Lexicon Pharmaceuticals (LXRX) Gross Margin (2016 - 2026)
Lexicon Pharmaceuticals (LXRX) posted Gross Margin of 94.36% for Q2 2026, down 5.52 percentage points from 99.89% a year earlier and down 5.12 percentage points from the prior quarter.
Lexicon Pharmaceuticals (LXRX) Gross Margin (2016 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Gross Margin at Lexicon Pharmaceuticals was 99.14%, down 0.04 percentage points year-over-year; for FY2025, it came in at 99.45%, up 1.43 percentage points from FY2024.
- Annual Gross Margin shows a five-year change of +7.49 percentage points (FY2020 to FY2025).
- In prior years, Lexicon Pharmaceuticals' Gross Margin was 98.02% in FY2024 (+5.08 pp), 92.94% in FY2023 (-7.06 pp), 100.00% in FY2022 (unchanged) and 100.00% in FY2021 (+8.04 pp).
- The Q2 2026 figure stands as the lowest quarterly Gross Margin since Q2 2024.
- On a year-over-year basis, Gross Margin increased in six of the last eight quarters, with an average year-over-year change of +2.15 percentage points.
- The strongest year-over-year quarter for Gross Margin in the past five years was Q2 2025, with a gain of 9.96 percentage points; the weakest was Q4 2023, with a drop of 9.97 percentage points.
- According to Business Quant data, Gross Margin for the three prior quarters was 99.49% (Q1 2026), 96.34% (Q4 2025) and 99.93% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 85.33% |
| 10 | Lexicon Pharmaceuticals | 849.05 Mn | 275.61 Mn | 653,000.00 | 94.36% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 94.36% |
| Mar 31, 2026 | 99.49% |
| Dec 31, 2025 | 96.34% |
| Sep 30, 2025 | 99.93% |
| Jun 30, 2025 | 99.89% |
| Mar 31, 2025 | 97.62% |
| Dec 31, 2024 | 98.69% |
| Sep 30, 2024 | 95.94% |
| Jun 30, 2024 | 89.92% |
| Mar 31, 2024 | 97.26% |
| Dec 31, 2023 | 90.03% |
| Sep 30, 2023 | 95.68% |
| Jun 30, 2023 | 97.48% |
| Mar 31, 2023 | 100.00% |
| Dec 31, 2022 | 100.00% |
| Sep 30, 2022 | 100.00% |
| Jun 30, 2022 | 100.00% |
| Dec 31, 2021 | 100.00% |
| Sep 30, 2021 | 100.00% |
| Jun 30, 2021 | 100.00% |
Lexicon Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "LXRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();