Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026)
Puma Biotechnology (PBYI) reported Operating Expenses of $48.6 million for Q1 2026, up 15.75% on a YoY basis from $42.0 million in Q1 2025, and down 16.63% quarter-over-quarter from $58.3 million in Q4 2025.
Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026) Analysis & Trends
Puma Biotechnology has reported Operating Expenses for 17 years, with the latest figure at $48.6 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Expenses rose 15.75% year-over-year to $48.6 million; the trailing twelve-month figure through Mar 2026 stood at $197.7 million (up 1.14% YoY), and the FY2025 full-year result was $191.1 million, down 4.23% from the prior year.
- Operating Expenses for Q1 2026 stood at $48.6 million, down from $58.3 million in the prior quarter.
- The five-year high for Operating Expenses was $58.5 million in Q3 2024, with the low at $42.0 million in Q1 2025.
- Historically, Operating Expenses has averaged $49.8 million across 5 years, with a median of $48.4 million in 2023.
- Annual changes were most pronounced in 2022 — Operating Expenses slumped 40.42% — and 2025, when it rose 27.64%.
- Puma Biotechnology's Operating Expenses stood at $55.7 million in 2022, then advanced by 3.09% to $57.4 million in 2023, then fell by 20.33% to $45.7 million in 2024, then grew by 27.64% to $58.3 million in 2025, then slipped by 16.63% to $48.6 million in 2026.
- The last three Operating Expenses figures came in at $48.6 million (Q1 2026), $58.3 million (Q4 2025), and $44.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Puma Biotechnology | 384.39 Mn | 282.84 Mn | 34.39 Mn | 48.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.64 Mn |
| Dec 31, 2025 | 58.35 Mn |
| Sep 30, 2025 | 44.90 Mn |
| Jun 30, 2025 | 45.80 Mn |
| Mar 31, 2025 | 42.02 Mn |
| Dec 31, 2024 | 45.71 Mn |
| Sep 30, 2024 | 58.46 Mn |
| Jun 30, 2024 | 49.26 Mn |
| Mar 31, 2024 | 46.07 Mn |
| Dec 31, 2023 | 57.38 Mn |
| Sep 30, 2023 | 47.53 Mn |
| Jun 30, 2023 | 49.68 Mn |
| Mar 31, 2023 | 48.41 Mn |
| Dec 31, 2022 | 55.66 Mn |
| Sep 30, 2022 | 54.71 Mn |
| Jun 30, 2022 | 47.46 Mn |
| Mar 31, 2022 | 46.48 Mn |
| Dec 31, 2021 | 48.53 Mn |
| Sep 30, 2021 | 55.20 Mn |
| Jun 30, 2021 | 70.02 Mn |