Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026)

Rhythm Pharmaceuticals' (RYTM) quarterly Operating Expenses came in at $112.5 million in Q1 2026, up 41.11% year-on-year from $79.7 million in Q1 2025, and up 7.82% on a QoQ basis from $104.3 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 11 years of Operating Expenses data on file, last reported at $112.5 million in Q1 2026.

  • On a quarterly basis, Operating Expenses rose 41.11% year-over-year to $112.5 million in Q1 2026; TTM through Mar 2026 was $414.5 million, a 33.94% increase from a year earlier, with the FY2025 full-year figure at $381.8 million, down 3.5% from the prior year.
  • Operating Expenses for Q1 2026 stood at $112.5 million, up from $104.3 million in the prior quarter.
  • Over the last five years, Operating Expenses for RYTM reached as high as $165.9 million in Q1 2024 and fell as low as $43.6 million in Q3 2022.
  • Historically, Operating Expenses has averaged $79.7 million across 5 years, with a median of $69.6 million in 2024.
  • Across the five-year window, Operating Expenses surged 159.15% in 2024 and plunged 51.94% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $50.9 million in 2022, then rose by 28.7% to $65.5 million in 2023, then rose by 26.85% to $83.1 million in 2024, then climbed by 25.55% to $104.3 million in 2025, then climbed by 7.82% to $112.5 million in 2026.
  • Per Business Quant data, the three most recent Operating Expenses figures were $112.5 million in Q1 2026, $104.3 million in Q4 2025, and $104.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Rhythm Pharmaceuticals 6.98 Bn 6.64 Bn 52.96 Mn 112.47 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 112.47 Mn
Dec 31, 2025 104.32 Mn
Sep 30, 2025 103.95 Mn
Jun 30, 2025 93.80 Mn
Mar 31, 2025 79.71 Mn
Dec 31, 2024 83.09 Mn
Sep 30, 2024 77.14 Mn
Jun 30, 2024 69.56 Mn
Mar 31, 2024 165.85 Mn
Dec 31, 2023 65.50 Mn
Sep 30, 2023 66.46 Mn
Jun 30, 2023 65.83 Mn
Mar 31, 2023 64.00 Mn
Dec 31, 2022 50.89 Mn
Sep 30, 2022 43.55 Mn
Jun 30, 2022 54.16 Mn
Mar 31, 2022 54.19 Mn
Dec 31, 2021 52.81 Mn
Sep 30, 2021 45.27 Mn
Jun 30, 2021 40.71 Mn