Puma Biotechnology PBYI
NASDAQ PBYI
$9.55 +0.14 (+1.49%)
As of: Sep 4, 2026 · 3:59 PM EDT

Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026)

Puma Biotechnology's (PBYI) quarterly Operating Expenses came in at $48.6 million in Q1 2026, up 15.75% YoY from $42.0 million in Q1 2025, and down 16.63% on a QoQ basis from $58.3 million in Q4 2025.

Analysis

Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026) Analysis & Trends

Puma Biotechnology (PBYI) has 17 years of Operating Expenses data on file, last reported at $48.6 million in Q1 2026.

  • Quarterly Operating Expenses rose 15.75% year-over-year to $48.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $197.7 million (up 1.14% YoY) and the FY2025 annual result came in at $191.1 million, down 4.23% from the prior year.
  • Operating Expenses eased to $48.6 million in Q1 2026, from $58.3 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $58.5 million in Q3 2024 to a low of $42.0 million in Q1 2025.
  • A 5-year average of $49.8 million and a median of $48.4 million in 2023 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses slumped 40.42% — and 2025, when it rose 27.64%.
  • Tracing PBYI's Operating Expenses over 5 years: stood at $55.7 million in 2022, then advanced by 3.09% to $57.4 million in 2023, then fell by 20.33% to $45.7 million in 2024, then grew by 27.64% to $58.3 million in 2025, then slipped by 16.63% to $48.6 million in 2026.
  • The last three Operating Expenses figures came in at $48.6 million (Q1 2026), $58.3 million (Q4 2025), and $44.9 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -1.05 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn 960.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 1.21 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 1.06 Bn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 541.02 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn 427.03 Mn
10 Puma Biotechnology 486.99 Mn 393.08 Mn 44.03 Mn 48.92 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 48.92 Mn
Mar 31, 2026 48.64 Mn
Dec 31, 2025 58.35 Mn
Sep 30, 2025 44.90 Mn
Jun 30, 2025 45.80 Mn
Mar 31, 2025 42.02 Mn
Dec 31, 2024 45.71 Mn
Sep 30, 2024 58.46 Mn
Jun 30, 2024 49.26 Mn
Mar 31, 2024 46.07 Mn
Dec 31, 2023 57.38 Mn
Sep 30, 2023 47.53 Mn
Jun 30, 2023 49.68 Mn
Mar 31, 2023 48.41 Mn
Dec 31, 2022 55.66 Mn
Sep 30, 2022 54.71 Mn
Jun 30, 2022 47.46 Mn
Mar 31, 2022 46.48 Mn
Dec 31, 2021 48.53 Mn
Sep 30, 2021 55.20 Mn