Valion Bio VBIO
NASDAQ VBIO
$2.51 -0.29 (-10.36%)
At close: Oct 1, 2026 · 4:00 PM EDT

Valion Bio (VBIO) Operating Margin (2021 - 2025)

Updated

Valion Bio's Operating Margin came in at -1700.68% for Q3 2025, down 564.97 percentage points from -1135.71% a year earlier but up 250.48 percentage points from the prior quarter.

Analysis

Valion Bio (VBIO) Operating Margin (2021 - 2025) Analysis & Trends

Over the trailing twelve months to Sep 30, 2025, Valion Bio reported Operating Margin of -1237.55%, down 566.50 percentage points year-over-year; for FY2024, it came in at -573.85%, up 127.26 percentage points from FY2023.

  • Operating Margin carries a three-year change of -125.72 percentage points (FY2021 to FY2024).
  • Going back by year, Operating Margin was -701.11% in FY2023 (-152.30 pp), -548.80% in FY2022 (-100.67 pp) and -448.13% in FY2021.
  • The five-year range for quarterly Operating Margin is -2151.43% (Q1 2025) to -165.56% (Q4 2024).
  • Year-over-year, Operating Margin has declined for three consecutive quarters, with an average year-over-year change of -363.64 percentage points over the last eight quarters.
  • The fastest year-over-year change in Operating Margin over five years came in Q4 2024 (a gain of 463.02 percentage points), and the weakest in Q1 2025 (a drop of 1708.02 percentage points).
  • Business Quant data shows VBIO's Operating Margin at -1951.16% (Q2 2025), -2151.43% (Q1 2025) and -165.56% (Q4 2024) in the three quarters before Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Johnson & Johnson 638.12 Bn 556.64 Bn 17.26 Bn 28.21%
2 AbbVie 462.60 Bn 435.75 Bn 12.70 Bn 37.86%
3 Merck 358.70 Bn 313.13 Bn 12.21 Bn -3.52%
4 Novartis Ag 272.16 Bn 228.03 Bn 11.24 Bn 32.97%
5 Astrazeneca 250.36 Bn 223.92 Bn 12.86 Bn 20.57%
6 Amgen 227.87 Bn 183.27 Bn 7.24 Bn 34.95%
7 Gilead Sciences 184.97 Bn 159.08 Bn 6.22 Bn -133.21%
8 Pfizer 162.61 Bn 109.56 Bn 10.94 Bn 28.37%
9 Vertex Pharmaceuticals 132.45 Bn 104.46 Bn 2.84 Bn 37.40%
10 Valion Bio 378,559.99 -19.06 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2025 -1,700.68%
Jun 30, 2025 -1,951.16%
Mar 31, 2025 -2,151.43%
Dec 31, 2024 -165.56%
Sep 30, 2024 -1,135.71%
Jun 30, 2024 -904.29%
Mar 31, 2024 -443.41%
Dec 31, 2023 -628.57%
Sep 30, 2023 -624.11%
Jun 30, 2023 -1,319.88%
Mar 31, 2023 -562.77%
Dec 31, 2022 -552.94%
Sep 30, 2022 -541.72%
Jun 30, 2022 -571.59%
Mar 31, 2022 -523.60%
Dec 31, 2021 -589.20%
Sep 30, 2021 -443.68%
Jun 30, 2021 -393.66%
Mar 31, 2021 -327.24%
API Access

Valion Bio Operating Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=operating-margin&ticker=VBIO&period=max&api_key=YOUR_API_KEY