Vertex Pharmaceuticals (VRTX) Operating Expenses (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Operating Expenses came in at $1.8 billion in Q1 2026, down 13.61% year-on-year from $2.1 billion in Q1 2025, and down 6.82% quarter-over-quarter from $2.0 billion in Q4 2025.

Vertex Pharmaceuticals (VRTX) Operating Expenses (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Operating Expenses history runs 18 years deep, the most recent figure standing at $1.8 billion for Q1 2026.

  • On a quarterly basis, Operating Expenses fell 13.61% year-over-year to $1.8 billion in Q1 2026; TTM through Mar 2026 was $7.5 billion, a 36.36% decrease from a year earlier, with the FY2025 full-year figure at $7.8 billion, down 30.44% from the prior year.
  • Operating Expenses declined to $1.8 billion in Q1 2026 per VRTX's latest filing, from $2.0 billion in the prior quarter.
  • Across five years, Operating Expenses topped out at $6.2 billion in Q2 2024 and bottomed at $1.1 billion in Q1 2022.
  • The 5-year median for Operating Expenses is $1.6 billion (2023), against an average of $1.9 billion.
  • Across the five-year window, Operating Expenses surged 319.98% in 2024 and plunged 70.56% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $1.3 billion in 2022, then rose by 20.49% to $1.5 billion in 2023, then increased by 23.33% to $1.9 billion in 2024, then grew by 5.2% to $2.0 billion in 2025, then dropped by 6.82% to $1.8 billion in 2026.
  • Per Business Quant, the three latest VRTX Operating Expenses figures stand at $1.8 billion (Q1 2026), $2.0 billion (Q4 2025), and $1.9 billion (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 898.54 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.85 Bn
Dec 31, 2025 1.98 Bn
Sep 30, 2025 1.89 Bn
Jun 30, 2025 1.81 Bn
Mar 31, 2025 2.14 Bn
Dec 31, 2024 1.89 Bn
Sep 30, 2024 1.66 Bn
Jun 30, 2024 6.16 Bn
Mar 31, 2024 1.55 Bn
Dec 31, 2023 1.53 Bn
Sep 30, 2023 1.45 Bn
Jun 30, 2023 1.47 Bn
Mar 31, 2023 1.60 Bn
Dec 31, 2022 1.27 Bn
Sep 30, 2022 1.21 Bn
Jun 30, 2022 1.09 Bn
Mar 31, 2022 1.06 Bn
Dec 31, 2021 1.19 Bn
Sep 30, 2021 929.60 Mn
Jun 30, 2021 1.83 Bn