Vertex Pharmaceuticals (VRTX) Cash from Investing Activities (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Cash from Investing Activities came in at -$431.9 million in Q1 2026, down 674.01% year-on-year from $75.2 million in Q1 2025, and down 49.91% quarter-over-quarter from -$288.1 million in Q4 2025.

Vertex Pharmaceuticals (VRTX) Cash from Investing Activities (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Cash from Investing Activities history runs 18 years deep, the most recent figure standing at -$431.9 million for Q1 2026.

  • On a quarterly basis, Cash from Investing Activities fell 674.01% year-over-year to -$431.9 million in Q1 2026; TTM through Mar 2026 was -$1.3 billion, a 21.78% increase from a year earlier, with the FY2025 full-year figure at -$945.4 million, up 74.92% from the prior year.
  • Cash from Investing Activities declined to -$431.9 million in Q1 2026 per VRTX's latest filing, from -$288.1 million in the prior quarter.
  • Across five years, Cash from Investing Activities topped out at $175.6 million in Q4 2022 and bottomed at -$2.1 billion in Q1 2024.
  • The 5-year median for Cash from Investing Activities is -$348.0 million (2024), against an average of -$506.5 million.
  • Across the five-year window, Cash from Investing Activities soared 231.04% in 2022 and plunged 3495.29% in 2023, its largest moves.
  • Year by year, Cash from Investing Activities stood at $175.6 million in 2022, then slumped by 604.84% to -$886.5 million in 2023, then climbed by 7.29% to -$821.9 million in 2024, then jumped by 64.95% to -$288.1 million in 2025, then tumbled by 49.91% to -$431.9 million in 2026.
  • Per Business Quant, the three latest VRTX Cash from Investing Activities figures stand at -$431.9 million (Q1 2026), -$288.1 million (Q4 2025), and -$117.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -45.51 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -431.90 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -428.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 172.62 Mn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn -25.54 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -431.90 Mn
Mar 31, 2026 -431.90 Mn
Dec 31, 2025 -288.10 Mn
Dec 31, 2025 -288.10 Mn
Sep 30, 2025 -117.00 Mn
Sep 30, 2025 -117.00 Mn
Jun 30, 2025 -484.50 Mn
Jun 30, 2025 -484.50 Mn
Mar 31, 2025 -55.80 Mn
Mar 31, 2025 -55.80 Mn
Dec 31, 2024 -821.90 Mn
Dec 31, 2024 -821.90 Mn
Sep 30, 2024 -348.00 Mn
Sep 30, 2024 -348.00 Mn
Jun 30, 2024 -463.70 Mn
Jun 30, 2024 -463.70 Mn
Mar 31, 2024 -2.14 Bn
Mar 31, 2024 -2.14 Bn
Dec 31, 2023 -886.50 Mn
Dec 31, 2023 -886.50 Mn