Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) posted quarterly Operating Expenses of $112.5 million for Q1 2026, up 41.11% year-over-year from $79.7 million in Q1 2025, and up 7.82% quarter-over-quarter from $104.3 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Operating Expenses (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has reported Operating Expenses for 11 consecutive years, with $112.5 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Expenses rose 41.11% year-over-year to $112.5 million; the TTM figure through Mar 2026 stood at $414.5 million (up 33.94% YoY), while the FY2025 annual figure was $381.8 million, down 3.5% from the prior year.
- Operating Expenses grew to $112.5 million in Q1 2026 per RYTM's latest filing, from $104.3 million in the prior quarter.
- Across five years, Operating Expenses topped out at $165.9 million in Q1 2024 and bottomed at $43.6 million in Q3 2022.
- Historically, Operating Expenses has averaged $79.7 million across 5 years, with a median of $69.6 million in 2024.
- Annual changes were most pronounced in 2024 — Operating Expenses jumped 159.15% — and 2025, when it slumped 51.94%.
- Rhythm Pharmaceuticals' Operating Expenses stood at $50.9 million in 2022, then grew by 28.7% to $65.5 million in 2023, then grew by 26.85% to $83.1 million in 2024, then gained by 25.55% to $104.3 million in 2025, then gained by 7.82% to $112.5 million in 2026.
- Business Quant data shows RYTM's Operating Expenses at $112.5 million in Q1 2026, $104.3 million in Q4 2025, and $104.0 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Rhythm Pharmaceuticals | 7.95 Bn | 7.62 Bn | 62.32 Mn | 119.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 119.81 Mn |
| Mar 31, 2026 | 112.47 Mn |
| Dec 31, 2025 | 104.32 Mn |
| Sep 30, 2025 | 103.95 Mn |
| Jun 30, 2025 | 93.80 Mn |
| Mar 31, 2025 | 79.71 Mn |
| Dec 31, 2024 | 83.09 Mn |
| Sep 30, 2024 | 77.14 Mn |
| Jun 30, 2024 | 69.56 Mn |
| Mar 31, 2024 | 165.85 Mn |
| Dec 31, 2023 | 65.50 Mn |
| Sep 30, 2023 | 66.46 Mn |
| Jun 30, 2023 | 65.83 Mn |
| Mar 31, 2023 | 64.00 Mn |
| Dec 31, 2022 | 50.89 Mn |
| Sep 30, 2022 | 43.55 Mn |
| Jun 30, 2022 | 54.16 Mn |
| Mar 31, 2022 | 54.19 Mn |
| Dec 31, 2021 | 52.81 Mn |
| Sep 30, 2021 | 45.27 Mn |