Pyxis Oncology (PYXS) Research & Development (2020 - 2025)
Pyxis Oncology (PYXS) reported Research & Development of $21.7 million for Q4 2025, up 54.81% year-over-year from $14.0 million in Q4 2024, and up 21.92% quarter-over-quarter from $17.8 million in Q3 2025.
Pyxis Oncology (PYXS) Research & Development (2020 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has 6 years of Research & Development data on file, last reported at $21.7 million in Q4 2025.
- Research & Development for Q4 2025 came in at $21.7 million, up 54.81% year-over-year; the trailing twelve-month figure through Dec 2025 was $73.7 million (up 25.45% YoY), and the FY2025 annual result was $73.7 million, up 25.45% from the prior year.
- Research & Development climbed to $21.7 million in Q4 2025 per PYXS's latest filing, from $17.8 million in the prior quarter.
- Over five years, Research & Development peaked at $32.8 million in Q1 2021 and troughed at $3.2 million in Q2 2021.
- A 5-year average of $16.0 million and a median of $15.9 million in 2023 frame the typical range for Research & Development.
- The sharpest annual moves came in 2022 and 2023: Research & Development jumped 435.73% in 2022, then tumbled 61.12% in 2023.
- A 5-year view of Research & Development shows it stood at $7.2 million in 2021, then soared by 313.15% to $29.9 million in 2022, then plunged by 61.12% to $11.6 million in 2023, then advanced by 20.82% to $14.0 million in 2024, then surged by 54.81% to $21.7 million in 2025.
- Business Quant data shows PYXS's Research & Development at $21.7 million in Q4 2025, $17.8 million in Q3 2025, and $17.1 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.32 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 15.66 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 626,092.00 |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -101.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -2.30 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 1.46 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 357,444.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 961.60 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -58.00 Mn |
| 10 | Pyxis Oncology | 125.84 Mn | 108.95 Mn | 8.65 Mn | 21.71 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 21.71 Mn |
| Sep 30, 2025 | 17.81 Mn |
| Jun 30, 2025 | 17.13 Mn |
| Mar 31, 2025 | 17.04 Mn |
| Dec 31, 2024 | 14.02 Mn |
| Sep 30, 2024 | 17.74 Mn |
| Jun 30, 2024 | 13.95 Mn |
| Mar 31, 2024 | 13.03 Mn |
| Dec 31, 2023 | 11.61 Mn |
| Sep 30, 2023 | 14.69 Mn |
| Jun 30, 2023 | 11.39 Mn |
| Mar 31, 2023 | 11.90 Mn |
| Dec 31, 2022 | 29.85 Mn |
| Sep 30, 2022 | 19.03 Mn |
| Jun 30, 2022 | 17.17 Mn |
| Mar 31, 2022 | 20.07 Mn |
| Dec 31, 2021 | 7.23 Mn |
| Sep 30, 2021 | 7.85 Mn |
| Jun 30, 2021 | 3.21 Mn |
| Mar 31, 2021 | 32.77 Mn |