Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026)
Prelude Therapeutics (PRLD) posted Operating Expenses of $18.8 million for Q1 2026, down 18.41% sequentially from $23.0 million in Q4 2025, and down 45.8% YoY from $34.6 million in Q1 2025.
Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026) Analysis & Trends
Prelude Therapeutics has reported Operating Expenses for 8 years, with the latest figure at $18.8 million in Q1 2026.
- Quarterly Operating Expenses fell 45.8% year-over-year to $18.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $100.9 million (down 31.38% YoY) and the FY2025 annual result came in at $116.7 million, down 20.45% from the prior year.
- Operating Expenses slipped to $18.8 million in Q1 2026 per PRLD's latest filing, from $23.0 million in the prior quarter.
- Over five years, Operating Expenses peaked at $37.8 million in Q4 2024 and troughed at $18.8 million in Q1 2026.
- A 5-year average of $31.6 million and a median of $32.4 million in 2023 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2022 and 2026: Operating Expenses surged 37.88% in 2022, then plunged 45.8% in 2026.
- Over 5 years, Operating Expenses stood at $33.4 million in 2022, then advanced by 11.96% to $37.4 million in 2023, then increased by 1.21% to $37.8 million in 2024, then tumbled by 39.24% to $23.0 million in 2025, then decreased by 18.41% to $18.8 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $18.8 million, $23.0 million, and $26.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Prelude Therapeutics | 442.91 Mn | 162.28 Mn | - | 21.16 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 21.16 Mn |
| Mar 31, 2026 | 18.76 Mn |
| Dec 31, 2025 | 22.99 Mn |
| Sep 30, 2025 | 26.92 Mn |
| Jun 30, 2025 | 32.19 Mn |
| Mar 31, 2025 | 34.61 Mn |
| Dec 31, 2024 | 37.83 Mn |
| Sep 30, 2024 | 37.38 Mn |
| Jun 30, 2024 | 37.16 Mn |
| Mar 31, 2024 | 34.34 Mn |
| Dec 31, 2023 | 37.38 Mn |
| Sep 30, 2023 | 33.39 Mn |
| Jun 30, 2023 | 32.40 Mn |
| Mar 31, 2023 | 29.12 Mn |
| Dec 31, 2022 | 33.39 Mn |
| Sep 30, 2022 | 30.41 Mn |
| Jun 30, 2022 | 29.46 Mn |
| Mar 31, 2022 | 30.29 Mn |
| Dec 31, 2021 | 33.01 Mn |
| Sep 30, 2021 | 30.84 Mn |