Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026)
Puma Biotechnology (PBYI) posted Operating Expenses of $48.6 million for Q1 2026, down 16.63% on a QoQ basis from $58.3 million in Q4 2025, and up 15.75% year-over-year from $42.0 million in Q1 2025.
Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026) Analysis & Trends
Puma Biotechnology's Operating Expenses history runs 17 years deep, the most recent figure standing at $48.6 million for Q1 2026.
- Quarterly Operating Expenses rose 15.75% year-over-year to $48.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $197.7 million (up 1.14% YoY) and the FY2025 annual result came in at $191.1 million, down 4.23% from the prior year.
- Operating Expenses was $48.6 million for Q1 2026 at Puma Biotechnology, down from $58.3 million in the prior quarter.
- Across five years, Operating Expenses topped out at $58.5 million in Q3 2024 and bottomed at $42.0 million in Q1 2025.
- A 5-year average of $49.8 million and a median of $48.4 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2022 — Operating Expenses sank 40.42% — and 2025, when it climbed 27.64%.
- Puma Biotechnology's Operating Expenses stood at $55.7 million in 2022, then grew by 3.09% to $57.4 million in 2023, then decreased by 20.33% to $45.7 million in 2024, then rose by 27.64% to $58.3 million in 2025, then declined by 16.63% to $48.6 million in 2026.
- Business Quant data shows PBYI's Operating Expenses at $48.6 million in Q1 2026, $58.3 million in Q4 2025, and $44.9 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 1.10 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.78 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 2.89 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 445.22 Mn |
| 10 | Puma Biotechnology | 407.27 Mn | 368.99 Mn | 34.39 Mn | 48.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.64 Mn |
| Dec 31, 2025 | 58.35 Mn |
| Sep 30, 2025 | 44.90 Mn |
| Jun 30, 2025 | 45.80 Mn |
| Mar 31, 2025 | 42.02 Mn |
| Dec 31, 2024 | 45.71 Mn |
| Sep 30, 2024 | 58.46 Mn |
| Jun 30, 2024 | 49.26 Mn |
| Mar 31, 2024 | 46.07 Mn |
| Dec 31, 2023 | 57.38 Mn |
| Sep 30, 2023 | 47.53 Mn |
| Jun 30, 2023 | 49.68 Mn |
| Mar 31, 2023 | 48.41 Mn |
| Dec 31, 2022 | 55.66 Mn |
| Sep 30, 2022 | 54.71 Mn |
| Jun 30, 2022 | 47.46 Mn |
| Mar 31, 2022 | 46.48 Mn |
| Dec 31, 2021 | 48.53 Mn |
| Sep 30, 2021 | 55.20 Mn |
| Jun 30, 2021 | 70.02 Mn |