LENZ Therapeutics (LENZ) Operating Margin (2025 - 2026)
LENZ Therapeutics (LENZ) reported Operating Margin of -622.89% for Q2 2026, down 285.75 percentage points from -337.14% a year earlier but up 1698.78 percentage points from the prior quarter.
Powered by 
Analysis
LENZ Therapeutics (LENZ) Operating Margin (2025 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, LENZ Therapeutics' Operating Margin came in at -631.70%, up 607.46 percentage points year-over-year; for FY2025, it was -477.46%.
- Operating Margin has a three-year change of +226.80 percentage points (FY2022 to FY2025).
- By year, Operating Margin came in at -704.26% in FY2022.
- Five-year quarterly Operating Margin spans a low of -2422.10% in Q4 2025 and a high of -151.10% in Q3 2025.
- Per Business Quant data, the three quarters before Q2 2026 came in at -2321.67% (Q1 2026), -2422.10% (Q4 2025) and -151.10% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 28.37% |
| 10 | LENZ Therapeutics | 101.65 Mn | -871.25 Mn | 5.21 Mn | -622.89% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -622.89% |
| Mar 31, 2026 | -2,321.67% |
| Dec 31, 2025 | -2,422.10% |
| Sep 30, 2025 | -151.10% |
| Jun 30, 2025 | -337.14% |
API Access
LENZ Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=LENZ&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "LENZ", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=LENZ&period=max&api_key=YOUR_API_KEY");
const data = await res.json();