Growth Metrics

Pfizer (PFE) Gross Margin (2016 - 2025)

Pfizer (PFE) has disclosed Gross Margin for 17 consecutive years, with 83.48% as the latest value for Q4 2025.

  • On a quarterly basis, Gross Margin fell 3229.0% to 83.48% in Q4 2025 year-over-year; TTM through Dec 2025 was 74.33%, a 11454.0% decrease, with the full-year FY2025 number at 74.33%, up 18714.0% from a year prior.
  • Gross Margin was 83.48% for Q4 2025 at Pfizer, up from 81.51% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 115.77% in Q4 2024 to a low of 1090.72% in Q3 2024.
  • A 5-year average of 29.0% and a median of 62.04% in 2021 define the central range for Gross Margin.
  • Peak YoY movement for Gross Margin: crashed -112202bps in 2024, then skyrocketed 100922bps in 2025.
  • Pfizer's Gross Margin stood at 58.78% in 2021, then increased by 25bps to 73.22% in 2022, then crashed by -264bps to 120.21% in 2023, then soared by 196bps to 115.77% in 2024, then decreased by -28bps to 83.48% in 2025.
  • Per Business Quant, the three most recent readings for PFE's Gross Margin are 83.48% (Q4 2025), 81.51% (Q3 2025), and 74.21% (Q2 2025).