Vertex Pharmaceuticals (VRTX) Operating Expenses (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Operating Expenses of $1.8 billion in Q1 2026, down 6.82% quarter-over-quarter from $2.0 billion in Q4 2025, and down 13.61% on a YoY basis from $2.1 billion in Q1 2025.

Vertex Pharmaceuticals (VRTX) Operating Expenses (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Operating Expenses history runs 18 years deep, the most recent figure standing at $1.8 billion for Q1 2026.

  • In Q1 2026, Operating Expenses fell 13.61% year-over-year to $1.8 billion; the TTM figure through Mar 2026 stood at $7.5 billion (down 36.36% YoY), while the FY2025 annual figure was $7.8 billion, down 30.44% from the prior year.
  • Operating Expenses was $1.8 billion for Q1 2026 at Vertex Pharmaceuticals, down from $2.0 billion in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $6.2 billion in Q2 2024 to a low of $1.1 billion in Q1 2022.
  • Historically, Operating Expenses has averaged $1.9 billion across 5 years, with a median of $1.6 billion in 2023.
  • The sharpest annual moves came in 2024 and 2025: Operating Expenses soared 319.98% in 2024, then plunged 70.56% in 2025.
  • A 5-year view of Operating Expenses shows it stood at $1.3 billion in 2022, then rose by 20.49% to $1.5 billion in 2023, then increased by 23.33% to $1.9 billion in 2024, then grew by 5.2% to $2.0 billion in 2025, then dropped by 6.82% to $1.8 billion in 2026.
  • The last three Operating Expenses figures came in at $1.8 billion (Q1 2026), $2.0 billion (Q4 2025), and $1.9 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 2.96 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.85 Bn
Dec 31, 2025 1.98 Bn
Sep 30, 2025 1.89 Bn
Jun 30, 2025 1.81 Bn
Mar 31, 2025 2.14 Bn
Dec 31, 2024 1.89 Bn
Sep 30, 2024 1.66 Bn
Jun 30, 2024 6.16 Bn
Mar 31, 2024 1.55 Bn
Dec 31, 2023 1.53 Bn
Sep 30, 2023 1.45 Bn
Jun 30, 2023 1.47 Bn
Mar 31, 2023 1.60 Bn
Dec 31, 2022 1.27 Bn
Sep 30, 2022 1.21 Bn
Jun 30, 2022 1.09 Bn
Mar 31, 2022 1.06 Bn
Dec 31, 2021 1.19 Bn
Sep 30, 2021 929.60 Mn
Jun 30, 2021 1.83 Bn