Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026)
Prelude Therapeutics (PRLD) posted Operating Expenses of $18.8 million for Q1 2026, down 18.41% sequentially from $23.0 million in Q4 2025, and down 45.8% YoY from $34.6 million in Q1 2025.
Analysis
Prelude Therapeutics (PRLD) Operating Expenses (2019 - 2026) Analysis & Trends
Prelude Therapeutics has reported Operating Expenses for 8 years, with the latest figure at $18.8 million in Q1 2026.
- Quarterly Operating Expenses fell 45.8% year-over-year to $18.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $100.9 million (down 31.38% YoY) and the FY2025 annual result came in at $116.7 million, down 20.45% from the prior year.
- Operating Expenses slipped to $18.8 million in Q1 2026 per PRLD's latest filing, from $23.0 million in the prior quarter.
- Over five years, Operating Expenses peaked at $37.8 million in Q4 2024 and troughed at $18.8 million in Q1 2026.
- A 5-year average of $31.6 million and a median of $32.4 million in 2023 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2022 and 2026: Operating Expenses surged 37.88% in 2022, then plunged 45.8% in 2026.
- Over 5 years, Operating Expenses stood at $33.4 million in 2022, then advanced by 11.96% to $37.4 million in 2023, then increased by 1.21% to $37.8 million in 2024, then tumbled by 39.24% to $23.0 million in 2025, then decreased by 18.41% to $18.8 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $18.8 million, $23.0 million, and $26.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.87 Bn | 131.01 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 85.57 Bn | 77.57 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 63.51 Bn | 58.32 Bn | 1.37 Bn | -1.05 Bn |
| 4 | Moderna | 58.19 Bn | 53.05 Bn | 52.00 Mn | 960.00 Mn |
| 5 | Revolution Medicines | 44.07 Bn | 44.07 Bn | - | 505.13 Mn |
| 6 | BeOne Medicines | 39.99 Bn | 34.89 Bn | 1.53 Bn | 1.21 Bn |
| 7 | Alnylam Pharmaceuticals | 35.38 Bn | 32.07 Bn | 992.69 Mn | 1.06 Bn |
| 8 | Royalty Pharma | 28.42 Bn | 27.58 Bn | - | 541.02 Mn |
| 9 | Insmed | 27.41 Bn | 26.25 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Prelude Therapeutics | 539.17 Mn | 258.54 Mn | - | 21.16 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 21.16 Mn |
| Mar 31, 2026 | 18.76 Mn |
| Dec 31, 2025 | 22.99 Mn |
| Sep 30, 2025 | 26.92 Mn |
| Jun 30, 2025 | 32.19 Mn |
| Mar 31, 2025 | 34.61 Mn |
| Dec 31, 2024 | 37.83 Mn |
| Sep 30, 2024 | 37.38 Mn |
| Jun 30, 2024 | 37.16 Mn |
| Mar 31, 2024 | 34.34 Mn |
| Dec 31, 2023 | 37.38 Mn |
| Sep 30, 2023 | 33.39 Mn |
| Jun 30, 2023 | 32.40 Mn |
| Mar 31, 2023 | 29.12 Mn |
| Dec 31, 2022 | 33.39 Mn |
| Sep 30, 2022 | 30.41 Mn |
| Jun 30, 2022 | 29.46 Mn |
| Mar 31, 2022 | 30.29 Mn |
| Dec 31, 2021 | 33.01 Mn |
| Sep 30, 2021 | 30.84 Mn |