Vertex Pharmaceuticals (VRTX) Cash from Operations (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Cash from Operations of 1428100000.0 in Q1 2026, up 186.77% quarter-over-quarter from 498000000.0 in Q4 2025, and up 74.39% on a YoY basis from 818900000.0 in Q1 2025.

Vertex Pharmaceuticals (VRTX) Cash from Operations (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Cash from Operations history runs 18 years deep, the most recent figure standing at 1428100000.0 for Q1 2026.

  • In Q1 2026, Cash from Operations rose 74.39% year-over-year to 1428100000.0; the TTM figure through Mar 2026 stood at 4240600000.0 (up 532.58% YoY), while the FY2025 annual figure was 3631400000.0, up 837.19% from the prior year.
  • Cash from Operations was 1428100000.0 for Q1 2026 at Vertex Pharmaceuticals, up from 498000000.0 in the prior quarter.
  • In the past five years, Cash from Operations ranged from a high of 1428100000.0 in Q1 2026 to a low of 3753600000.0 in Q2 2024.
  • Historically, Cash from Operations has averaged 719652941.18 across 5 years, with a median of 1073100000.0 in 2025.
  • The sharpest annual moves came in 2022 and 2024: Cash from Operations soared 670.76% in 2022, then sank 430.89% in 2024.
  • A 5-year view of Cash from Operations shows it stood at 1078400000.0 in 2022, then slumped by 78.25% to 234600000.0 in 2023, then jumped by 149.19% to 584600000.0 in 2024, then decreased by 14.81% to 498000000.0 in 2025, then soared by 186.77% to 1428100000.0 in 2026.
  • The last three Cash from Operations figures came in at 1428100000.0 (Q1 2026), 498000000.0 (Q4 2025), and 1241400000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Ops. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -1.67 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -12.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.49 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.43 Bn
9 Abivax 91.96 Bn 91.96 Bn - -
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 1.08 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 1.43 Bn
Mar 31, 2026 1.43 Bn
Dec 31, 2025 498.00 Mn
Dec 31, 2025 498.00 Mn
Sep 30, 2025 1.24 Bn
Sep 30, 2025 1.24 Bn
Jun 30, 2025 1.07 Bn
Jun 30, 2025 1.07 Bn
Mar 31, 2025 818.90 Mn
Mar 31, 2025 818.90 Mn
Dec 31, 2024 584.60 Mn
Dec 31, 2024 584.60 Mn
Sep 30, 2024 1.37 Bn
Sep 30, 2024 1.37 Bn
Jun 30, 2024 -3.75 Bn
Jun 30, 2024 -3.75 Bn
Mar 31, 2024 1.31 Bn
Mar 31, 2024 1.31 Bn
Dec 31, 2023 234.60 Mn
Dec 31, 2023 234.60 Mn