Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026)

Puma Biotechnology (PBYI) posted Operating Expenses of $48.6 million for Q1 2026, down 16.63% on a QoQ basis from $58.3 million in Q4 2025, and up 15.75% year-over-year from $42.0 million in Q1 2025.

Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026) Analysis & Trends

Puma Biotechnology's Operating Expenses history runs 17 years deep, the most recent figure standing at $48.6 million for Q1 2026.

  • Quarterly Operating Expenses rose 15.75% year-over-year to $48.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $197.7 million (up 1.14% YoY) and the FY2025 annual result came in at $191.1 million, down 4.23% from the prior year.
  • Operating Expenses was $48.6 million for Q1 2026 at Puma Biotechnology, down from $58.3 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $58.5 million in Q3 2024 and bottomed at $42.0 million in Q1 2025.
  • A 5-year average of $49.8 million and a median of $48.4 million in 2023 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses sank 40.42% — and 2025, when it climbed 27.64%.
  • Puma Biotechnology's Operating Expenses stood at $55.7 million in 2022, then grew by 3.09% to $57.4 million in 2023, then decreased by 20.33% to $45.7 million in 2024, then rose by 27.64% to $58.3 million in 2025, then declined by 16.63% to $48.6 million in 2026.
  • Business Quant data shows PBYI's Operating Expenses at $48.6 million in Q1 2026, $58.3 million in Q4 2025, and $44.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Puma Biotechnology 407.27 Mn 368.99 Mn 34.39 Mn 48.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 48.64 Mn
Dec 31, 2025 58.35 Mn
Sep 30, 2025 44.90 Mn
Jun 30, 2025 45.80 Mn
Mar 31, 2025 42.02 Mn
Dec 31, 2024 45.71 Mn
Sep 30, 2024 58.46 Mn
Jun 30, 2024 49.26 Mn
Mar 31, 2024 46.07 Mn
Dec 31, 2023 57.38 Mn
Sep 30, 2023 47.53 Mn
Jun 30, 2023 49.68 Mn
Mar 31, 2023 48.41 Mn
Dec 31, 2022 55.66 Mn
Sep 30, 2022 54.71 Mn
Jun 30, 2022 47.46 Mn
Mar 31, 2022 46.48 Mn
Dec 31, 2021 48.53 Mn
Sep 30, 2021 55.20 Mn
Jun 30, 2021 70.02 Mn