Xencor Inc (XNCR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

19,299,284Shares held by institutions

$219,239,866Value of institutional holdings

113.82%Institutional ownership %

7.63%Shares Changed QoQ

193No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Xencor Inc (NASDAQ:XNCR) has 200 institutional investors with active 13F positions as of December 2025.

Their combined ownership stood at 107.9% of outstanding shares in December 2025, down from 112.5% in September 2025.
Their total shares held in XNCR increased 1.08% from the prior quarter, while the number of investors in Xencor increased 4.17% year over year.
During the quarter, 89 of these 200 funds increased positions in XNCR, 76 reduced exposure, and 35 held steady.
In total, institutional investors held 80.28Mn shares in Xencor as of December 2025, up by 855.13K shares quarter on quarter, and up 4.11Mn shares year over year.
As of December 31, 2025, the biggest holder of Xencor is BlackRock, Inc. at 11.93Mn shares, representing 16.03% of shares outstanding.
The most significant purchases of XNCR for the quarter ending December 2025 came from BVF INC/IL (4.39Mn), Defilade Capital Management, L.P. (1.41Mn), State Street Corp (833.42K), Lynx1 Capital Management LP (705.56K), Jefferies Financial Group Inc. (620.44K).
The largest sales of XNCR for the quarter ending December 2025 came from EcoR1 Capital, LLC (2.89Mn), Nantahala Capital Management, LLC (935.36K), Bank Of America Corp /De/ (878.25K), BRAIDWELL LP (787.11K), UBS Group AG (537.25K).
Per Business Quant, the top 10 investors in XNCR for the quarter ending December 2025 include BlackRock, Inc. (11.93Mn), PRIMECAP MANAGEMENT CO/CA/ (10.22Mn), VANGUARD GROUP INC (7.17Mn), BVF INC/IL (7.13Mn), RTW INVESTMENTS, LP (6.78Mn), State Street Corp (4.51Mn), EcoR1 Capital, LLC (3.25Mn), TCG Crossover Management, LLC (2.45Mn), GEODE CAPITAL MANAGEMENT, LLC (1.75Mn), Morgan Stanley (1.51Mn).

200 Institutional Holders

19,299,284 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	119,991	1.02%	$0.00
PRIMECAP MANAGEMENT CO/CA/	31 Dec, 2025	-456,700	-4.28%	$0.00
TCG Crossover Management, LLC	31 Dec, 2025	0	0.00%	$0.00
Johnson & Johnson	31 Dec, 2025	0	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	61,692	0.87%	$0.00
Defilade Capital Management, L.P.	31 Dec, 2025	1,414,755	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-396,678	-52.48%	$0.00
BVF INC/IL	31 Dec, 2025	4,393,579	160.34%	$0.00
Lynx1 Capital Management LP	31 Dec, 2025	705,558	0.00%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	21,074	101.01%	$0.00
RTW INVESTMENTS, LP	31 Dec, 2025	556,407	8.94%	$0.00
UBS Group AG	31 Dec, 2025	-537,246	-45.71%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	15,057	93.91%	$0.00
State Street Corp	31 Dec, 2025	833,423	22.69%	$0.00
Erste Asset Management GmbH	31 Dec, 2025	100,000	26.30%	$0.00
EcoR1 Capital, LLC	31 Dec, 2025	-2,893,655	-47.09%	$0.00
BRAIDWELL LP	31 Dec, 2025	-787,114	-63.16%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	24,093	1.39%	$0.00
Woodline Partners LP	31 Dec, 2025	0	0.00%	$0.00
Morgan Stanley	31 Dec, 2025	607,890	67.48%	$0.00

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