Septerna (SEPN) Operating Expenses (2023 - 2026)
Septerna (SEPN) posted quarterly Operating Expenses of $6.2 million for Q1 2026, up 25.35% year-over-year from $4.9 million in Q1 2025, and down 93.73% quarter-over-quarter from $98.2 million in Q4 2025.
Septerna (SEPN) Operating Expenses (2023 - 2026) Analysis & Trends
Septerna's Operating Expenses history runs 4 years deep, the most recent figure standing at $6.2 million for Q1 2026.
- In Q1 2026, Operating Expenses rose 25.35% year-over-year to $6.2 million; the TTM figure through Mar 2026 stood at $152.4 million (up 55.91% YoY), while the FY2025 annual figure was $114.2 million, up 39.5% from the prior year.
- Operating Expenses for Q1 2026 stood at $6.2 million, down from $98.2 million in the prior quarter.
- The five-year high for Operating Expenses was $98.2 million in Q4 2025, with the low at -$34.2 million in Q4 2023.
- The 4-year median for Operating Expenses is $15.8 million (2024), against an average of $22.2 million.
- Peak annual rise in Operating Expenses reached 317.54% in 2025, while the deepest fall reached 68.93% in 2025.
- Septerna's Operating Expenses stood at -$34.2 million in 2023, then jumped by 304.29% to $69.9 million in 2024, then jumped by 40.62% to $98.2 million in 2025, then plunged by 93.73% to $6.2 million in 2026.
- Business Quant data shows SEPN's Operating Expenses at $6.2 million in Q1 2026, $98.2 million in Q4 2025, and $18.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Septerna | 2.08 Bn | 2.08 Bn | - | 43.58 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 43.58 Mn |
| Mar 31, 2026 | 6.16 Mn |
| Dec 31, 2025 | 98.25 Mn |
| Sep 30, 2025 | 18.88 Mn |
| Jun 30, 2025 | 29.10 Mn |
| Mar 31, 2025 | 4.91 Mn |
| Dec 31, 2024 | 69.87 Mn |
| Sep 30, 2024 | 4.52 Mn |
| Jun 30, 2024 | 18.44 Mn |
| Mar 31, 2024 | 15.81 Mn |
| Dec 31, 2023 | -34.20 Mn |
| Sep 30, 2023 | 12.07 Mn |