Xencor (XNCR) Operating Income (2013 - 2026)

Xencor's (XNCR) quarterly Operating Income came in at -$77.9 million in Q1 2026, down 80.31% year-on-year from -$395.4 million in Q1 2025, and down 45.19% on a QoQ basis from -$53.6 million in Q4 2025.

Xencor (XNCR) Operating Income (2013 - 2026) Analysis & Trends

Xencor (XNCR) has 14 years of Operating Income data on file, last reported at -$77.9 million in Q1 2026.

  • On a quarterly basis, Operating Income fell 80.31% year-over-year to -$77.9 million in Q1 2026; TTM through Mar 2026 was -$212.2 million, a 27.11% decrease from a year earlier, with the FY2025 full-year figure at -$177.5 million, up 0.51% from the prior year.
  • Operating Income for Q1 2026 stood at -$77.9 million, down from -$53.6 million in the prior quarter.
  • Over the last five years, Operating Income for XNCR reached as high as $26.5 million in Q1 2022 and fell as low as -$77.9 million in Q1 2026.
  • Historically, Operating Income has averaged -$38.2 million across 5 years, with a median of -$42.6 million in 2022.
  • On a YoY basis, Operating Income climbed as much as 268.87% in 2022 and fell as far as 408.13% in 2022.
  • Year by year, Operating Income stood at -$42.6 million in 2022, then soared by 35.79% to -$27.4 million in 2023, then jumped by 51.82% to -$13.2 million in 2024, then plunged by 306.95% to -$53.6 million in 2025, then sank by 45.19% to -$77.9 million in 2026.
  • Per Business Quant data, the three most recent Operating Income figures were -$77.9 million in Q1 2026, -$53.6 million in Q4 2025, and -$47.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Xencor 1.47 Bn 1.09 Bn - -77.86 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -77.86 Mn
Dec 31, 2025 -53.63 Mn
Sep 30, 2025 -47.52 Mn
Jun 30, 2025 -33.17 Mn
Mar 31, 2025 -43.18 Mn
Dec 31, 2024 -13.18 Mn
Sep 30, 2024 -55.20 Mn
Jun 30, 2024 -55.37 Mn
Mar 31, 2024 -54.66 Mn
Dec 31, 2023 -27.35 Mn
Sep 30, 2023 -18.27 Mn
Jun 30, 2023 -26.00 Mn
Mar 31, 2023 -60.74 Mn
Dec 31, 2022 -42.59 Mn
Sep 30, 2022 -38.35 Mn
Jun 30, 2022 -28.00 Mn
Mar 31, 2022 26.47 Mn
Dec 31, 2021 91.65 Mn
Sep 30, 2021 -41.30 Mn
Jun 30, 2021 9.09 Mn