Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026)
Puma Biotechnology's (PBYI) quarterly Operating Expenses came in at $48.6 million in Q1 2026, up 15.75% YoY from $42.0 million in Q1 2025, and down 16.63% on a QoQ basis from $58.3 million in Q4 2025.
Analysis
Puma Biotechnology (PBYI) Operating Expenses (2010 - 2026) Analysis & Trends
Puma Biotechnology (PBYI) has 17 years of Operating Expenses data on file, last reported at $48.6 million in Q1 2026.
- Quarterly Operating Expenses rose 15.75% year-over-year to $48.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $197.7 million (up 1.14% YoY) and the FY2025 annual result came in at $191.1 million, down 4.23% from the prior year.
- Operating Expenses eased to $48.6 million in Q1 2026, from $58.3 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $58.5 million in Q3 2024 to a low of $42.0 million in Q1 2025.
- A 5-year average of $49.8 million and a median of $48.4 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2022 — Operating Expenses slumped 40.42% — and 2025, when it rose 27.64%.
- Tracing PBYI's Operating Expenses over 5 years: stood at $55.7 million in 2022, then advanced by 3.09% to $57.4 million in 2023, then fell by 20.33% to $45.7 million in 2024, then grew by 27.64% to $58.3 million in 2025, then slipped by 16.63% to $48.6 million in 2026.
- The last three Operating Expenses figures came in at $48.6 million (Q1 2026), $58.3 million (Q4 2025), and $44.9 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | -1.05 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 960.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 505.13 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 1.21 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 1.06 Bn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 541.02 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Puma Biotechnology | 486.99 Mn | 393.08 Mn | 44.03 Mn | 48.92 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 48.92 Mn |
| Mar 31, 2026 | 48.64 Mn |
| Dec 31, 2025 | 58.35 Mn |
| Sep 30, 2025 | 44.90 Mn |
| Jun 30, 2025 | 45.80 Mn |
| Mar 31, 2025 | 42.02 Mn |
| Dec 31, 2024 | 45.71 Mn |
| Sep 30, 2024 | 58.46 Mn |
| Jun 30, 2024 | 49.26 Mn |
| Mar 31, 2024 | 46.07 Mn |
| Dec 31, 2023 | 57.38 Mn |
| Sep 30, 2023 | 47.53 Mn |
| Jun 30, 2023 | 49.68 Mn |
| Mar 31, 2023 | 48.41 Mn |
| Dec 31, 2022 | 55.66 Mn |
| Sep 30, 2022 | 54.71 Mn |
| Jun 30, 2022 | 47.46 Mn |
| Mar 31, 2022 | 46.48 Mn |
| Dec 31, 2021 | 48.53 Mn |
| Sep 30, 2021 | 55.20 Mn |