Vertex Pharmaceuticals (VRTX) Cash from Operations (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Cash from Operations came in at 1428100000.0 in Q1 2026, up 74.39% year-on-year from 818900000.0 in Q1 2025, and up 186.77% quarter-over-quarter from 498000000.0 in Q4 2025.

Vertex Pharmaceuticals (VRTX) Cash from Operations (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Cash from Operations history runs 18 years deep, the most recent figure standing at 1428100000.0 for Q1 2026.

  • On a quarterly basis, Cash from Operations rose 74.39% year-over-year to 1428100000.0 in Q1 2026; TTM through Mar 2026 was 4240600000.0, a 532.58% increase from a year earlier, with the FY2025 full-year figure at 3631400000.0, up 837.19% from the prior year.
  • Cash from Operations grew to 1428100000.0 in Q1 2026 per VRTX's latest filing, from 498000000.0 in the prior quarter.
  • Across five years, Cash from Operations topped out at 1428100000.0 in Q1 2026 and bottomed at 3753600000.0 in Q2 2024.
  • The 5-year median for Cash from Operations is 1073100000.0 (2025), against an average of 719652941.18.
  • Across the five-year window, Cash from Operations surged 670.76% in 2022 and sank 430.89% in 2024, its largest moves.
  • Year by year, Cash from Operations stood at 1078400000.0 in 2022, then plunged by 78.25% to 234600000.0 in 2023, then jumped by 149.19% to 584600000.0 in 2024, then decreased by 14.81% to 498000000.0 in 2025, then soared by 186.77% to 1428100000.0 in 2026.
  • Per Business Quant, the three latest VRTX Cash from Operations figures stand at 1428100000.0 (Q1 2026), 498000000.0 (Q4 2025), and 1241400000.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.59 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 201.34 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.43 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 1.08 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.17 Mn
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 70.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.43 Bn
Mar 31, 2026 1.43 Bn
Dec 31, 2025 498.00 Mn
Dec 31, 2025 498.00 Mn
Sep 30, 2025 1.24 Bn
Sep 30, 2025 1.24 Bn
Jun 30, 2025 1.07 Bn
Jun 30, 2025 1.07 Bn
Mar 31, 2025 818.90 Mn
Mar 31, 2025 818.90 Mn
Dec 31, 2024 584.60 Mn
Dec 31, 2024 584.60 Mn
Sep 30, 2024 1.37 Bn
Sep 30, 2024 1.37 Bn
Jun 30, 2024 -3.75 Bn
Jun 30, 2024 -3.75 Bn
Mar 31, 2024 1.31 Bn
Mar 31, 2024 1.31 Bn
Dec 31, 2023 234.60 Mn
Dec 31, 2023 234.60 Mn