Septerna (SEPN) Operating Expenses (2023 - 2026)
Septerna (SEPN) recorded quarterly Operating Expenses of $6.2 million in Q1 2026, down 84.66% quarter-over-quarter from $40.1 million in Q4 2025, and up 25.35% on a YoY basis from $4.9 million in Q1 2025.
Septerna (SEPN) Operating Expenses (2023 - 2026) Analysis & Trends
Septerna's Operating Expenses history runs 4 years deep, the most recent figure standing at $6.2 million for Q1 2026.
- In Q1 2026, Operating Expenses rose 25.35% year-over-year to $6.2 million; the TTM figure through Mar 2026 stood at $94.3 million (down 18.68% YoY), while the FY2025 annual figure was $114.2 million, up 39.5% from the prior year.
- Operating Expenses was $6.2 million for Q1 2026 at Septerna, down from $40.1 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $69.9 million in Q4 2024 to a low of -$34.2 million in Q4 2023.
- Historically, Operating Expenses has averaged $18.5 million across 4 years, with a median of $18.4 million in 2024.
- The sharpest annual moves came in 2024 and 2025: Operating Expenses jumped 304.29% in 2024, then sank 68.93% in 2025.
- A 4-year view of Operating Expenses shows it stood at -$34.2 million in 2023, then surged by 304.29% to $69.9 million in 2024, then sank by 42.55% to $40.1 million in 2025, then plunged by 84.66% to $6.2 million in 2026.
- The last three Operating Expenses figures came in at $6.2 million (Q1 2026), $40.1 million (Q4 2025), and $18.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Septerna | 1.62 Bn | 1.62 Bn | - | 6.16 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 6.16 Mn |
| Dec 31, 2025 | 40.14 Mn |
| Sep 30, 2025 | 18.88 Mn |
| Jun 30, 2025 | 29.10 Mn |
| Mar 31, 2025 | 4.91 Mn |
| Dec 31, 2024 | 69.87 Mn |
| Sep 30, 2024 | 22.73 Mn |
| Jun 30, 2024 | 18.44 Mn |
| Mar 31, 2024 | 15.81 Mn |
| Dec 31, 2023 | -34.20 Mn |
| Sep 30, 2023 | 12.07 Mn |