Xilio Therapeutics (XLO) Operating Expenses (2020 - 2026)

Xilio Therapeutics (XLO) reported Operating Expenses of $26.8 million for Q1 2026, up 59.47% on a YoY basis from $16.8 million in Q1 2025, and up 4.85% sequentially from $25.5 million in Q4 2025.

Xilio Therapeutics (XLO) Operating Expenses (2020 - 2026) Analysis & Trends

Xilio Therapeutics (XLO) has 7 years of Operating Expenses data on file, last reported at $26.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 59.47% year-over-year to $26.8 million; the trailing twelve-month figure through Mar 2026 stood at $95.7 million (up 44.56% YoY), and the FY2025 full-year result was $85.7 million, up 28.12% from the prior year.
  • Operating Expenses climbed to $26.8 million in Q1 2026, from $25.5 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $26.8 million in Q1 2026 to a low of $15.4 million in Q4 2024.
  • A 5-year average of $20.5 million and a median of $20.2 million in 2022 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses decreased 25.67% in 2024 and soared 66.23% in 2025, its largest moves.
  • Tracing XLO's Operating Expenses over 5 years: stood at $23.2 million in 2022, then retreated by 21.74% to $18.1 million in 2023, then fell by 15.32% to $15.4 million in 2024, then soared by 66.23% to $25.5 million in 2025, then climbed by 4.85% to $26.8 million in 2026.
  • Business Quant data shows XLO's Operating Expenses at $26.8 million in Q1 2026, $25.5 million in Q4 2025, and $21.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 66,741.39 Bn 66,741.11 Bn - -28.01 Mn
2 Nanobiotix 1,935.05 Bn 1,934.98 Bn - -
3 Akari Therapeutics 1,045.06 Bn 1,045.06 Bn - 15.76 Mn
4 BeOne Medicines 468.98 Bn 464.19 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 123.24 Bn 115.99 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 70.45 Bn 61.70 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 63.04 Bn 63.04 Bn - 32.68 Mn
8 Argenx Se 55.79 Bn 50.60 Bn 1.41 Bn 2.89 Bn
9 Alnylam Pharmaceuticals 37.79 Bn 34.78 Bn 959.66 Mn 898.54 Mn
10 Xilio Therapeutics 147.13 Mn -3.17 Mn - 26.76 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 26.76 Mn
Dec 31, 2025 25.52 Mn
Sep 30, 2025 21.00 Mn
Jun 30, 2025 22.45 Mn
Mar 31, 2025 16.78 Mn
Dec 31, 2024 15.35 Mn
Sep 30, 2024 17.03 Mn
Jun 30, 2024 17.06 Mn
Mar 31, 2024 17.49 Mn
Dec 31, 2023 18.13 Mn
Sep 30, 2023 17.36 Mn
Jun 30, 2023 20.12 Mn
Mar 31, 2023 23.53 Mn
Dec 31, 2022 23.17 Mn
Sep 30, 2022 20.21 Mn
Jun 30, 2022 24.55 Mn
Mar 31, 2022 21.22 Mn
Dec 31, 2021 19.56 Mn
Sep 30, 2021 15.96 Mn
Jun 30, 2021 23.01 Mn