Pyxis Oncology (PYXS) Research & Development (2020 - 2025)

Pyxis Oncology (PYXS) reported Research & Development of $21.7 million for Q4 2025, up 54.81% year-over-year from $14.0 million in Q4 2024, and up 21.92% quarter-over-quarter from $17.8 million in Q3 2025.

Pyxis Oncology (PYXS) Research & Development (2020 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 6 years of Research & Development data on file, last reported at $21.7 million in Q4 2025.

  • Research & Development for Q4 2025 came in at $21.7 million, up 54.81% year-over-year; the trailing twelve-month figure through Dec 2025 was $73.7 million (up 25.45% YoY), and the FY2025 annual result was $73.7 million, up 25.45% from the prior year.
  • Research & Development climbed to $21.7 million in Q4 2025 per PYXS's latest filing, from $17.8 million in the prior quarter.
  • Over five years, Research & Development peaked at $32.8 million in Q1 2021 and troughed at $3.2 million in Q2 2021.
  • A 5-year average of $16.0 million and a median of $15.9 million in 2023 frame the typical range for Research & Development.
  • The sharpest annual moves came in 2022 and 2023: Research & Development jumped 435.73% in 2022, then tumbled 61.12% in 2023.
  • A 5-year view of Research & Development shows it stood at $7.2 million in 2021, then soared by 313.15% to $29.9 million in 2022, then plunged by 61.12% to $11.6 million in 2023, then advanced by 20.82% to $14.0 million in 2024, then surged by 54.81% to $21.7 million in 2025.
  • Business Quant data shows PYXS's Research & Development at $21.7 million in Q4 2025, $17.8 million in Q3 2025, and $17.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.32 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 15.66 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 626,092.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -101.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -2.30 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 1.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 357,444.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 961.60 Mn
9 Abivax 91.96 Bn 91.96 Bn - -58.00 Mn
10 Pyxis Oncology 125.84 Mn 108.95 Mn 8.65 Mn 21.71 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 21.71 Mn
Sep 30, 2025 17.81 Mn
Jun 30, 2025 17.13 Mn
Mar 31, 2025 17.04 Mn
Dec 31, 2024 14.02 Mn
Sep 30, 2024 17.74 Mn
Jun 30, 2024 13.95 Mn
Mar 31, 2024 13.03 Mn
Dec 31, 2023 11.61 Mn
Sep 30, 2023 14.69 Mn
Jun 30, 2023 11.39 Mn
Mar 31, 2023 11.90 Mn
Dec 31, 2022 29.85 Mn
Sep 30, 2022 19.03 Mn
Jun 30, 2022 17.17 Mn
Mar 31, 2022 20.07 Mn
Dec 31, 2021 7.23 Mn
Sep 30, 2021 7.85 Mn
Jun 30, 2021 3.21 Mn
Mar 31, 2021 32.77 Mn