Septerna (SEPN) Operating Expenses (2023 - 2026)
Septerna (SEPN) recorded Operating Expenses of $43.58 million in Q2 2026, up 49.8% from $29.1 million a year earlier and up 9.4% from the prior quarter.
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Analysis
Septerna (SEPN) Operating Expenses (2023 - 2026) Analysis & Trends
On a TTM basis, Septerna's Operating Expenses came in at $142.43 million as of Jun 30, 2026, up 38.4% year-over-year; for FY2025, it was $114.25 million, up 39.5% from FY2024.
- Across earlier years, Operating Expenses came in at $81.9 million in FY2024 and -$1.92 million in FY2023.
- The Q2 2026 figure is the highest quarterly Operating Expenses in data going back to Q3 2023.
- On a year-over-year basis, Operating Expenses has increased for three consecutive quarters, with growth averaging 51.1% over the last seven quarters.
- Per Business Quant, the preceding three quarters came in at $39.82 million (Q1 2026), $40.14 million (Q4 2025) and $18.88 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 10.12 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 10.56 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 12.80 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | -6.09 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | -9.70 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 6.54 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 18.20 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 6.68 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 2.09 Bn |
| 10 | Septerna | 1.81 Bn | 1.81 Bn | - | 43.58 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 43.58 Mn |
| Mar 31, 2026 | 39.82 Mn |
| Dec 31, 2025 | 40.14 Mn |
| Sep 30, 2025 | 18.88 Mn |
| Jun 30, 2025 | 29.10 Mn |
| Mar 31, 2025 | 26.13 Mn |
| Dec 31, 2024 | 24.93 Mn |
| Sep 30, 2024 | 22.73 Mn |
| Jun 30, 2024 | 18.44 Mn |
| Mar 31, 2024 | 15.81 Mn |
| Dec 31, 2023 | -34.20 Mn |
| Sep 30, 2023 | 12.07 Mn |
API Access
Septerna Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=SEPN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "SEPN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=SEPN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();