Pfizer PFE
NYSE PFE
$29.74 -0.38 (-1.25%)
As of: Oct 21, 2026 · 2:32 PM EDT

Pfizer (PFE) Operating Margin (2009 - 2026)

Updated

Pfizer's Operating Margin came in at 28.37% for Q2 2026, down 6.11 percentage points from 34.48% a year earlier and down 8.67 percentage points from the prior quarter.

Analysis

Pfizer (PFE) Operating Margin (2009 - 2026) Analysis & Trends

Over the trailing twelve months to Jun 28, 2026, Pfizer reported Operating Margin of 32.02%, up 0.54 percentage points year-over-year; for FY2025, it came in at 33.13%, up 5.14 percentage points from FY2024.

  • Operating Margin carries a five-year change of +3.64 percentage points (FY2020 to FY2025).
  • Going back by year, Operating Margin was 27.98% in FY2024 (+17.56 pp), 10.42% in FY2023 (-29.46 pp), 39.88% in FY2022 (+7.16 pp) and 32.73% in FY2021 (+3.24 pp).
  • The five-year range for quarterly Operating Margin is -20.25% (Q4 2023) to 47.01% (Q2 2022).
  • Year-over-year, Operating Margin increased in five of the last seven quarters, with an average year-over-year change of +8.53 percentage points.
  • The fastest year-over-year change in Operating Margin over five years came in Q4 2024 (a gain of 41.61 percentage points), and the weakest in Q2 2023 (a drop of 20.79 percentage points).
  • Business Quant data shows PFE's Operating Margin at 37.04% (Q1 2026), 24.56% (Q4 2025) and 38.81% (Q3 2025) in the three quarters before Q2 2026.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Eli Lilly 1,135.99 Bn 1,104.58 Bn 19.71 Bn 51.16%
2 Johnson & Johnson 616.90 Bn 535.42 Bn 17.26 Bn 28.21%
3 AbbVie 501.56 Bn 474.68 Bn 12.70 Bn 37.86%
4 Merck 367.41 Bn 321.79 Bn 12.21 Bn -3.52%
5 Novartis Ag 297.75 Bn 261.74 Bn 11.24 Bn 32.97%
6 Astrazeneca 261.45 Bn 235.13 Bn 12.86 Bn 20.57%
7 Amgen 236.48 Bn 191.88 Bn 7.24 Bn 34.95%
8 Gilead Sciences 190.56 Bn 164.76 Bn 6.22 Bn -133.21%
9 Pfizer 169.46 Bn 116.11 Bn 10.94 Bn 28.37%
10 Vertex Pharmaceuticals 133.29 Bn 105.29 Bn 2.84 Bn 37.40%
Historic Data

Historic Data

Download Data
DateValue
Jun 28, 2026 28.37%
Mar 29, 2026 37.04%
Dec 31, 2025 24.56%
Sep 28, 2025 38.81%
Jun 29, 2025 34.48%
Mar 30, 2025 36.15%
Dec 31, 2024 21.36%
Sep 29, 2024 35.50%
Jun 30, 2024 17.44%
Mar 31, 2024 36.36%
Dec 31, 2023 -20.25%
Oct 1, 2023 -14.27%
Jul 2, 2023 26.22%
Apr 2, 2023 41.77%
Dec 31, 2022 25.59%
Oct 2, 2022 45.45%
Jul 3, 2022 47.01%
Apr 3, 2022 41.27%
Dec 31, 2021 26.92%
Oct 3, 2021 32.77%
API Access

Pfizer Operating Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=operating-margin&ticker=PFE&period=max&api_key=YOUR_API_KEY