Xilio Therapeutics (XLO) Operating Expenses (2020 - 2026)
Xilio Therapeutics (XLO) recorded Operating Expenses of $22.18 million in Q2 2026, down 1.2% from $22.45 million a year earlier and down 17.1% from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) Operating Expenses (2020 - 2026) Analysis & Trends
On a TTM basis, Xilio Therapeutics' Operating Expenses came in at $95.46 million as of Jun 30, 2026, up 33.3% year-over-year; for FY2025, it came in at $85.75 million, up 28.1% from FY2024.
- Annual Operating Expenses has a five-year compound annual growth rate of 9.5% (FY2020 to FY2025).
- Across earlier years, Operating Expenses came in at $66.93 million in FY2024 (-15.4%), $79.13 million in FY2023 (-11.2%), $89.15 million in FY2022 (+18.8%) and $75.04 million in FY2021 (+37.5%).
- Quarterly Operating Expenses has ranged from $15.35 million in Q4 2024 to $26.76 million in Q1 2026 over the past five years.
- On a year-over-year basis, Operating Expenses rose in four of the last eight quarters, with growth averaging 19.8%.
- Peak year-over-year performance for Operating Expenses in the last five years was growth of 66.2% in Q4 2025, against a decline of 25.7% in Q1 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at $26.76 million (Q1 2026), $25.52 million (Q4 2025) and $21 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,133.08 Bn | 1,101.67 Bn | 19.71 Bn | 7.95 Bn |
| 2 | Johnson & Johnson | 616.40 Bn | 534.93 Bn | 17.26 Bn | 10.12 Bn |
| 3 | AbbVie | 501.19 Bn | 474.31 Bn | 12.70 Bn | 10.56 Bn |
| 4 | Merck | 367.18 Bn | 321.56 Bn | 12.21 Bn | 12.80 Bn |
| 5 | Novartis Ag | 297.99 Bn | 261.98 Bn | 11.24 Bn | 6.09 Bn |
| 6 | Astrazeneca | 261.67 Bn | 235.36 Bn | 12.86 Bn | 9.70 Bn |
| 7 | Amgen | 235.57 Bn | 190.97 Bn | 7.24 Bn | 6.54 Bn |
| 8 | Gilead Sciences | 190.62 Bn | 164.82 Bn | 6.22 Bn | 18.20 Bn |
| 9 | Pfizer | 169.63 Bn | 116.28 Bn | 10.94 Bn | 6.68 Bn |
| 10 | Xilio Therapeutics | 165.72 Mn | -361.95 Mn | - | 22.18 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 22.18 Mn |
| Mar 31, 2026 | 26.76 Mn |
| Dec 31, 2025 | 25.52 Mn |
| Sep 30, 2025 | 21.00 Mn |
| Jun 30, 2025 | 22.45 Mn |
| Mar 31, 2025 | 16.78 Mn |
| Dec 31, 2024 | 15.35 Mn |
| Sep 30, 2024 | 17.03 Mn |
| Jun 30, 2024 | 17.06 Mn |
| Mar 31, 2024 | 17.49 Mn |
| Dec 31, 2023 | 18.13 Mn |
| Sep 30, 2023 | 17.36 Mn |
| Jun 30, 2023 | 20.12 Mn |
| Mar 31, 2023 | 23.53 Mn |
| Dec 31, 2022 | 23.17 Mn |
| Sep 30, 2022 | 20.21 Mn |
| Jun 30, 2022 | 24.55 Mn |
| Mar 31, 2022 | 21.22 Mn |
| Dec 31, 2021 | 19.56 Mn |
| Sep 30, 2021 | 15.96 Mn |
API Access
Xilio Therapeutics Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();