Prime Medicine PRME Institutional Ownership

NASDAQ PRME

$3.81 -0.11 (-2.81%)

At close: Oct 21, 2026 · 4:00 PM EDT

Institutions by Trading Activity

188 Institutions

Increased 88 46.8%

Unchanged 33 17.6%

Reduced 67 35.6%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

59.01%

▲+4.55 pp QoQ

Shares Held by Institutions

106.65Mn

of 180.74Mn outstanding

▲+8.42% QoQ

Shares Outstanding

180.74Mn

74.08Mn held outside 13F filers

Institutional Investors

188

filed 13F for Jun 2026

▼-3 vs prior quarter

Net Shares Added (QoQ)

+8.28Mn

accumulated since last quarter

Value of Holdings

$418.08Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Prime Medicine, Inc. (NASDAQ:PRME) was reported as a holding by 188 institutional investors in 13F filings for the quarter ended June 30, 2026.

Together they owned 59.01% of the outstanding stock in Q2 2026, up from 54.46% a quarter earlier.
Total shares held in Prime Medicine rose 8.42% from Q1 2026, while the number of holders rose 59.32% from Q2 2025.
Looking at the 188 holders of PRME individually, 88 added to their positions, 67 reduced their stakes and 33 left their positions unchanged.
Combined, institutional investors held 106.65Mn shares of PRME as of Q2 2026, up 8.28Mn from the prior quarter and up 49.43Mn from a year earlier.
Alphabet Inc. was the top holder of Prime Medicine as of June 30, 2026, with 16.56Mn shares, or 9.16% of shares outstanding.
The largest position increases in PRME for Q2 2026 were by Goldman Sachs Group Inc (+2.46Mn shares), ARK Investment Management LLC (+2.1Mn shares), Citadel Advisors LLC (+1.72Mn shares), State Street Corp (+1.23Mn shares) and BlackRock, Inc. (+1.1Mn shares).
Among holders that kept a stake in Prime Medicine, the biggest sellers in Q2 2026 were D. E. Shaw & Co., Inc. (-744.68K shares), Renaissance Technologies LLC (-623.63K shares), Amova Asset Management Americas, Inc. (-533.77K shares), Sumitomo Mitsui Trust Group, Inc. (-527.81K shares) and HRT Financial LP (-451.26K shares).
Business Quant data shows the 10 biggest positions in Prime Medicine as of Q2 2026 were held by Alphabet Inc. (16.56Mn shares), BlackRock, Inc. (9.6Mn shares), ARK Investment Management LLC (8.35Mn shares), State Street Corp (7.58Mn shares), T. Rowe Price Investment Management, Inc. (5.24Mn shares), Vanguard Capital Management LLC (4.52Mn shares), Balyasny Asset Management L.P. (3.97Mn shares), Goldman Sachs Group Inc (3.43Mn shares), Casdin Capital, LLC (3.17Mn shares) and Woodline Partners LP (3Mn shares).

Form 13F Holdings

188 Institutional Holders

Report period 30 Jun, 2026

Total shares held 106.65Mn

Of outstanding 59.01%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Alphabet Inc.	0001652044	16,562,498	9.16%	0	0.00%	$61.12Mn
2	BlackRock, Inc.	0002012383	9,602,041	5.31%	▲1,100,333	+12.94%	$35.43Mn
3	ARK Investment Management LLC	0001697748	8,348,746	4.62%	▲2,101,919	+33.65%	$30.81Mn
4	State Street Corp	0000093751	7,576,460	4.19%	▲1,231,335	+19.41%	$27.96Mn
5	T. Rowe Price Investment Management, Inc.	0001897612	5,237,332	2.90%	▼244,561	-4.46%	$19.33K
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	4,522,640	2.50%	▲48,478	+1.08%	$16.69Mn
7	BALYASNY ASSET MANAGEMENT L.P.	0001218710	3,969,082	2.20%	▼154,283	-3.74%	$14.65Mn
8	Goldman Sachs Group Inc	0000886982	3,430,518	1.90%	▲2,460,093	+253.51%	$12.66Mn
9	Casdin Capital, LLC	0001534261	3,167,175	1.75%	0	0.00%	$11.69Mn
10	Woodline Partners LP	0001784547	3,003,904	1.66%	▲591	+0.02%	$11.08Mn
11	UBS Group AG	0001610520	2,794,689	1.55%	▼93,729	-3.24%	$10.31Mn
12	GEODE CAPITAL MANAGEMENT, LLC	0001214717	2,712,446	1.50%	▼31,254	-1.14%	$10.01Mn
13	Sumitomo Mitsui Trust Group, Inc.	0001475365	2,412,984	1.34%	▼527,809	-17.95%	$8.90Mn
14	Amova Asset Management Americas, Inc.	0001480751	2,407,018	1.33%	▼533,775	-18.15%	$8.86Mn
15	CITADEL ADVISORS LLC	0001423053	2,054,543	1.14%	▲1,718,185	+510.82%	$7.58Mn
16	ADAR1 Capital Management, LLC	0001940272	1,997,552	1.11%	▲24,270	+1.23%	$7.37Mn
17	FMR LLC	0000315066	1,761,884	0.97%	▼7,592	-0.43%	$6.50Mn
18	TWO SIGMA INVESTMENTS, LP	0001179392	1,524,511	0.84%	▼48,300	-3.07%	$5.63Mn
19	Redmile Group, LLC	0001425738	1,389,632	0.77%	▼201,200	-12.65%	$5.13Mn
20	FARALLON CAPITAL MANAGEMENT, L.L.C.	0000909661	1,240,843	0.69%	0	0.00%	$4.58Mn

Showing 1 to 20 of 188 holders