Septerna (SEPN) Operating Expenses (2023 - 2026)

Septerna's Operating Expenses history runs 4 years deep, the most recent figure standing at $6.2 million for Q1 2026.

• On a quarterly basis, Operating Expenses rose 25.35% year-over-year to $6.2 million in Q1 2026; TTM through Mar 2026 was $152.4 million, a 55.91% increase from a year earlier, with the FY2025 full-year figure at $114.2 million, up 39.5% from the prior year.
• Operating Expenses eased to $6.2 million in Q1 2026 per SEPN's latest filing, from $98.2 million in the prior quarter.
• Across five years, Operating Expenses topped out at $98.2 million in Q4 2025 and bottomed at -$34.2 million in Q4 2023.
• The 4-year median for Operating Expenses is $15.8 million (2024), against an average of $22.2 million.
• Biggest YoY gain for Operating Expenses was 317.54% in 2025; the steepest drop was 68.93% in 2025.
• Year by year, Operating Expenses stood at -$34.2 million in 2023, then surged by 304.29% to $69.9 million in 2024, then surged by 40.62% to $98.2 million in 2025, then tumbled by 93.73% to $6.2 million in 2026.
• Per Business Quant, the three latest SEPN Operating Expenses figures stand at $6.2 million (Q1 2026), $98.2 million (Q4 2025), and $18.9 million (Q3 2025).