31, 2024 | -13.18 Mn |
| Sep 30, 2024 | -55.20 Mn |
| Jun 30, 2024 | -55.37 Mn |
| Mar 31, 2024 | -54.66 Mn |
| Dec 31, 2023 | -27.35 Mn |
| Sep 30, 2023 | -18.27 Mn |
| Jun 30, 2023 | -26.00 Mn |
| Mar 31, 2023 | -60.74 Mn |
| Dec 31, 2022 | -42.59 Mn |
| Sep 30, 2022 | -38.35 Mn |
| Jun 30, 2022 | -28.00 Mn |
| Mar 31, 2022 | 26.47 Mn |
| Dec 31, 2021 | 91.65 Mn |
| Sep 30, 2021 | -41.30 Mn |
| Jun 30, 2021 | 9.09 Mn |