Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026)

Rhythm Pharmaceuticals (RYTM) reported Operating Expenses of $112.5 million for Q1 2026, up 41.11% year-over-year from $79.7 million in Q1 2025, and up 7.82% quarter-over-quarter from $104.3 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 11 years of Operating Expenses data on file, last reported at $112.5 million in Q1 2026.

  • Operating Expenses for Q1 2026 came in at $112.5 million, up 41.11% year-over-year; the trailing twelve-month figure through Mar 2026 was $414.5 million (up 33.94% YoY), and the FY2025 annual result was $381.8 million, down 3.5% from the prior year.
  • Operating Expenses climbed to $112.5 million in Q1 2026 per RYTM's latest filing, from $104.3 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $165.9 million in Q1 2024 and troughed at $43.6 million in Q3 2022.
  • A 5-year average of $79.7 million and a median of $69.6 million in 2024 frame the typical range for Operating Expenses.
  • The sharpest annual moves came in 2024 and 2025: Operating Expenses jumped 159.15% in 2024, then slumped 51.94% in 2025.
  • A 5-year view of Operating Expenses shows it stood at $50.9 million in 2022, then climbed by 28.7% to $65.5 million in 2023, then climbed by 26.85% to $83.1 million in 2024, then rose by 25.55% to $104.3 million in 2025, then rose by 7.82% to $112.5 million in 2026.
  • Business Quant data shows RYTM's Operating Expenses at $112.5 million in Q1 2026, $104.3 million in Q4 2025, and $104.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Rhythm Pharmaceuticals 6.59 Bn 6.25 Bn 52.96 Mn 112.47 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 112.47 Mn
Dec 31, 2025 104.32 Mn
Sep 30, 2025 103.95 Mn
Jun 30, 2025 93.80 Mn
Mar 31, 2025 79.71 Mn
Dec 31, 2024 83.09 Mn
Sep 30, 2024 77.14 Mn
Jun 30, 2024 69.56 Mn
Mar 31, 2024 165.85 Mn
Dec 31, 2023 65.50 Mn
Sep 30, 2023 66.46 Mn
Jun 30, 2023 65.83 Mn
Mar 31, 2023 64.00 Mn
Dec 31, 2022 50.89 Mn
Sep 30, 2022 43.55 Mn
Jun 30, 2022 54.16 Mn
Mar 31, 2022 54.19 Mn
Dec 31, 2021 52.81 Mn
Sep 30, 2021 45.27 Mn
Jun 30, 2021 40.71 Mn