Marker Therapeutics (MRKR) Operating Margin (2017 - 2025)
Marker Therapeutics (MRKR) recorded Operating Margin of -170.74% in Q4 2025, up 0.75 percentage points from -171.48% a year earlier and up 2.57 percentage points from the prior quarter.
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Analysis
Marker Therapeutics (MRKR) Operating Margin (2017 - 2025) Analysis & Trends
For FY2025, Marker Therapeutics reported Operating Margin of -363.45%, down 194.76 percentage points from FY2024.
- Annual Operating Margin has a five-year change of +5413.71 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -168.69% in FY2024 (+271.69 pp), -440.37% in FY2023 (+122.90 pp), -563.28% in FY2022 (+2616.05 pp) and -3179.32% in FY2021 (+2597.84 pp).
- The Q4 2025 figure is the highest quarterly Operating Margin since Q3 2024.
- On a year-over-year basis, Operating Margin rose in three of the last seven quarters, with an average year-over-year change of -66.99 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 1117.62 percentage points in Q3 2024, against a drop of 1215.25 percentage points in Q1 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -173.30% (Q3 2025), -594.79% (Q2 2025) and -1420.14% (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 37.40% |
| 10 | Marker Therapeutics | 17.87 Mn | -42.04 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -170.74% |
| Sep 30, 2025 | -173.30% |
| Jun 30, 2025 | -594.79% |
| Mar 31, 2025 | -1,420.14% |
| Dec 31, 2024 | -171.48% |
| Sep 30, 2024 | -124.60% |
| Jun 30, 2024 | -197.40% |
| Mar 31, 2024 | -204.89% |
| Dec 31, 2023 | -278.06% |
| Sep 30, 2023 | -1,242.22% |
| Dec 31, 2022 | -400.28% |
| Sep 30, 2022 | -582.90% |
| Jun 30, 2022 | -666.47% |
| Mar 31, 2022 | -1,015.71% |
| Dec 31, 2020 | -25,616.37% |
| Jun 30, 2020 | -1,361.99% |
| Dec 31, 2019 | -2,515.10% |
| Jun 30, 2018 | -2,268.90% |
| Sep 30, 2017 | -2,179.30% |
API Access
Marker Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=MRKR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "MRKR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=MRKR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();