Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026)
Prelude Therapeutics (PRLD) reported Operating Expenses of $18.8 million for Q1 2026, down 45.8% on a YoY basis from $34.6 million in Q1 2025, and down 18.41% sequentially from $23.0 million in Q4 2025.
Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026) Analysis & Trends
Prelude Therapeutics (PRLD) has 8 years of Operating Expenses data on file, last reported at $18.8 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Expenses fell 45.8% year-over-year to $18.8 million; the trailing twelve-month figure through Mar 2026 stood at $100.9 million (down 31.38% YoY), and the FY2025 full-year result was $116.7 million, down 20.45% from the prior year.
- Operating Expenses slipped to $18.8 million in Q1 2026, from $23.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $37.8 million in Q4 2024 to a low of $18.8 million in Q1 2026.
- A 5-year average of $31.6 million and a median of $32.4 million in 2023 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses soared 37.88% in 2022 and slumped 45.8% in 2026, its largest moves.
- Tracing PRLD's Operating Expenses over 5 years: stood at $33.4 million in 2022, then increased by 11.96% to $37.4 million in 2023, then advanced by 1.21% to $37.8 million in 2024, then plunged by 39.24% to $23.0 million in 2025, then declined by 18.41% to $18.8 million in 2026.
- Business Quant data shows PRLD's Operating Expenses at $18.8 million in Q1 2026, $23.0 million in Q4 2025, and $26.9 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Prelude Therapeutics | 318.53 Mn | 173.93 Mn | - | 18.76 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 18.76 Mn |
| Dec 31, 2025 | 22.99 Mn |
| Sep 30, 2025 | 26.92 Mn |
| Jun 30, 2025 | 32.19 Mn |
| Mar 31, 2025 | 34.61 Mn |
| Dec 31, 2024 | 37.83 Mn |
| Sep 30, 2024 | 37.38 Mn |
| Jun 30, 2024 | 37.16 Mn |
| Mar 31, 2024 | 34.34 Mn |
| Dec 31, 2023 | 37.38 Mn |
| Sep 30, 2023 | 33.39 Mn |
| Jun 30, 2023 | 32.40 Mn |
| Mar 31, 2023 | 29.12 Mn |
| Dec 31, 2022 | 33.39 Mn |
| Sep 30, 2022 | 30.41 Mn |
| Jun 30, 2022 | 29.46 Mn |
| Mar 31, 2022 | 30.29 Mn |
| Dec 31, 2021 | 33.01 Mn |
| Sep 30, 2021 | 30.84 Mn |
| Jun 30, 2021 | 27.92 Mn |