Lakefront Biotherapeutics (LKFT) Operating Margin (2014 - 2026)
Lakefront Biotherapeutics' Operating Margin came in at -358.92% for the quarter ended Jun 30, 2026, down 271.67 percentage points from -87.25% a year earlier but up 624.00 percentage points from the prior quarter.
Lakefront Biotherapeutics (LKFT) Operating Margin (2014 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Lakefront Biotherapeutics reported Operating Margin of 40.59%, up 139.65 percentage points year-over-year; for the year ended Dec 31, 2025, it was 26.53%, up 94.85 percentage points from the prior year.
- Operating Margin carries a five-year change of +63.89 percentage points (years ended Dec 2020 to Dec 2025).
- Going back by year, Operating Margin was -68.33% in the year ended Dec 31, 2024 (-31.51 pp), -36.82% in the year ended Dec 31, 2023 (+17.51 pp), -54.32% in the year ended Dec 31, 2022 (+18.88 pp) and -73.20% in the year ended Dec 31, 2021 (-35.83 pp).
- The five-year range for quarterly Operating Margin is -982.92% (the quarter ended Mar 31, 2026) to 190.13% (the quarter ended Dec 31, 2024).
- Year-over-year, Operating Margin has declined for four consecutive quarters, with an average year-over-year change of -211.53 percentage points over the last seven quarters.
- The fastest year-over-year change in Operating Margin over five years came in the quarter ended Dec 31, 2024 (a gain of 150.17 percentage points), and the weakest in the quarter ended Mar 31, 2026 (a drop of 771.24 percentage points).
- Business Quant data shows LKFT's Operating Margin at -982.92% (quarter ended Mar 31, 2026), 84.06% (quarter ended Dec 31, 2025) and -346.51% (quarter ended Sep 30, 2025) in the three quarters before the quarter ended Jun 30, 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Lakefront Biotherapeutics | 1.97 Bn | 1.97 Bn | 3.51 Mn | -358.92% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -358.92% |
| Mar 31, 2026 | -982.92% |
| Dec 31, 2025 | 84.06% |
| Sep 30, 2025 | -346.51% |
| Jun 30, 2025 | -87.25% |
| Mar 31, 2025 | -211.68% |
| Dec 31, 2024 | 190.13% |
| Sep 30, 2024 | -119.07% |
| Mar 31, 2024 | -53.07% |
| Dec 31, 2023 | 39.96% |
| Sep 30, 2023 | -23.23% |
| Jun 30, 2023 | -22.49% |
| Mar 31, 2023 | -24.24% |
| Sep 30, 2022 | -27.58% |
| Jun 30, 2022 | -55.47% |
| Mar 31, 2022 | -15.51% |
| Sep 30, 2021 | -55.27% |
| Jun 30, 2021 | -33.45% |
| Mar 31, 2021 | -44.60% |
| Dec 31, 2020 | -33.68% |
Lakefront Biotherapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=LKFT&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "LKFT", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=LKFT&period=max&api_key=YOUR_API_KEY");
const data = await res.json();