Septerna (SEPN) Operating Expenses (2023 - 2025)

Septerna has reported Operating Expenses over the past 3 years, most recently at $40.1 million for Q4 2025.

  • Quarterly results put Operating Expenses at $40.1 million for Q4 2025, up 61.01% from a year ago — trailing twelve months through Dec 2025 was $101.1 million (up 23.45% YoY), and the annual figure for FY2025 was $114.2 million, up 39.5%.
  • Operating Expenses for Q4 2025 was $40.1 million at Septerna, up from $5.7 million in the prior quarter.
  • Over the last five years, Operating Expenses for SEPN hit a ceiling of $40.1 million in Q4 2025 and a floor of -$34.2 million in Q4 2023.
  • Median Operating Expenses over the past 3 years was $20.6 million (2024), compared with a mean of $16.1 million.
  • Biggest five-year swings in Operating Expenses: surged 172.9% in 2024 and later tumbled 74.77% in 2025.
  • Septerna's Operating Expenses stood at -$34.2 million in 2023, then surged by 172.9% to $24.9 million in 2024, then soared by 61.01% to $40.1 million in 2025.
  • The last three reported values for Operating Expenses were $40.1 million (Q4 2025), $5.7 million (Q3 2025), and $29.1 million (Q2 2025) per Business Quant data.