Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026)
Prelude Therapeutics' (PRLD) quarterly Operating Expenses came in at $18.8 million in Q1 2026, down 45.8% year-on-year from $34.6 million in Q1 2025, and down 18.41% quarter-over-quarter from $23.0 million in Q4 2025.
Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026) Analysis & Trends
Prelude Therapeutics has disclosed Operating Expenses across 8 years of filings, most recently posting $18.8 million for Q1 2026.
- Operating Expenses for Q1 2026 came in at $18.8 million, down 45.8% year-over-year; the trailing twelve-month figure through Mar 2026 was $100.9 million (down 31.38% YoY), and the FY2025 annual result was $116.7 million, down 20.45% from the prior year.
- Operating Expenses came in at $18.8 million for Q1 2026 at Prelude Therapeutics, down from $23.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $37.8 million in Q4 2024 to a low of $18.8 million in Q1 2026.
- The 5-year median for Operating Expenses is $32.4 million (2023), against an average of $31.6 million.
- Across the five-year window, Operating Expenses soared 37.88% in 2022 and plunged 45.8% in 2026, its largest moves.
- Prelude Therapeutics' Operating Expenses stood at $33.4 million in 2022, then rose by 11.96% to $37.4 million in 2023, then climbed by 1.21% to $37.8 million in 2024, then tumbled by 39.24% to $23.0 million in 2025, then fell by 18.41% to $18.8 million in 2026.
- The last three Operating Expenses figures came in at $18.8 million (Q1 2026), $23.0 million (Q4 2025), and $26.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -67.40 Mn |
| 10 | Prelude Therapeutics | 314.40 Mn | 169.80 Mn | - | 18.76 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 18.76 Mn |
| Dec 31, 2025 | 22.99 Mn |
| Sep 30, 2025 | 26.92 Mn |
| Jun 30, 2025 | 32.19 Mn |
| Mar 31, 2025 | 34.61 Mn |
| Dec 31, 2024 | 37.83 Mn |
| Sep 30, 2024 | 37.38 Mn |
| Jun 30, 2024 | 37.16 Mn |
| Mar 31, 2024 | 34.34 Mn |
| Dec 31, 2023 | 37.38 Mn |
| Sep 30, 2023 | 33.39 Mn |
| Jun 30, 2023 | 32.40 Mn |
| Mar 31, 2023 | 29.12 Mn |
| Dec 31, 2022 | 33.39 Mn |
| Sep 30, 2022 | 30.41 Mn |
| Jun 30, 2022 | 29.46 Mn |
| Mar 31, 2022 | 30.29 Mn |
| Dec 31, 2021 | 33.01 Mn |
| Sep 30, 2021 | 30.84 Mn |
| Jun 30, 2021 | 27.92 Mn |